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Cardiovascular Efficacy and Safety of Bococizumab in High-Risk Patients.
Ridker PM, Revkin J, Amarenco P, Brunell R, Curto M, Civeira F, Flather M, Glynn RJ, Gregoire J, Jukema JW, Karpov Y, Kastelein JJP, Koenig W, Lorenzatti A, Manga P, Masiukiewicz U, Miller M, Mosterd A, Murin J, Nicolau JC, Nissen S, Ponikowski P, Santos RD, Schwartz PF, Soran H, White H, Wright RS, Vrablik M, Yunis C, Shear CL, Tardif JC; SPIRE Cardiovascular Outcome Investigators. Ridker PM, et al. N Engl J Med. 2017 Apr 20;376(16):1527-1539. doi: 10.1056/NEJMoa1701488. Epub 2017 Mar 17. N Engl J Med. 2017. PMID: 28304242 Free article. Clinical Trial.
Molecular binding interaction of pyridinium based gemini surfactants with bovine serum albumin: Insights from physicochemical, multispectroscopic, and computational analysis.
Aslam J, Hussain Lone I, Ansari F, Aslam A, Aslam R, Akram M. Aslam J, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2021 Apr 5;250:119350. doi: 10.1016/j.saa.2020.119350. Epub 2020 Dec 22. Spectrochim Acta A Mol Biomol Spectrosc. 2021. PMID: 33387804
Steady-state fluorescence analysis evaluates the structural alterations of BSA with the addition of m-Py-m GS. The plots of Stern-Volmer, modified Stern-Volmer, and thermodynamic parameters were used to determine the binding type of m-Py-m GS to BSA. . …
Steady-state fluorescence analysis evaluates the structural alterations of BSA with the addition of m-Py-m GS. The plots of St …
Biophysical investigation of the interaction between cationic biodegradable C(m)-E2O-C(m) gemini surfactants and porcine serum albumin (PSA).
Akram M, Ansari F, Kabir-Ud-Din. Akram M, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2019 Jan 5;206:520-528. doi: 10.1016/j.saa.2018.08.043. Epub 2018 Aug 27. Spectrochim Acta A Mol Biomol Spectrosc. 2019. PMID: 30176428
The interaction of porcine serum albumin (PSA) with biodegradable, less cytotoxic C(m)-E2O-C(m) gemini surfactants was monitored using state-of-the-art techniques. ...These results indicate that the cationic C(m)-E2O-C(m) geminis, at lower concentratio …
The interaction of porcine serum albumin (PSA) with biodegradable, less cytotoxic C(m)-E2O-C(m) gemini surfactants was monitor …
Electronic structures, bonding aspects and spectroscopic parameters of homo/hetero valent bridged dinuclear transition metal complexes.
Yadav O, Ansari M, Ansari A. Yadav O, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2022 Oct 5;278:121331. doi: 10.1016/j.saa.2022.121331. Epub 2022 May 5. Spectrochim Acta A Mol Biomol Spectrosc. 2022. PMID: 35597159
Considering the same, here first time we report DFT study on bridged non-heme metal complexes based on N-Et-HPTB ligand system containing homovalent (M(II)M(II)); {[(Mn(II))(2)(O(2)CCH(3))(N-Et-HPTB)](2+); Species I), [(Fe(II))(2)(O(2)CCH(3))(N-Et-HPTB)](2+); Specie …
Considering the same, here first time we report DFT study on bridged non-heme metal complexes based on N-Et-HPTB ligand system containing ho …
An evaluation of spectral and statistical parameters of ion pair complexation of Zafirlukast using chromogenic dyes in solid dispersion-based formulations.
Masood Z, Ansari MT, Afzal S, Farooq M, Adnan S, Aslam N. Masood Z, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2023 Dec 5;302:123049. doi: 10.1016/j.saa.2023.123049. Epub 2023 Jun 19. Spectrochim Acta A Mol Biomol Spectrosc. 2023. PMID: 37356388
Four simple, extraction-free, fast, and economical methods based on charge transfer complexation among nitrogen of ZST with sulfonyl group comprising chromogenic mediator bromophenol blue (BPB-Method B), bromothymol blue (BTB-Method C) and bromocresol green (BCG-Method D). The fi …
Four simple, extraction-free, fast, and economical methods based on charge transfer complexation among nitrogen of ZST with sulfonyl group c …
Specificity landscapes of DNA binding molecules elucidate biological function.
Carlson CD, Warren CL, Hauschild KE, Ozers MS, Qadir N, Bhimsaria D, Lee Y, Cerrina F, Ansari AZ. Carlson CD, et al. Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4544-9. doi: 10.1073/pnas.0914023107. Epub 2010 Feb 22. Proc Natl Acad Sci U S A. 2010. PMID: 20176964 Free PMC article.
Outcome of laparoscopic sleeve gastrectomy with and without staple line oversewing in morbidly obese patients: a randomized study.
Aggarwal S, Sharma AP, Ramaswamy N. Aggarwal S, et al. J Laparoendosc Adv Surg Tech A. 2013 Nov;23(11):895-9. doi: 10.1089/lap.2013.0137. Epub 2013 Sep 28. J Laparoendosc Adv Surg Tech A. 2013. PMID: 24073838 Clinical Trial.
Indications for this procedure were morbidly obese (body mass index 40 kg/m(2)) or severely obese (body mass index 35 kg/m(2)) patients with comorbidities including type 2 diabetes mellitus, hypertension, sleep apnea, and osteoarthritis. ...
Indications for this procedure were morbidly obese (body mass index 40 kg/m(2)) or severely obese (body mass index 35 kg/m(2)) …
Synthesis and spectroscopic characterization of magnetic hydroxyapatite nanocomposite using ultrasonic irradiation.
Gopi D, Ansari MT, Shinyjoy E, Kavitha L. Gopi D, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2012 Feb 15;87:245-50. doi: 10.1016/j.saa.2011.11.047. Epub 2011 Nov 28. Spectrochim Acta A Mol Biomol Spectrosc. 2012. PMID: 22177219
The vibrating sample magnetometer curve exhibits the super paramagnetic property of the samples and the saturation magnetization (M(s)) value of the functionalized magnetic hydroxyapatite. The M(s) value is found to be much less than that of pure magnetite nanoparti …
The vibrating sample magnetometer curve exhibits the super paramagnetic property of the samples and the saturation magnetization (M(s …
Insight into the molecular interaction between the anticancer drug, enzalutamide and human alpha-2-macroglobulin: Biochemical and biophysical approach.
Khalid Zia M, Siddiqui T, Ansari S, Muaz M, Ahsan H, Halim Khan F. Khalid Zia M, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2024 Apr 15;311:123957. doi: 10.1016/j.saa.2024.123957. Epub 2024 Jan 26. Spectrochim Acta A Mol Biomol Spectrosc. 2024. PMID: 38310741
The secondary structure of alpha(2)M was slightly altered by enzalutamide according to far UV-CD spectral analysis. ...The ITC reiterated the exothermic and spontaneous nature of the interaction. The lower proteinase inhibitory activity of the alpha(2)M-enzalutamide …
The secondary structure of alpha(2)M was slightly altered by enzalutamide according to far UV-CD spectral analysis. ...The ITC reiter …
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