Design, synthesis, biological evaluation, and molecular modeling studies of pyrazole-benzofuran hybrids as new α-glucosidase inhibitor.
Azimi F, Azizian H, Najafi M, Khodarahmi G, Saghaei L, Hassanzadeh M, Ghasemi JB, Faramarzi MA, Larijani B, Hassanzadeh F, Mahdavi M.
Azimi F, et al.
Sci Rep. 2021 Oct 21;11(1):20776. doi: 10.1038/s41598-021-99899-1.
Sci Rep. 2021.
PMID: 34675367
Free PMC article.
Newly identified inhibitors were found to be four to eighteen folds more active with IC(50) values in the range of 40.6 0.2-164.3 1.8 M, as compared to the standard drug acarbose (IC(50) = 750.0 10.0 muM). ...
Newly identified inhibitors were found to be four to eighteen folds more active with IC(50) values in the range of 40.6 0.2-164.3 1.8 M …