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Page 1
New function of the myostatin/activin type I receptor (ALK4) as a mediator of muscle atrophy and muscle regeneration.
Pasteuning-Vuhman S, Boertje-van der Meulen JW, van Putten M, Overzier M, Ten Dijke P, Kiełbasa SM, Arindrarto W, Wolterbeek R, Lezhnina KV, Ozerov IV, Aliper AM, Hoogaars WM, Aartsma-Rus A, Loomans CJ. Pasteuning-Vuhman S, et al. Among authors: lezhnina kv. FASEB J. 2017 Jan;31(1):238-255. doi: 10.1096/fj.201600675R. Epub 2016 Oct 12. FASEB J. 2017. PMID: 27733450 Free PMC article.
Design of efficient computational workflows for in silico drug repurposing.
Vanhaelen Q, Mamoshina P, Aliper AM, Artemov A, Lezhnina K, Ozerov I, Labat I, Zhavoronkov A. Vanhaelen Q, et al. Among authors: lezhnina k. Drug Discov Today. 2017 Feb;22(2):210-222. doi: 10.1016/j.drudis.2016.09.019. Epub 2016 Sep 28. Drug Discov Today. 2017. PMID: 27693712 Review.
Data aggregation at the level of molecular pathways improves stability of experimental transcriptomic and proteomic data.
Borisov N, Suntsova M, Sorokin M, Garazha A, Kovalchuk O, Aliper A, Ilnitskaya E, Lezhnina K, Korzinkin M, Tkachev V, Saenko V, Saenko Y, Sokov DG, Gaifullin NM, Kashintsev K, Shirokorad V, Shabalina I, Zhavoronkov A, Mishra B, Cantor CR, Buzdin A. Borisov N, et al. Among authors: lezhnina k. Cell Cycle. 2017 Oct 2;16(19):1810-1823. doi: 10.1080/15384101.2017.1361068. Epub 2017 Aug 21. Cell Cycle. 2017. PMID: 28825872 Free PMC article.
In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development.
Ozerov IV, Lezhnina KV, Izumchenko E, Artemov AV, Medintsev S, Vanhaelen Q, Aliper A, Vijg J, Osipov AN, Labat I, West MD, Buzdin A, Cantor CR, Nikolsky Y, Borisov N, Irincheeva I, Khokhlovich E, Sidransky D, Camargo ML, Zhavoronkov A. Ozerov IV, et al. Among authors: lezhnina kv. Nat Commun. 2016 Nov 16;7:13427. doi: 10.1038/ncomms13427. Nat Commun. 2016. PMID: 27848968 Free PMC article.
In silico analysis of pathways activation landscape in oral squamous cell carcinoma and oral leukoplakia.
Makarev E, Schubert AD, Kanherkar RR, London N, Teka M, Ozerov I, Lezhnina K, Bedi A, Ravi R, Mehra R, Hoque MO, Sloma I, Gaykalova DA, Csoka AB, Sidransky D, Zhavoronkov A, Izumchenko E. Makarev E, et al. Among authors: lezhnina k. Cell Death Discov. 2017 May 22;3:17022. doi: 10.1038/cddiscovery.2017.22. eCollection 2017. Cell Death Discov. 2017. PMID: 28580171 Free PMC article.