Regenerative engineering of long bones using the small molecule forskolin.
Awale GM, Barajaa MA, Kan HM, Seyedsalehi A, Nam GH, Hosseini FS, Ude CC, Schmidt TA, Lo KW, Laurencin CT.
Awale GM, et al.
Proc Natl Acad Sci U S A. 2023 May 30;120(22):e2219756120. doi: 10.1073/pnas.2219756120. Epub 2023 May 22.
Proc Natl Acad Sci U S A. 2023.
PMID: 37216527
Free PMC article.
Previously, we have demonstrated that a single-dose treatment with the small-molecule forskolin for just 24 h induces osteogenic differentiation of rabbit bone marrow-derived stem cells in vitro, while mitigating adverse side effects attributed with prolonged small-molecul …
Previously, we have demonstrated that a single-dose treatment with the small-molecule forskolin for just 24 h induces osteogenic diff …