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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1975 2
1976 1
1977 7
1978 2
1979 1
1980 2
1981 4
1982 4
1983 2
1984 6
1985 5
1986 5
1987 6
1988 5
1989 8
1990 8
1991 9
1992 14
1993 15
1994 12
1995 18
1996 17
1997 18
1998 24
1999 26
2000 15
2001 34
2002 24
2003 32
2004 39
2005 31
2006 30
2007 29
2008 24
2009 33
2010 35
2011 43
2012 52
2013 48
2014 40
2015 66
2016 67
2017 69
2018 86
2019 111
2020 123
2021 139
2022 143
2023 145
2024 55

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1,568 results

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Page 1
Twin-Arginine Protein Translocation.
Goosens VJ, van Dijl JM. Goosens VJ, et al. Curr Top Microbiol Immunol. 2017;404:69-94. doi: 10.1007/82_2016_7. Curr Top Microbiol Immunol. 2017. PMID: 27121927 Review.
We provide overviews of our current understanding of Tat pathway composition and mechanistic aspects related to Tat-dependent cargo protein translocation. ...Tat pathways of several Gram-positive bacteria are discussed in detail, with emphasis on the Tat …
We provide overviews of our current understanding of Tat pathway composition and mechanistic aspects related to Tat-dependent …
Transport of Folded Proteins by the Tat System.
Frain KM, Robinson C, van Dijl JM. Frain KM, et al. Protein J. 2019 Aug;38(4):377-388. doi: 10.1007/s10930-019-09859-y. Protein J. 2019. PMID: 31401776 Free PMC article. Review.
The twin-arginine protein translocation (Tat) system has been characterized in bacteria, archaea and the chloroplast thylakoidal membrane. ...In particular, we address features of twin-arginine signal peptides, the essential Tat components and how they assemble into …
The twin-arginine protein translocation (Tat) system has been characterized in bacteria, archaea and the chloroplast thylakoidal memb …
Novel Tat-Dependent Protein Secretion.
Braun V, Hantke K. Braun V, et al. J Bacteriol. 2020 Apr 9;202(9):e00058-20. doi: 10.1128/JB.00058-20. Print 2020 Apr 9. J Bacteriol. 2020. PMID: 32015148 Free PMC article.
The transcription initiation signal elicited by the binding of ferric citrate to the outer membrane FecA protein is transmitted by the FecR protein across the cytoplasmic membrane to the FecI extracytoplasmic function (ECF) sigma factor. In this issue of Journal of Bacteriology, …
The transcription initiation signal elicited by the binding of ferric citrate to the outer membrane FecA protein is transmitted by the FecR …
Functional roles of HIV-1 Tat protein in the nucleus.
Musinova YR, Sheval EV, Dib C, Germini D, Vassetzky YS. Musinova YR, et al. Cell Mol Life Sci. 2016 Feb;73(3):589-601. doi: 10.1007/s00018-015-2077-x. Epub 2015 Oct 27. Cell Mol Life Sci. 2016. PMID: 26507246 Review.
Tat can modulate cellular processes by interacting with different cellular structures and signaling pathways. In the nucleus, Tat might be localized either in the nucleoplasm or the nucleolus depending on its concentration. ...
Tat can modulate cellular processes by interacting with different cellular structures and signaling pathways. In the nucleus, Tat …
The Tat system of Gram-positive bacteria.
Goosens VJ, Monteferrante CG, van Dijl JM. Goosens VJ, et al. Biochim Biophys Acta. 2014 Aug;1843(8):1698-706. doi: 10.1016/j.bbamcr.2013.10.008. Epub 2013 Oct 16. Biochim Biophys Acta. 2014. PMID: 24140208 Free article. Review.
This review provides an overview of the current understanding of the Tat system with specific focus on Gram-positive bacteria. The 'universal minimal Tat system' is composed of a TatA and a TatC protein. ...Further, an overview of specific Gram-positive bacterial …
This review provides an overview of the current understanding of the Tat system with specific focus on Gram-positive bacteria. The 'u …
The Tat protein transport system: intriguing questions and conundrums.
