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Page 1
Inhibition of SARS-CoV-2 main protease: a repurposing study that targets the dimer interface of the protein.
J Biomol Struct Dyn. 2022 Sep;40(15):7167-7182. doi: 10.1080/07391102.2021.1910571. Epub 2021 Apr 13.
J Biomol Struct Dyn. 2022.
PMID: 33847241
Free PMC article.
Mechanistic insight into impact of phosphorylation on the enzymatic steps of farnesyltransferase.
Pekel H, Guzel M, Sensoy O.
Pekel H, et al.
Protein Sci. 2022 Oct;31(10):e4414. doi: 10.1002/pro.4414.
Protein Sci. 2022.
PMID: 36173156
Free PMC article.
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Dimethyl sulfoxide reduces the stability but enhances catalytic activity of the main SARS-CoV-2 protease 3CLpro.
Ferreira JC, Fadl S, Ilter M, Pekel H, Rezgui R, Sensoy O, Rabeh WM.
Ferreira JC, et al. Among authors: pekel h.
FASEB J. 2021 Aug;35(8):e21774. doi: 10.1096/fj.202100994.
FASEB J. 2021.
PMID: 34324734
Free PMC article.
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Design and synthesis of novel cylopentapyrazoles bearing 1,2,3-thiadiazole moiety as potent antifungal agents.
Giray B, Karadağ AE, İpek ÖŞ, Pekel H, Güzel M, Küçük HB.
Giray B, et al. Among authors: pekel h.
Bioorg Chem. 2020 Jan;95:103509. doi: 10.1016/j.bioorg.2019.103509. Epub 2019 Dec 24.
Bioorg Chem. 2020.
PMID: 31884141
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Synthesis, Structural Investigations, DNA/BSA Interactions, Molecular Docking Studies, and Anticancer Activity of a New 1,4-Disubstituted 1,2,3-Triazole Derivative.
Göktürk T, Sakallı Çetin E, Hökelek T, Pekel H, Şensoy Ö, Aksu EN, Güp R.
Göktürk T, et al. Among authors: pekel h.
ACS Omega. 2023 Aug 25;8(35):31839-31856. doi: 10.1021/acsomega.3c03355. eCollection 2023 Sep 5.
ACS Omega. 2023.
PMID: 37692230
Free PMC article.
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