TRPM7 kinase is required for insulin production and compensatory islet responses during obesity.
Khajavi N, Beck A, Riçku K, Beyerle P, Jacob K, Syamsul SF, Belkacemi A, Reinach PS, Schreier PC, Salah H, Popp T, Novikoff A, Breit A, Chubanov V, Müller TD, Zierler S, Gudermann T.
Khajavi N, et al.
JCI Insight. 2023 Feb 8;8(3):e163397. doi: 10.1172/jci.insight.163397.
JCI Insight. 2023.
PMID: 36574297
Free PMC article.
Therefore, regulatory pathways that promote beta cell compensation are potential targets for treatment of diabetes. The transient receptor potential cation channel subfamily M member 7 protein (TRPM7), harboring a cation channel and a serine/threonine kinase, has been impl …
Therefore, regulatory pathways that promote beta cell compensation are potential targets for treatment of diabetes. The transient receptor p …