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Pharmacological blockade of neurokinin1 receptor restricts morphine-induced tolerance and hyperalgesia in the rat.
Rahban M, Danyali S, Zaringhalam J, Manaheji H. Rahban M, et al. Scand J Pain. 2021 Sep 16;22(1):193-203. doi: 10.1515/sjpain-2021-0052. Print 2022 Jan 27. Scand J Pain. 2021. PMID: 34525274 Free article.
Behavioral tests were performed on days 1 and 8 before and after the first injections and then 48 h after the last injection (day 10). In the treatment groups, rats received NK1R antagonist (L-732,138, 25 g) daily, either alone or 10 min before a morphine injection, Sham g …
Behavioral tests were performed on days 1 and 8 before and after the first injections and then 48 h after the last injection (day 10) …
The Potential Role of Glycogen Synthase Kinase-3β in Neuropathy-Induced Apoptosis in Spinal Cord.
Rashvand M, Danyali S, Manaheji H. Rashvand M, et al. Basic Clin Neurosci. 2020 Jan-Feb;11(1):15-30. doi: 10.32598/bcn.11.1.1. Epub 2020 Jan 1. Basic Clin Neurosci. 2020. PMID: 32483472 Free PMC article.
GSK-3beta selective inhibitor, AR-014418 [0.3 mg/kg, Intraperitoneal (IP)] was administrated 1 h prior to SNL on day 0, then daily up to the day 8. The GSK-3beta activity and apoptosis in the lumbar section (L4, L5, or L6) of the study rat's spinal cord were assessed by im …
GSK-3beta selective inhibitor, AR-014418 [0.3 mg/kg, Intraperitoneal (IP)] was administrated 1 h prior to SNL on day 0, then daily up …
Role of spinal glial cells in excitability of wide dynamic range neurons and the development of neuropathic pain with the L5 spinal nerve transection in the rats: Behavioral and electrophysiological study.
Rezaee L, Manaheji H, Haghparast A. Rezaee L, et al. Physiol Behav. 2019 Oct 1;209:112597. doi: 10.1016/j.physbeh.2019.112597. Epub 2019 Jul 2. Physiol Behav. 2019. PMID: 31271834
In these experiments, spinal nerve ligation (SNL) and a daily injection of propentofylline (1 mg/kg, ip) as a glial cell inhibitor agent, 1 h following nerve ligation during 7-day post-SNL period, were performed. ...
In these experiments, spinal nerve ligation (SNL) and a daily injection of propentofylline (1 mg/kg, ip) as a glial cell inhibitor agent, 1 …
Suppression of interleukin-6 by minocycline in a rat model of neuropathic pain.
Zanjani TM, Sabetkasaei M, Mosaffa N, Manaheji H, Labibi F, Farokhi B. Zanjani TM, et al. Eur J Pharmacol. 2006 May 24;538(1-3):66-72. doi: 10.1016/j.ejphar.2006.03.063. Epub 2006 Apr 5. Eur J Pharmacol. 2006. PMID: 16687137
The present study, evaluated the effect of pretreatment with minocycline, on pain behavior (hyperalgesia and allodynia) and serum level of interleukin-6 in chronic constriction injury (CCI) model of neuropathic pain in rat. Minocycline (5, 10, 20 and 40 mg/kg, i.p.) was injected …
The present study, evaluated the effect of pretreatment with minocycline, on pain behavior (hyperalgesia and allodynia) and serum level of i …
Recovery of inferior alveolar nerve by photobiomodulation therapy using two laser wavelengths: A behavioral and immunological study in rat.
Hakimiha N, Dehghan MM, Manaheji H, Zaringhalam J, Farzad-Mohajeri S, Fekrazad R, Moslemi N. Hakimiha N, et al. J Photochem Photobiol B. 2020 Mar;204:111785. doi: 10.1016/j.jphotobiol.2020.111785. Epub 2020 Jan 10. J Photochem Photobiol B. 2020. PMID: 31954267
Seventy-two rats were randomly assigned to the four groups of 810 nm laser (crush injury+810 nm laser; 6 J/cm(2), 15 sessions, every 48 h), 980 nm laser (crush injury+980 nm laser; same protocol), control (crush injury without irradiation), and sham surgery (no crush injur …
Seventy-two rats were randomly assigned to the four groups of 810 nm laser (crush injury+810 nm laser; 6 J/cm(2), 15 sessions, every 48 h …
Co-administration of MK-801 and morphine attenuates neuropathic pain in rat.
Hamidi GA, Manaheji H, Janahmadi M, Noorbakhsh SM, Salami M. Hamidi GA, et al. Physiol Behav. 2006 Jul 30;88(4-5):628-35. doi: 10.1016/j.physbeh.2006.05.017. Epub 2006 Jul 3. Physiol Behav. 2006. PMID: 16815501
The animals were injected a combination of MK-801 (0.3 mg/kg, 20 min before, and 6 h after the operation) and morphine (8 mg/kg, 30 min prior to the operation) and were tested for allodynia and hyperalgesia reactions at 0, 3, 7, 14, 21 and 28 days after CCI. ...
The animals were injected a combination of MK-801 (0.3 mg/kg, 20 min before, and 6 h after the operation) and morphine (8 mg/kg, 30 m …