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Year Number of Results
2000 1
2002 1
2003 1
2005 1
2006 1
2007 1
2008 1
2009 1
2010 2
2012 3
2013 1
2017 3
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2019 5
2020 2
2021 4
2022 8
2023 4
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39 results

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Page 1
Medicinal chemistry and properties of 1,2,4-thiadiazoles.
Tam TF, Leung-Toung R, Li W, Spino M, Karimian K. Tam TF, et al. Mini Rev Med Chem. 2005 Apr;5(4):367-79. doi: 10.2174/1389557053544056. Mini Rev Med Chem. 2005. PMID: 15853627 Review.
This review addresses the medicinal chemistry and various properties of 1,2,4-thiadiazoles in their potential as new electrophilic "warheads" for targeting the cysteine residues of biomolecules (e.g, H+/K+ ATPase), and cysteine-dependent enzymes (e.g., cathepsin B and tran …
This review addresses the medicinal chemistry and various properties of 1,2,4-thiadiazoles in their potential as new electrophilic "warheads …
Thiol-dependent enzymes and their inhibitors: a review.
Leung-Toung R, Li W, Tam TF, Karimian K. Leung-Toung R, et al. Curr Med Chem. 2002 May;9(9):979-1002. doi: 10.2174/0929867024606704. Curr Med Chem. 2002. PMID: 11966457 Review.
However, AG7088 (1) an inhibitor of rhinovirus-3C is in phase II/III clinical trial for the treatment of common cold and VX-740 (2, pralnacasan) an inhibitor of caspase-1 is in phase II clinical trial as an anti-inflammatory agent for rheumatoid arthritis. Several other cysteine …
However, AG7088 (1) an inhibitor of rhinovirus-3C is in phase II/III clinical trial for the treatment of common cold and VX-740 (2, pralnaca …
Antimony(V) Incorporation into Schwertmannite: Critical Insights on Antimony Retention in Acidic Environments.
Rastegari M, Karimian N, Johnston SG, Doherty SJ, Hamilton JL, Choppala G, Hosseinpour Moghaddam M, Burton ED. Rastegari M, et al. Environ Sci Technol. 2022 Dec 20;56(24):17776-17784. doi: 10.1021/acs.est.2c07341. Epub 2022 Nov 29. Environ Sci Technol. 2022. PMID: 36445713
Schwertmannite was synthesized from solutions containing a range of Sb(V)/Fe(III) ratios, and the resulting solids were investigated using geochemical analysis, powder X-ray diffraction (XRD), dissolution kinetic experiments, and extended X-ray absorption fine structure (EXAFS) s …
Schwertmannite was synthesized from solutions containing a range of Sb(V)/Fe(III) ratios, and the resulting solids were investigated using g …
An X-ray absorption spectroscopic study of the Fe(II)-induced transformation of Cr(VI)-substituted schwertmannite.
Choppala G, Karimian N, Burton ED. Choppala G, et al. J Hazard Mater. 2022 Jun 5;431:128580. doi: 10.1016/j.jhazmat.2022.128580. Epub 2022 Mar 3. J Hazard Mater. 2022. PMID: 35359110
Here, we investigate the Fe(II)-induced transformation of Cr(VI)-substituted schwertmannite as a function of pH (4-8) and the degree of Cr(VI) substitution (0.16-13 mol% Cr(VI)O(4)(2-)-for-SO(4)(2-) substitution). Iron K-edge EXAFS spectroscopy revealed that higher levels …
Here, we investigate the Fe(II)-induced transformation of Cr(VI)-substituted schwertmannite as a function of pH (4-8) and the degree of Cr(V …
Reductive transformation of birnessite and the mobility of co-associated antimony.
Karimian N, Johnston SG, Burton ED. Karimian N, et al. J Hazard Mater. 2021 Feb 15;404(Pt B):124227. doi: 10.1016/j.jhazmat.2020.124227. Epub 2020 Oct 10. J Hazard Mater. 2021. PMID: 33086181
In this study, we investigate Sb partitioning and speciation during anoxic incubation of Sb(V)-coprecipitated birnessite in the presence and absence of Mn(II)(aq) at pH 5.5 and 7.5. Antimony K-edge XANES spectroscopy revealed that Sb(V) persisted as the only solid-phase Sb …
In this study, we investigate Sb partitioning and speciation during anoxic incubation of Sb(V)-coprecipitated birnessite in the presence and …
Antimonate Controls Manganese(II)-Induced Transformation of Birnessite at a Circumneutral pH.
Karimian N, Hockmann K, Planer-Friedrich B, Johnston SG, Burton ED. Karimian N, et al. Environ Sci Technol. 2021 Jul 20;55(14):9854-9863. doi: 10.1021/acs.est.1c00916. Epub 2021 Jul 6. Environ Sci Technol. 2021. PMID: 34228928
The reaction of Mn(II) with birnessite enhanced Sb(V)(aq) removal compared to Mn(II)-free treatments. Antimony K-edge extended X-ray absorption fine structure (EXAFS) spectroscopy revealed that heterovalent substitution of Sb(V) for Mn(III) occurred within the secondary Mn …
The reaction of Mn(II) with birnessite enhanced Sb(V)(aq) removal compared to Mn(II)-free treatments. Antimony K-edge extended X-ray …
The Oxidative Status and Na(+)/K(+)-ATPase Activity in Obsessive-Compulsive Disorder: A Case Control Study.
Mohammadi AH, Balandeh E, Hasani J, Karimian M, Arabshahi V, Pourfarzam M, Bahmani F, Namazi G. Mohammadi AH, et al. Biomed Res Int. 2024 Feb 23;2024:9979582. doi: 10.1155/2024/9979582. eCollection 2024. Biomed Res Int. 2024. PMID: 38435539 Free PMC article.
MDA levels in serum and RBC membrane were measured using fluorometric method. Serum TAC level, serum GSH level, and Na(+)/K(+)-ATPase activity were also measured using spectrophotometric methods. ...There was significantly lower activity of erythrocyte membrane Na(+)/K …
MDA levels in serum and RBC membrane were measured using fluorometric method. Serum TAC level, serum GSH level, and Na(+)/K(+)-ATPase …
Molecularly imprinted electrochemical sensor for the ultrasensitive detection of cytochrome c.
Campagnol D, Karimian N, Paladin D, Rizzolio F, Ugo P. Campagnol D, et al. Bioelectrochemistry. 2022 Dec;148:108269. doi: 10.1016/j.bioelechem.2022.108269. Epub 2022 Sep 18. Bioelectrochemistry. 2022. PMID: 36179393
The partition isotherm obtained fits the Langmuir model, indicating a high affinity for Cyt c, with an association constant K(a) = 5 10 (11) M(-1). DPV measurements allow to achieve extremely high analytical sensitivity and low detection limit, in the femtomolar range, wit …
The partition isotherm obtained fits the Langmuir model, indicating a high affinity for Cyt c, with an association constant K(a) = 5 …
39 results