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Page 1
Prospective evaluation of the efficacy, safety, and optimal biomarker enrichment strategy for nangibotide, a TREM-1 inhibitor, in patients with septic shock (ASTONISH): a double-blind, randomised, controlled, phase 2b trial.
François B, Lambden S, Fivez T, Gibot S, Derive M, Grouin JM, Salcedo-Magguilli M, Lemarié J, De Schryver N, Jalkanen V, Hicheur T, Garaud JJ, Cuvier V, Ferrer R, Bestle M, Pettilä V, Mira JP, Bouisse C, Mercier E, Vermassen J, Huberlant V, Vinatier I, Anguel N, Levy M, Laterre PF; ASTONISH investigators. François B, et al. Lancet Respir Med. 2023 Oct;11(10):894-904. doi: 10.1016/S2213-2600(23)00158-3. Epub 2023 May 31. Lancet Respir Med. 2023. PMID: 37269870 Clinical Trial.
Comparison of Three Expanded-Spectrum Cephalosporin Hydrolysis Assays and the NG-Test CTX-M Multi Assay That Detects All CTX-M-Like Enzymes.
Gonzalez C, Moguet C, Chalin A, Oueslati S, Dortet L, Simon S, Volland H, Naas T. Gonzalez C, et al. Diagnostics (Basel). 2022 Jan 14;12(1):197. doi: 10.3390/diagnostics12010197. Diagnostics (Basel). 2022. PMID: 35054364 Free PMC article.
Here, we have evaluated three biochemical ESC hydrolysis assays (ESBL NDP test, beta-LACTA test, LFIA-CTX assay) and the NG-Test() CTX-M MULTI that detects CTX-M enzymes, on 93 well-characterized Gram-negative isolates, including 60 Enterobacterales, 21 Pseudomonas …
Here, we have evaluated three biochemical ESC hydrolysis assays (ESBL NDP test, beta-LACTA test, LFIA-CTX assay) and the NG-Test() CTX-M …
To Be or Not to Be an OXA-48 Carbapenemase.
Dabos L, Oueslati S, Bernabeu S, Bonnin RA, Dortet L, Naas T. Dabos L, et al. Microorganisms. 2022 Jan 24;10(2):258. doi: 10.3390/microorganisms10020258. Microorganisms. 2022. PMID: 35208713 Free PMC article.
With this aim, the coefficient of activity for imipenem (k(cat)/K(m)) was determined for a total of 30 enzymes, including OXA-48, OXA-48-like natural variants, and OXA-48 synthetic mutants. ...
With this aim, the coefficient of activity for imipenem (k(cat)/K(m)) was determined for a total of 30 enzymes, including OXA-48, OXA …
A Lateral Flow Immunoassay for the Rapid Identification of CTX-M-Producing Enterobacterales from Culture Plates and Positive Blood Cultures.
Bernabeu S, Ratnam KC, Boutal H, Gonzalez C, Vogel A, Devilliers K, Plaisance M, Oueslati S, Malhotra-Kumar S, Dortet L, Fortineau N, Simon S, Volland H, Naas T. Bernabeu S, et al. Diagnostics (Basel). 2020 Sep 28;10(10):764. doi: 10.3390/diagnostics10100764. Diagnostics (Basel). 2020. PMID: 32998433 Free PMC article.
We have developed a lateral flow immunoassay (LFIA), named NG-Test CTX-M MULTI (NG-Test), to detect group 1, 2, 8, 9, 25 CTX-M producers from agar plates and from positive blood cultures in less than 15 min. ...Among the 100 positive blood cultures with GNB tested 1 …
We have developed a lateral flow immunoassay (LFIA), named NG-Test CTX-M MULTI (NG-Test), to detect group 1, 2, 8, 9, 25 CTX-M …
Lactobacillus plantarum alleviate aflatoxins (B(1) and M(1)) induced disturbances in the intestinal genes expression and DNA fragmentation in mice.
Jebali R, Ben Salah-Abbès J, Abbès S, Hassan AM, Abdel-Aziem SH, El-Nekeety AA, Oueslati R, Abdel-Wahhab MA. Jebali R, et al. Toxicon. 2018 May;146:13-23. doi: 10.1016/j.toxicon.2018.03.008. Epub 2018 Mar 21. Toxicon. 2018. PMID: 29574215
This study aimed to assess the disturbances in intestinal genes expression and DNA fragmentation in mice treated orally with aflatoxin B(1) (AFB(1)) or aflatoxin M(1) (AFM(1)) and the protective activity of Lactobacillus plantarum (LP). ...
This study aimed to assess the disturbances in intestinal genes expression and DNA fragmentation in mice treated orally with aflatoxin B(1) …
Evaluation of the EasyScreen™ ESBL/CPO Detection Kit for the Detection of ß-Lactam Resistance Genes.
Gonzalez C, Oueslati S, Biez L, Dortet L, Naas T. Gonzalez C, et al. Diagnostics (Basel). 2022 Sep 14;12(9):2223. doi: 10.3390/diagnostics12092223. Diagnostics (Basel). 2022. PMID: 36140624 Free PMC article.
We have evaluated a novel real-time PCR assay using fluorescent probes and 3base() technology, the EasyScreen(TM) ESBL/CPO Detection Kit (Genetic Signatures, Newtown, Australia), for the detection of 15 beta-lactamase genes (bla(VIM), bla(NDM), bla(IMP), bla(OXA-48), bla(KPC), bl …
We have evaluated a novel real-time PCR assay using fluorescent probes and 3base() technology, the EasyScreen(TM) ESBL/CPO Detection Kit (Ge …
[Cardiac abnormalities associated with hyperthyroidism: clinical, structural and rhythmic study].
Yazidi M, Ezzaouia K, Madhi W, Oueslati I, Ouarda F, Murali S, Chihaoui M. Yazidi M, et al. Ann Cardiol Angeiol (Paris). 2023 Apr;72(2):101579. doi: 10.1016/j.ancard.2022.11.014. Epub 2022 Dec 19. Ann Cardiol Angeiol (Paris). 2023. PMID: 36543712 French.
RESULTS: The mean age of the patients was 44.8 14.4 years. The sex ratio (M/F) was 0.3. Five patients (17%) had subclinical hyperthyroidism and 25 (83%) had overt hyperthyroidism. ...
RESULTS: The mean age of the patients was 44.8 14.4 years. The sex ratio (M/F) was 0.3. Five patients (17%) had subclinical hyperthyr …
Development and validation of a lateral flow immunoassay for rapid detection of VanA-producing enterococci.
Oueslati S, Volland H, Cattoir V, Bernabeu S, Girlich D, Dulac D, Plaisance M, Laroche M, Dortet L, Simon S, Naas T. Oueslati S, et al. J Antimicrob Chemother. 2021 Jan 1;76(1):146-151. doi: 10.1093/jac/dkaa413. J Antimicrob Chemother. 2021. PMID: 33305802
No cross-reaction was observed with any other clinically relevant ligases (VanB, C1, C2, D, E, G, L, M and N). Overall, the sensitivity and specificity of the assay were 100% for VanA-VRE grown on MH agar plates. ...
No cross-reaction was observed with any other clinically relevant ligases (VanB, C1, C2, D, E, G, L, M and N). Overall, the sensitivi …
45 results