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2009 1
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2013 3
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2023 4
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26 results

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Page 1
Stroke genetics informs drug discovery and risk prediction across ancestries.
Mishra A, Malik R, Hachiya T, Jürgenson T, Namba S, Posner DC, Kamanu FK, Koido M, Le Grand Q, Shi M, He Y, Georgakis MK, Caro I, Krebs K, Liaw YC, Vaura FC, Lin K, Winsvold BS, Srinivasasainagendra V, Parodi L, Bae HJ, Chauhan G, Chong MR, Tomppo L, Akinyemi R, Roshchupkin GV, Habib N, Jee YH, Thomassen JQ, Abedi V, Cárcel-Márquez J, Nygaard M, Leonard HL, Yang C, Yonova-Doing E, Knol MJ, Lewis AJ, Judy RL, Ago T, Amouyel P, Armstrong ND, Bakker MK, Bartz TM, Bennett DA, Bis JC, Bordes C, Børte S, Cain A, Ridker PM, Cho K, Chen Z, Cruchaga C, Cole JW, de Jager PL, de Cid R, Endres M, Ferreira LE, Geerlings MI, Gasca NC, Gudnason V, Hata J, He J, Heath AK, Ho YL, Havulinna AS, Hopewell JC, Hyacinth HI, Inouye M, Jacob MA, Jeon CE, Jern C, Kamouchi M, Keene KL, Kitazono T, Kittner SJ, Konuma T, Kumar A, Lacaze P, Launer LJ, Lee KJ, Lepik K, Li J, Li L, Manichaikul A, Markus HS, Marston NA, Meitinger T, Mitchell BD, Montellano FA, Morisaki T, Mosley TH, Nalls MA, Nordestgaard BG, O'Donnell MJ, Okada Y, Onland-Moret NC, Ovbiagele B, Peters A, Psaty BM, Rich SS, Rosand J, Sabatine MS, Sacco RL, Saleheen D, Sandset EC, Salomaa V, Sargurupremraj M, Sasaki M, Satizabal CL, Schmidt CO, Sh… See abstract for full author list ➔ Mishra A, et al. Nature. 2022 Nov;611(7934):115-123. doi: 10.1038/s41586-022-05165-3. Epub 2022 Sep 30. Nature. 2022. PMID: 36180795 Free PMC article.
MicroRNAs as Potential Pharmaco-targets in Ischemia-Reperfusion Injury Compounded by Diabetes.
Dehaini H, Awada H, El-Yazbi A, Zouein FA, Issa K, Eid AA, Ibrahim M, Badran A, Baydoun E, Pintus G, Eid AH. Dehaini H, et al. Cells. 2019 Feb 12;8(2):152. doi: 10.3390/cells8020152. Cells. 2019. PMID: 30759843 Free PMC article. Review.
BACKGROUND: Ischemia-Reperfusion (I/R) injury is the tissue damage that results from re-oxygenation of ischemic tissues. ...METHODS: PubMed was searched for publications containing microRNA and I/R, in the absence or presence of diabetes. All papers th …
BACKGROUND: Ischemia-Reperfusion (I/R) injury is the tissue damage that results from re-oxygenation of ischemic tissues. ...ME …
MitoQ alleviates hippocampal damage after cerebral ischemia: The potential role of SIRT6 in regulating mitochondrial dysfunction and neuroinflammation.
Ibrahim AA, Abdel Mageed SS, Safar MM, El-Yamany MF, Oraby MA. Ibrahim AA, et al. Life Sci. 2023 Sep 1;328:121895. doi: 10.1016/j.lfs.2023.121895. Epub 2023 Jun 27. Life Sci. 2023. PMID: 37385372
MitoQ (2 mg/kg; i.p daily) was administered for 7 successive days prior to the induction of brain ischemia. KEY FINDINGS: I/R rats exhibited hippocampal damage evidenced by aggravated mitochondrial oxidative stress, thereby enhancing mtROS and oxidized mtDNA, togeth …
MitoQ (2 mg/kg; i.p daily) was administered for 7 successive days prior to the induction of brain ischemia. KEY FINDINGS: I/R …
Protective effect of Naringin on experimental hindlimb ischemia/reperfusion injury in rats.
