CYP2J2∗7 Genotype Predicts Risk of Chemotherapy-Induced Hematologic Toxicity and Reduced Relative Dose Intensity in Ethiopian Breast Cancer Patients.
Ahmed JH, Makonnen E, Yimer G, Seifu D, Bekele A, Assefa M, Aseffa A, Howe R, Fotoohi A, Hassan M, Aklillu E.
Ahmed JH, et al.
Front Pharmacol. 2019 May 14;10:481. doi: 10.3389/fphar.2019.00481. eCollection 2019.
Front Pharmacol. 2019.
PMID: 31139078
Free PMC article.
Higher risk of reduced RDI was associated with CYP2J2()7 allele [Adjusted odds ratio (AOR) = 2.79; 95% CI = 1.21-6.46], BMI 18.4 kg/m(2) (AOR = 5.98; 95% CI = 1.36-26.23), baseline grade 1 leukopenia (AOR = 6.09; 95% CI = 1.24-29.98), and baseline neutropenia (AOR = 3.37; …
Higher risk of reduced RDI was associated with CYP2J2()7 allele [Adjusted odds ratio (AOR) = 2.79; 95% CI = 1.21-6.46], BMI 18.4 kg/m …