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Page 1
ZVex™, a dendritic-cell-tropic lentivector, primes protective antitumor T cell responses that are significantly boosted using heterologous vaccine modalities.
Vaccine. 2020 Sep 22;38(41):6367-6373. doi: 10.1016/j.vaccine.2020.08.003. Epub 2020 Aug 20.
Vaccine. 2020.
PMID: 32828576
Intratumoral expression of IL-12 from lentiviral or RNA vectors acts synergistically with TLR4 agonist (GLA) to generate anti-tumor immunological memory.
Leleux JA, Albershardt TC, Reeves R, James R, Krull J, Parsons AJ, Ter Meulen J, Berglund P.
Leleux JA, et al.
PLoS One. 2021 Dec 2;16(12):e0259301. doi: 10.1371/journal.pone.0259301. eCollection 2021.
PLoS One. 2021.
PMID: 34855754
Free PMC article.
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Biophysical Attributes of CpG Presentation Control TLR9 Signaling to Differentially Polarize Systemic Immune Responses.
Leleux JA, Pradhan P, Roy K.
Leleux JA, et al.
Cell Rep. 2017 Jan 17;18(3):700-710. doi: 10.1016/j.celrep.2016.12.073.
Cell Rep. 2017.
PMID: 28099848
Free article.
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Surface-Presentation of CpG and Protein-Antigen on Pathogen-Like Polymer Particles Generate Strong Prophylactic and Therapeutic Antitumor Protection.
Dawson E, Leleux JA, Pradhan P, Roy K.
Dawson E, et al. Among authors: leleux ja.
ACS Biomater Sci Eng. 2017 Feb 13;3(2):169-178. doi: 10.1021/acsbiomaterials.6b00384. Epub 2016 Sep 27.
ACS Biomater Sci Eng. 2017.
PMID: 33450793
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The effect of combined IL10 siRNA and CpG ODN as pathogen-mimicking microparticles on Th1/Th2 cytokine balance in dendritic cells and protective immunity against B cell lymphoma.
Pradhan P, Qin H, Leleux JA, Gwak D, Sakamaki I, Kwak LW, Roy K.
Pradhan P, et al. Among authors: leleux ja.
Biomaterials. 2014 Jul;35(21):5491-504. doi: 10.1016/j.biomaterials.2014.03.039. Epub 2014 Apr 8.
Biomaterials. 2014.
PMID: 24720881
Free PMC article.
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