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Year Number of Results
1967 1
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1980 1
1981 1
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1985 1
1986 3
1987 3
1988 3
1989 2
1990 8
1991 5
1992 3
1993 5
1994 9
1995 3
1996 6
1997 4
1998 3
1999 3
2000 3
2001 2
2002 1
2003 2
2005 3
2006 1
2007 1
2008 2
2009 2
2010 2
2011 1
2012 3
2013 2
2015 2
2017 1
2021 6
2022 3
2024 0

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99 results

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Page 1
Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma.
Vos JL, Elbers JBW, Krijgsman O, Traets JJH, Qiao X, van der Leun AM, Lubeck Y, Seignette IM, Smit LA, Willems SM, van den Brekel MWM, Dirven R, Baris Karakullukcu M, Karssemakers L, Klop WMC, Lohuis PJFM, Schreuder WH, Smeele LE, van der Velden LA, Bing Tan I, Onderwater S, Jasperse B, Vogel WV, Al-Mamgani A, Keijser A, van der Noort V, Broeks A, Hooijberg E, Peeper DS, Schumacher TN, Blank CU, de Boer JP, Haanen JBAG, Zuur CL. Vos JL, et al. Nat Commun. 2021 Dec 22;12(1):7348. doi: 10.1038/s41467-021-26472-9. Nat Commun. 2021. PMID: 34937871 Free PMC article. Clinical Trial.
We observe a major pathological response (MPR, 90-100% response) in 35% of patients after COMBO ICB, both in phase IIa (6/17) and in the whole trial (8/23), meeting the phase IIa primary endpoint threshold of 10%. NIVO MONO's MPR rate is 17% (1/6). None of the MPR p …
We observe a major pathological response (MPR, 90-100% response) in 35% of patients after COMBO ICB, both in phase IIa (6/17) and in the who …
Heritability of venous biomechanics.
Molnár AÀ, Tárnoki AD, Tárnoki DL, Kulcsár Z, Littvay L, Garami Z, Préda I, Kiss RG, Bérczi V, Lannert A, Monos E, Nádasy GL. Molnár AÀ, et al. Arterioscler Thromb Vasc Biol. 2013 Jan;33(1):152-7. doi: 10.1161/ATVBAHA.112.300062. Epub 2012 Nov 1. Arterioscler Thromb Vasc Biol. 2013. PMID: 23117659
High correlation of diameter, capacity, and distensibility values was found between twin pairs. The univariate heritability (A), shared (C), and unshared (E) environmental effects model has shown 39.3% genetic component of the variance of low pressure, 37.9% of high-pressu …
High correlation of diameter, capacity, and distensibility values was found between twin pairs. The univariate heritability (A), shared (C), …
Chemical profiles and metabolite study of raw and processed Cistanche deserticola in rats by UPLC-Q-TOF-MS(E).
Li Z, Ryenchindorj L, Liu B, Shi J, Zhang C, Hua Y, Liu P, Shan G, Jia T. Li Z, et al. Chin Med. 2021 Sep 28;16(1):95. doi: 10.1186/s13020-021-00508-0. Chin Med. 2021. PMID: 34583715 Free PMC article.
METHODS: A comparison analysis was carried out using the UPLC-Q-TOF-MS(E) with the UNIFI informatics platform to determine the influence of processing. ...
METHODS: A comparison analysis was carried out using the UPLC-Q-TOF-MS(E) with the UNIFI informatics platform to determine the influe …
Purification of staphylococcal enterotoxin E.
Brehm RD, Tranter HS. Brehm RD, et al. Nat Toxins. 1993;1(4):250-4. doi: 10.1002/nt.2620010409. Nat Toxins. 1993. PMID: 8167943
Staphylococcal enterotoxin E has been purified by a combination of Red-A ligand chromatography and Mono-S (cation-exchange) chromatography. ...
Staphylococcal enterotoxin E has been purified by a combination of Red-A ligand chromatography and Mono-S (cation-excha …
Genetic, maternal, and environmental influences on sociality in a pedigreed primate population.
Godoy I, Korsten P, Perry SE. Godoy I, et al. Heredity (Edinb). 2022 Oct;129(4):203-214. doi: 10.1038/s41437-022-00558-6. Epub 2022 Sep 2. Heredity (Edinb). 2022. PMID: 36056208 Free PMC article.
