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Showing results for h pourgholami
Your search for H Pourgholam retrieved no results
Effect of minocycline on pentylenetetrazol-induced chemical kindled seizures in mice.
Ahmadirad N, Shojaei A, Javan M, Pourgholami MH, Mirnajafi-Zadeh J. Ahmadirad N, et al. Neurol Sci. 2014 Apr;35(4):571-6. doi: 10.1007/s10072-013-1552-0. Epub 2013 Oct 15. Neurol Sci. 2014. PMID: 24122023
Chemical kindling was induced by injection of a subthreshold dose of pentylenetetrazol (PTZ; 37.5 mg/kg) in mice on every other day. Two groups of animals received minocycline (25 mg/kg) at 1 h before or 1 h after PTZ injection. Following the last PTZ injection, the …
Chemical kindling was induced by injection of a subthreshold dose of pentylenetetrazol (PTZ; 37.5 mg/kg) in mice on every other day. Two gro …
Solubilisation and cytotoxicity of albendazole encapsulated in cucurbit[n]uril.
Zhao Y, Buck DP, Morris DL, Pourgholami MH, Day AI, Collins JG. Zhao Y, et al. Org Biomol Chem. 2008 Dec 21;6(24):4509-15. doi: 10.1039/b813759e. Epub 2008 Nov 6. Org Biomol Chem. 2008. PMID: 19039358
The aqueous solubilities of albendazole encapsulated in cucurbit[6, 7 and 8]urils (Q[6], Q[7] and Q[8]) have been determined by (1)H NMR spectroscopy, and the effect of encapsulation on their cytotoxicities evaluated. ...
The aqueous solubilities of albendazole encapsulated in cucurbit[6, 7 and 8]urils (Q[6], Q[7] and Q[8]) have been determined by (1)H …
Effects of chronic estradiol benzoate treatment on amygdala kindled seizures in male rats.
Saberi M, Jorjani M, Pourgholami MH. Saberi M, et al. Epilepsy Res. 2001 Jul;46(1):45-51. doi: 10.1016/s0920-1211(01)00257-1. Epilepsy Res. 2001. PMID: 11395288
In the present study, fully kindled male rats were treated with various doses (10, 30 and 50 microg/kg, i.p.) of estradiol benzoate (EB) daily, and kindled seizure parameters such as seizure stage (SS), after discharge duration (ADD) and stage 5 duration (S(5)D) were recorded at …
In the present study, fully kindled male rats were treated with various doses (10, 30 and 50 microg/kg, i.p.) of estradiol benzoate (EB) dai …
The acute effects of estradiol benzoate on amygdala-kindled seizures in male rats.
Saberi M, Pourgholami MH, Jorjani M. Saberi M, et al. Brain Res. 2001 Feb 9;891(1-2):1-6. doi: 10.1016/s0006-8993(00)02788-8. Brain Res. 2001. PMID: 11164804
Fully kindled male rats were treated with various doses of estradiol benzoate (EB, 10, 30 and 50 microg/kg, i.p.) and kindling parameters such as seizure stage (SS), afterdischarge duration (ADD) and stage 5 duration (S5D) were elicited at various times (0.25, 1.5, 3 h and …
Fully kindled male rats were treated with various doses of estradiol benzoate (EB, 10, 30 and 50 microg/kg, i.p.) and kindling parameters su …
Effect of shell-crosslinking of micelles on endocytosis and exocytosis: acceleration of exocytosis by crosslinking.
Kim Y , Pourgholami MH , Morris DL , Lu H , Stenzel MH . Kim Y , et al. Biomater Sci. 2013 Mar 4;1(3):265-275. doi: 10.1039/c2bm00096b. Epub 2012 Dec 21. Biomater Sci. 2013. PMID: 32481852
For comparison, a small molecule (Lucifer yellow) was found to be only marginally faster than the crosslinked micelles (40% in 2 h). These results could have implications on the use polymer-drug conjugates or drug carriers where the drug needs to be released before the pol …
For comparison, a small molecule (Lucifer yellow) was found to be only marginally faster than the crosslinked micelles (40% in 2 h). …
Anticonvulsant action of 2-chloroadenosine injected focally into the perirhinal cortex in amygdaloid kindled rats.
Mirnajafi-Zadeh J, Pourgholami MH, Palizvan MR, Rostampour M, Fallahi M. Mirnajafi-Zadeh J, et al. Epilepsy Res. 1999 Oct;37(1):37-43. doi: 10.1016/s0920-1211(99)00025-x. Epilepsy Res. 1999. PMID: 10515173
Possible anticonvulsant effects of 2-chloroadenosine injected focally into the perirhinal cortex of amygdala kindled rats were investigated over a 2 h period. Animals were microinfused (1 microl) with 2-chloroadenosine (2-CLA; 5, 10, 15, 25 and 100 nM) or artificial cerebr …
Possible anticonvulsant effects of 2-chloroadenosine injected focally into the perirhinal cortex of amygdala kindled rats were investigated …
In vitro and in vivo suppression of growth of hepatocellular carcinoma cells by albendazole.
Pourgholami MH, Woon L, Almajd R, Akhter J, Bowery P, Morris DL. Pourgholami MH, et al. Cancer Lett. 2001 Apr 10;165(1):43-9. doi: 10.1016/s0304-3835(01)00382-2. Cancer Lett. 2001. PMID: 11248417
In this study, albendazole was tested in culture against a range of human, rat and mice hepatocellular carcinoma (HCC) cells and in vivo against human SKHEP-1 tumor growth in nude mice. Albendazole induced a dose-dependent inhibition of [(3)H]thymidine incorporation in all …
In this study, albendazole was tested in culture against a range of human, rat and mice hepatocellular carcinoma (HCC) cells and in vivo aga …
Phase I clinical trial to determine maximum tolerated dose of oral albendazole in patients with advanced cancer.
Pourgholami MH, Szwajcer M, Chin M, Liauw W, Seef J, Galettis P, Morris DL, Links M. Pourgholami MH, et al. Cancer Chemother Pharmacol. 2010 Feb;65(3):597-605. doi: 10.1007/s00280-009-1157-8. Cancer Chemother Pharmacol. 2010. PMID: 19904538 Clinical Trial.
Albendazole was given orally on a day 1-14 of a 3 weekly cycle, starting at 400 mg BD with dose escalation until 1,200 mg BD. Serial blood samples were collected up to 96 h and also on day 8 of cycles 1 and 4. RESULTS: The maximum tolerated dose was 2,400 mg per day (1,200 …
Albendazole was given orally on a day 1-14 of a 3 weekly cycle, starting at 400 mg BD with dose escalation until 1,200 mg BD. Serial blood s …
Pharmacokinetics of albendazole in New Zealand white rabbits: oral versus intraperitoneal administration.
Cai ZY, Galettis P, Lu Y, Morris DL, Pourgholami MH. Cai ZY, et al. Anticancer Res. 2007 Jan-Feb;27(1A):417-22. Anticancer Res. 2007. PMID: 17352262 Free article.
The area under the concentration over time curve of ABZ-SO in the oral group (1010.43 microg/ml/h) was also significantly higher than that of the i.p. group (528.33 microg/ml/h, p < 0.05). ...
The area under the concentration over time curve of ABZ-SO in the oral group (1010.43 microg/ml/h) was also significantly higher than …
18 results