Hamsanathan S, Musser SM. Hamsanathan S, et al. FEMS Microbiol Lett. 2018 Jun 1;365(12):fny123. doi: 10.1093/femsle/fny123. FEMS Microbiol Lett. 2018. PMID: 29897510 Free PMC article. Review.
The Tat machinery catalyzes the transport of folded proteins across the cytoplasmic membrane in bacteria and the thylakoid membrane in plants. ...This presents a fundamental and major challenge, namely, that the Tat system catalyzes the movement of large folded prot …
The Tat machinery catalyzes the transport of folded proteins across the cytoplasmic membrane in bacteria and the thylakoid membrane i …
GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca(2+) nanoparticles underlies distinct gene therapy effect in ovarian cancer.
Su L, Sun Z, Qi F, Su H, Qian L, Li J, Zuo L, Huang J, Yu Z, Li J, Chen Z, Zhang S. Su L, et al. J Nanobiotechnology. 2022 Jul 20;20(1):340. doi: 10.1186/s12951-022-01530-6. J Nanobiotechnology. 2022. PMID: 35858873 Free PMC article.
Practice of tumor-targeted suicide gene therapy is hampered by unsafe and low efficient delivery of plasmid DNA (pDNA). Using HIV-Tat-derived peptide (Tat) to non-covalently form Tat/pDNA complexes advances the delivery performance. ...Formulated Tat/p …
Practice of tumor-targeted suicide gene therapy is hampered by unsafe and low efficient delivery of plasmid DNA (pDNA). Using HIV-Tat …
HIV-1 Tat and cocaine coexposure impacts piRNAs to affect astrocyte energy metabolism.
Doke M, Kashanchi F, Khan MA, Samikkannu T. Doke M, et al. Epigenomics. 2022 Mar;14(5):261-278. doi: 10.2217/epi-2021-0252. Epub 2022 Feb 16. Epigenomics. 2022. PMID: 35170353 Free PMC article.
Materials & methods: We used small RNA sequencing analysis to investigate the impacts of HIV-1 Tat and cocaine coexposure on the expression of piRNAs in human primary astrocytes. Results: We identified 27,700 piRNAs and analyzed them by small RNA next-generation sequen …
Materials & methods: We used small RNA sequencing analysis to investigate the impacts of HIV-1 Tat and cocaine coexposure on the …
Targeting Tat-TAR RNA Interaction for HIV-1 Inhibition.
Alanazi A, Ivanov A, Kumari N, Lin X, Wang S, Kovalskyy D, Nekhai S. Alanazi A, et al. Viruses. 2021 Oct 6;13(10):2004. doi: 10.3390/v13102004. Viruses. 2021. PMID: 34696435 Free PMC article.
Only the T0516-4834 compound showed selective inhibition of Tat-induced HIV-1 transcription, whereas the T6780107 compound inhibited equally basal and Tat-induced transcription and the T5628834 compound only inhibited basal HIV-1 transcription. ...Of the three compo …
Only the T0516-4834 compound showed selective inhibition of Tat-induced HIV-1 transcription, whereas the T6780107 compound inhibited …
Role of Host Factors on the Regulation of Tat-Mediated HIV-1 Transcription.
Mousseau G, Valente ST. Mousseau G, et al. Curr Pharm Des. 2017;23(28):4079-4090. doi: 10.2174/1381612823666170622104355. Curr Pharm Des. 2017. PMID: 28641539 Free PMC article. Review.
BACKGROUND: The viral transactivator Tat protein is a key modulator of HIV-1 replication, as it regulates transcriptional elongation from the integrated proviral genome. ...By means of a complex set of interactions with host cellular factors, Tat determines the fate …
BACKGROUND: The viral transactivator Tat protein is a key modulator of HIV-1 replication, as it regulates transcriptional elongation …
1,568 results