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Metabolism and toxicity of menthofuran in rat liver slices and in rats.
Chem Res Toxicol. 2010 Nov 15;23(11):1824-32. doi: 10.1021/tx100268g. Epub 2010 Oct 14.
Chem Res Toxicol. 2010.
PMID: 20945912
Free PMC article.
Evidence has been presented that p-cresol and other unusual oxidative products are metabolites of menthofuran in rats and that p-cresol may be responsible in part for the hepatotoxicity caused by menthofuran [ Madyastha, K. M. and Raj, C. P. (1992) Drug Metab …
Evidence has been presented that p-cresol and other unusual oxidative products are metabolites of menthofuran in rats and that p-cresol may …
Purification and partial characterization of caffeine oxidase--A novel enzyme from a mixed culture consortium.
Madyastha KM, Sridhar GR, Vadiraja BB, Madhavi YS.
Madyastha KM, et al.
Biochem Biophys Res Commun. 1999 Sep 24;263(2):460-4. doi: 10.1006/bbrc.1999.1401.
Biochem Biophys Res Commun. 1999.
PMID: 10491316
Dichlorophenol indophenol and cytochrome c served as good electron acceptors but NAD and NADP did not. Caffeine served as the best substrate with an apparent K(m) of 11.4 microM. various analogues of theobromine were also effective substrates for caffeine oxidase. . …
Dichlorophenol indophenol and cytochrome c served as good electron acceptors but NAD and NADP did not. Caffeine served as the best substrate …
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