Gürsul C, Ekinci Akdemir FN, Akkoyun T, Can İ, Gül M, Gülçin İ. Gürsul C, et al. J Enzyme Inhib Med Chem. 2016;31(sup1):56-61. doi: 10.3109/14756366.2016.1167050. Epub 2016 Apr 7. J Enzyme Inhib Med Chem. 2016. PMID: 27052452
This study was designed to investigate the antioxidant effects of Naringin, in ischemia/reperfusion (I/R)-induced skeletal muscle injury in rats. The rats were randomly allocated into three groups including control, I/R and I/R + Naringin …
This study was designed to investigate the antioxidant effects of Naringin, in ischemia/reperfusion (I/R)-induced skeletal mus …
Dimethyl fumarate and curcumin attenuate hepatic ischemia/reperfusion injury via Nrf2/HO-1 activation and anti-inflammatory properties.
Ibrahim SG, El-Emam SZ, Mohamed EA, Abd Ellah MF. Ibrahim SG, et al. Int Immunopharmacol. 2020 Mar;80:106131. doi: 10.1016/j.intimp.2019.106131. Epub 2020 Jan 22. Int Immunopharmacol. 2020. PMID: 31981960
METHOD: To study potential protective effects of DMF with CUR against hepatic I/R injury in rats, animals were randomly allocated into seven groups as follows: (1) Sham; (2) DMF (25 mg/Kg, p.o); (3) CUR (400 mg/Kg, p.o.); (4) I/R; (5) DMF + I/ …
METHOD: To study potential protective effects of DMF with CUR against hepatic I/R injury in rats, animals were randomly alloca …
Diacerein protects rats with liver ischemia/reperfusion damage: Down-regulation of TLR4/ NFκ-B signaling pathway.
Ibrahim MA, Abdelzaher WY, Ibrahim YF, Ahmed AF, Welson NN, Al-Rashed S, Batiha GE, Abdel-Aziz AM. Ibrahim MA, et al. Biomed Pharmacother. 2021 Feb;134:111063. doi: 10.1016/j.biopha.2020.111063. Epub 2020 Dec 24. Biomed Pharmacother. 2021. PMID: 33348310 Free article.
PURPOSE: Liver ischemia-reperfusion (I/R) injury is an inescapable problem. Diacerein, a chondro-protective drug, has antioxidant and anti-inflammatory effects. ...METHODS: Adult male albino rats were assigned to 4 groups: sham group, diacerein pretreated sham group …
PURPOSE: Liver ischemia-reperfusion (I/R) injury is an inescapable problem. Diacerein, a chondro-protective drug, has antioxid …
Endothelial arginase 2 mediates retinal ischemia/reperfusion injury by inducing mitochondrial dysfunction.
Shosha E, Fouda AY, Lemtalsi T, Haigh S, Fulton D, Ibrahim A, Al-Shabrawey M, Caldwell RW, Caldwell RB. Shosha E, et al. Mol Metab. 2021 Nov;53:101273. doi: 10.1016/j.molmet.2021.101273. Epub 2021 Jun 15. Mol Metab. 2021. PMID: 34139341 Free PMC article.
METHODS: We used wild-type (WT), global A2 knockout (A2KO-) mice, cell-specific A2 knockout mice subjected to retinal ischemia/reperfusion (I/R), and bovine retinal endothelial cells (BRECs) subjected to an oxygen-glucose deprivation/reperfusion (OGD/R) insult. ...W …
METHODS: We used wild-type (WT), global A2 knockout (A2KO-) mice, cell-specific A2 knockout mice subjected to retinal ischemia/reperfusion ( …
Sex differences on multikinase inhibitors toxicity in patients with advanced gastroenteropancreatic neuroendocrine tumours.
Hernando J, Roca-Herrera M, García-Álvarez A, Raymond E, Ruszniewski P, Kulke MH, Grande E, García-Carbonero R, Castellano D, Salazar R, Ibrahim T, Teule A, Alonso V, Fazio N, Valle JW, Tafuto S, Carmona A, Navarro V, Capdevila J. Hernando J, et al. Eur J Cancer. 2023 Jul;188:39-48. doi: 10.1016/j.ejca.2023.04.013. Epub 2023 Apr 23. Eur J Cancer. 2023. PMID: 37196483 Free article.
Gender difference in the development of cardiac lesions following acute ischemic-reperfusion renal injury in albino rats.
Ibrahim IY, Elbassuoni EA, Ragy MM, Habeeb WN. Ibrahim IY, et al. Gen Physiol Biophys. 2013 Sep;32(3):421-8. doi: 10.4149/gpb_2013036. Epub 2013 Jul 12. Gen Physiol Biophys. 2013. PMID: 23846259
Renal ischemia-reperfusion (I/R) is the major cause of acute renal failure. Renal I/R have distant effects on other organs, especially the heart. The purpose of this study was to investigate cardiac lesion following bilateral renal ischemia (50 minutes …
Renal ischemia-reperfusion (I/R) is the major cause of acute renal failure. Renal I/R have distant effects on ot …
26 results