Various aspects of sociality in mammals (e.g., dyadic connectedness) are linked with measures of biological fitness (e.g., longevity). ...
Various aspects of sociality in mammals (e.g., dyadic connectedness) are linked with measures of biological fitness (e.g., lon …
Superexpression and fast purification of E coli initiation factor IF2.
Mortensen KK, Nyengaard NR, Hershey JW, Laalami S, Sperling-Petersen HU. Mortensen KK, et al. Biochimie. 1991 Jul-Aug;73(7-8):983-9. doi: 10.1016/0300-9084(91)90139-r. Biochimie. 1991. PMID: 1742367
For the production of large quantities of E coli initiation factor IF2 we have constructed an improved overexpression system. ...From these cells pure and active IF2 was obtained using a novel 3-step FPLC-procedure consisting of ion-exchange liquid chromatography on Q-seph …
For the production of large quantities of E coli initiation factor IF2 we have constructed an improved overexpression system. ...From …
Complexity of malaria transmission dynamics in the Brazilian Atlantic Forest.
Ribeiro de Castro Duarte AM, Fernandes LN, Silva FS, Sicchi IL, Mucci LF, Curado I, Fernandes A, Medeiros-Sousa AR, Ceretti-Junior W, Marrelli MT, Evangelista E, Teixeira R, Summa JL, Nardi MS, Garnica MR, Loss AC, Buery JC, Cerutti C Jr, Pacheco MA, Escalante AA, Mureb Sallum MA, Laporta GZ. Ribeiro de Castro Duarte AM, et al. Curr Res Parasitol Vector Borne Dis. 2021 May 31;1:100032. doi: 10.1016/j.crpvbd.2021.100032. eCollection 2021. Curr Res Parasitol Vector Borne Dis. 2021. PMID: 35284897 Free PMC article.
They are genetically indistinguishable from, respectively, Plasmodium brasilianum and Plasmodium simium, i.e. parasites infecting New World non-human primates in South America. ...The findings of this study indicate complex malaria transmission dynamics composed by paralle …
They are genetically indistinguishable from, respectively, Plasmodium brasilianum and Plasmodium simium, i.e. parasites infecting New …
Purification and characterization of phospholipase C-beta 1 mutants expressed in E. coli.
Meij JT, Ross EM. Meij JT, et al. Biochem Biophys Res Commun. 1996 Aug 23;225(3):705-11. doi: 10.1006/bbrc.1996.1239. Biochem Biophys Res Commun. 1996. PMID: 8780678
To rapidly evaluate in vitro PLC-beta 1 mutants constructed by oligonucleotide-directed mutagenesis, we established a quick expression and purification procedure. A pQE60/His6PLC-beta 1 construct was expressed in E. coli SG13009[pREP4]. Purification (approximately 160-fold …
To rapidly evaluate in vitro PLC-beta 1 mutants constructed by oligonucleotide-directed mutagenesis, we established a quick expression and p …
Purification of recombinant HIV-1 protease.
Margolin N, Dee A, Lai M, Vlahos CJ. Margolin N, et al. Prep Biochem. 1991;21(2-3):163-73. doi: 10.1080/10826069108018011. Prep Biochem. 1991. PMID: 1798693
The isolation involves QAE-Sepharose anion exchange chromatography, hexyl agarose hydrophobic interaction chromatography, MonoS cation exchange chromatography, and Superose 6 size exclusion chromatography. Approximately 100 micrograms of protease was obtained from 18 g …
The isolation involves QAE-Sepharose anion exchange chromatography, hexyl agarose hydrophobic interaction chromatography, MonoS catio …
Tandem translation of E. coli initiation factor IF2 beta: purification and characterization in vitro of two active forms.
Nyengaard NR, Mortensen KK, Lassen SF, Hershey JW, Sperling-Petersen HU. Nyengaard NR, et al. Biochem Biophys Res Commun. 1991 Dec 31;181(3):1572-9. doi: 10.1016/0006-291x(91)92118-4. Biochem Biophys Res Commun. 1991. PMID: 1764105
We have recently described a fast purification method for IF2 alpha, using an FPLC procedure consisting of ion-exchange liquid chromatography on Q Sepharose HP, Mono Q and Mono S. After the Mono Q step, an apparently homogeneous IF2 beta was observed when analyzed b …
We have recently described a fast purification method for IF2 alpha, using an FPLC procedure consisting of ion-exchange liquid chromatograph …
99 results