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A Tripeptide-Stabilized Nanoemulsion of Oleic Acid.
Dragulska SA, Wlodarczyk MT, Poursharifi M, Martignetti JA, Mieszawska AJ. Dragulska SA, et al. J Vis Exp. 2019 Feb 27;(144). doi: 10.3791/59034. J Vis Exp. 2019. PMID: 30882795
Hepatic glycerol shunt and glycerol-3-phosphate phosphatase control liver metabolism and glucodetoxification under hyperglycemia.
Al-Mass A, Poursharifi P, Peyot ML, Lussier R, Chenier I, Leung YH, Ghosh A, Oppong A, Possik E, Mugabo Y, Ahmad R, Sladek R, Murthy Madiraju SR, Al-Mulla F, Prentki M. Al-Mass A, et al. Mol Metab. 2022 Dec;66:101609. doi: 10.1016/j.molmet.2022.101609. Epub 2022 Oct 2. Mol Metab. 2022. PMID: 36198384 Free PMC article.
Hyperglycemia (16-20 mM) was induced by glucose infusion for 55 h. Hepatocytes were isolated from normoglycemic mice for ex vivo studies and targeted metabolomics were measured in mice liver after glucose infusion. ...
Hyperglycemia (16-20 mM) was induced by glucose infusion for 55 h. Hepatocytes were isolated from normoglycemic mice for ex vivo stud …
Effects of Onosma dichroanthum Boiss. root extract on AGS human gastric cancer cell-line.
Hashemi MM, Marjani M, Poursharifi N, Marjani A. Hashemi MM, et al. J Basic Clin Physiol Pharmacol. 2021 Jun 29;33(4):487-492. doi: 10.1515/jbcpp-2020-0323. J Basic Clin Physiol Pharmacol. 2021. PMID: 34182616
The evaluation of different concentrations of root extract was performed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The 48 h treatment affected cell survival, while the concentration of 64 mug/mL was determined as IC(50) concentrations at …
The evaluation of different concentrations of root extract was performed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MT …
Engineering and Validation of a Peptide-Stabilized Poly(lactic-co-glycolic) Acid Nanoparticle for Targeted Delivery of a Vascular Disruptive Agent in Cancer Therapy.
Dragulska SA, Poursharifi M, Chen Y, Wlodarczyk MT, Acosta Santiago M, Dottino P, Martignetti JA, Mieszawska AJ. Dragulska SA, et al. Bioconjug Chem. 2022 Dec 21;33(12):2348-2360. doi: 10.1021/acs.bioconjchem.2c00418. Epub 2022 Nov 11. Bioconjug Chem. 2022. PMID: 36367382 Free PMC article.
The RGDFFF-CA4 NPs are synthesized using a nanoprecipitation method and are 75 3.7 nm in diameter, where a peptide coating comprises a 2-3 nm outer layer. The NPs are serum stable for 72 h. In vitro studies using human umbilical cord vascular endothelial cells (HUVEC) conf …
The RGDFFF-CA4 NPs are synthesized using a nanoprecipitation method and are 75 3.7 nm in diameter, where a peptide coating comprises a 2-3 n …
Substance P decreases fat storage and increases adipocytokine production in 3T3-L1 adipocytes.
Miegueu P, St-Pierre DH, Lapointe M, Poursharifi P, Lu H, Gupta A, Cianflone K. Miegueu P, et al. Am J Physiol Gastrointest Liver Physiol. 2013 Feb 15;304(4):G420-7. doi: 10.1152/ajpgi.00162.2012. Epub 2012 Dec 20. Am J Physiol Gastrointest Liver Physiol. 2013. PMID: 23257919 Free article.
We examined SP effects on lipid storage and cytokine production in 3T3-L1 adipocytes and adipose tissues. 3T3-L1 adipocytes and preadipocytes express NK1R, and 8 days of SP supplementation during differentiation to 3T3-L1 preadipocytes decreased lipid droplet accumulation. SP (10 …
We examined SP effects on lipid storage and cytokine production in 3T3-L1 adipocytes and adipose tissues. 3T3-L1 adipocytes and preadipocyte …
Identification of a mammalian glycerol-3-phosphate phosphatase: Role in metabolism and signaling in pancreatic β-cells and hepatocytes.
Mugabo Y, Zhao S, Seifried A, Gezzar S, Al-Mass A, Zhang D, Lamontagne J, Attane C, Poursharifi P, Iglesias J, Joly E, Peyot ML, Gohla A, Madiraju SR, Prentki M. Mugabo Y, et al. Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):E430-9. doi: 10.1073/pnas.1514375113. Epub 2016 Jan 11. Proc Natl Acad Sci U S A. 2016. PMID: 26755581 Free PMC article.
Acute effects of protein composition and fibre enrichment of yogurt consumed as snacks on appetite sensations and subsequent ad libitum energy intake in healthy men.
Doyon CY, Tremblay A, Rioux LE, Rhéaume C, Cianflone K, Poursharifi P, Turgeon SL. Doyon CY, et al. Appl Physiol Nutr Metab. 2015 Oct;40(10):980-9. doi: 10.1139/apnm-2014-0403. Epub 2015 Sep 22. Appl Physiol Nutr Metab. 2015. PMID: 26394259 Clinical Trial.
Plasma variables (glucose, insulin, ghrelin) were measured at 30-min intervals post-yogurt consumption for 2 h. Finally, energy intakes during ad libitum lunches offered 2 h after yogurt snacks were recorded. ...
Plasma variables (glucose, insulin, ghrelin) were measured at 30-min intervals post-yogurt consumption for 2 h. Finally, energy intak …