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Acute and subchronic oral toxicity assessment of extract from Etlingera pavieana rhizomes.
Chiranthanut N, Lertprasertsuke N, Srisook E, Srisook K. Chiranthanut N, et al. Toxicol Rep. 2022 Aug 8;9:1472-1483. doi: 10.1016/j.toxrep.2022.07.005. eCollection 2022. Toxicol Rep. 2022. PMID: 36518420 Free PMC article.
However, its potential toxicity has not been described. This study aimed to evaluate in vivo toxicity of E. pavieana rhizome extract (EPE) in Sprague Dawley rats. Acute toxicity testing of EPE at a single dose of 2,000 mg/kg produced no toxic effects in female rats after 1 …
However, its potential toxicity has not been described. This study aimed to evaluate in vivo toxicity of E. pavieana rhizome extract …
Anti-inflammatory effect of trans-4-methoxycinnamaldehyde from Etlingera pavieana in LPS-stimulated macrophages mediated through inactivation of NF-κB and JNK/c-Jun signaling pathways and in rat models of acute inflammation.
Srisook K, Mankhong S, Chiranthanut N, Kongsamak K, Kitwiwat NT, Tongjurai P, Aramsangtienchai P. Srisook K, et al. Toxicol Appl Pharmacol. 2019 May 15;371:3-11. doi: 10.1016/j.taap.2019.03.026. Epub 2019 Mar 31. Toxicol Appl Pharmacol. 2019. PMID: 30943385
In this study, we investigated this mechanism in lipopolysaccharide (LPS)-induced RAW 264.7 macrophages and found MCD significantly inhibited nitric oxide (NO) and prostaglandin E(2) (PGE(2)) production in a concentration-dependent manner. MCD could decrease LPS- and Pam3C …
In this study, we investigated this mechanism in lipopolysaccharide (LPS)-induced RAW 264.7 macrophages and found MCD significantly inhibite …
Antimicrobial resistance, virulence profile, and genetic analysis of ESBL-producing Escherichia coli isolated from Nile tilapia in fresh markets and supermarkets in Thailand.
Hinthong W, Thaotumpitak V, Sripradite J, Indrawattana N, Srisook T, Kongngoen T, R Atwill E, Jeamsripong S. Hinthong W, et al. PLoS One. 2024 Jan 12;19(1):e0296857. doi: 10.1371/journal.pone.0296857. eCollection 2024. PLoS One. 2024. PMID: 38215169 Free PMC article.
This study investigated the prevalence and antimicrobial resistance (AMR) of Escherichia coli (E. coli) in Nile tilapia from fresh markets and supermarkets. A total of samples (n = 828) were collected from Nile tilapia including fish flesh (n = 276), liver and kidney (n = …
This study investigated the prevalence and antimicrobial resistance (AMR) of Escherichia coli (E. coli) in Nile tilapia from fresh ma …
Etlingera pavieana extract attenuates TNF-α induced vascular adhesion molecule expression in human endothelial cells through NF-κB and Akt/JNK pathways.
Srisook K, Potiprasart K, Sarapusit S, Park CS, Srisook E. Srisook K, et al. Inflammopharmacology. 2020 Dec;28(6):1649-1662. doi: 10.1007/s10787-019-00676-4. Epub 2019 Dec 12. Inflammopharmacology. 2020. PMID: 31832850
Taken together, our data indicate that EPE protects against vascular inflammation in endothelial cells, in part via NF-kappaB and Akt/JNK signalings. In future studies, E. pavieana may be developed as a therapeutic agent or dietary supplement for treating and preventing in …
Taken together, our data indicate that EPE protects against vascular inflammation in endothelial cells, in part via NF-kappaB and Akt/JNK si …
Green synthesis and anti-inflammatory studies of a series of 1,1-bis(heteroaryl)alkane derivatives.
Jaratjaroonphong J, Tuengpanya S, Saeeng R, Udompong S, Srisook K. Jaratjaroonphong J, et al. Eur J Med Chem. 2014 Aug 18;83:561-8. doi: 10.1016/j.ejmech.2014.06.045. Epub 2014 Jun 23. Eur J Med Chem. 2014. PMID: 24996142
Molecular iodine has been used as an efficient catalyst for a double Friedel-Crafts reaction of various heteroarenes, i.e. 2-methylfuran, 2-ethylfuran, 2-methylthiophene, pyrrole, N-methylpyrrole and indole, using aldehydes as alkylating agents under "open-flask" condition …
Molecular iodine has been used as an efficient catalyst for a double Friedel-Crafts reaction of various heteroarenes, i.e. 2-methylfu …
Electrophilic aromatic addition reaction: electrophilic attack at an aromatic H substituent position.
Choi HY, Srisook E, Jang KS, Chi DY. Choi HY, et al. J Org Chem. 2005 Feb 18;70(4):1222-6. doi: 10.1021/jo048297x. J Org Chem. 2005. PMID: 15704954
[reaction: see text] We report and propose a mechanism for an unusual electrophilic aromatic addition reaction (Ad(E)()Ar). During our preparation of 5,7-dibromo-8-methoxyquinaldine as a key intermediate in the synthesis of 7-bromoquinaldine-5,8-dione, direct bromination i …
[reaction: see text] We report and propose a mechanism for an unusual electrophilic aromatic addition reaction (Ad(E)()Ar). During ou …
Involvement of p38 MAPK and ATF-2 signaling pathway in anti-inflammatory effect of a novel compound bis[(5-methyl)2-furyl](4-nitrophenyl)methane on lipopolysaccharide-stimulated macrophages.
Udompong S, Mankhong S, Jaratjaroonphong J, Srisook K. Udompong S, et al. Int Immunopharmacol. 2017 Sep;50:6-13. doi: 10.1016/j.intimp.2017.05.015. Epub 2017 Jun 12. Int Immunopharmacol. 2017. PMID: 28618389
Activated macrophages produce various pro-inflammatory mediators such as inducible nitric oxide synthase (iNOS)-derived nitric oxide (NO) and cyclooxygenase (COX)-2-derived prostaglandin E(2) (PGE(2)) during inflammatory response. However, overproduction of NO and PGE(2) a …
Activated macrophages produce various pro-inflammatory mediators such as inducible nitric oxide synthase (iNOS)-derived nitric oxide (NO) an …
Anti-inflammatory Effect of Etlingera pavieana (Pierre ex Gagnep.) R.M.Sm. Rhizomal Extract and Its Phenolic Compounds in Lipopolysaccharide-Stimulated Macrophages.
Srisook E, Palachot M, Mankhong S, Srisook K. Srisook E, et al. Pharmacogn Mag. 2017 Jul;13(Suppl 2):S230-S235. doi: 10.4103/pm.pm_558_16. Epub 2017 Jul 11. Pharmacogn Mag. 2017. PMID: 28808385 Free PMC article.
OBJECTIVE: In the present study, anti-inflammatory effect of hexane, ethyl acetate, and water fractions of rhizomal ethanol extracts of E. pavieana was evaluated for their inhibition on NO production and mechanism in LPS-stimulated macrophages. ...Anti-inflammatory compoun …
OBJECTIVE: In the present study, anti-inflammatory effect of hexane, ethyl acetate, and water fractions of rhizomal ethanol extracts of E …
11 results