New classes of carbazoles as potential multi-functional anti-Alzheimer's agents.
Choubdar N, Golshani M, Jalili-Baleh L, Nadri H, Küçükkilinç TT, Ayazgök B, Moradi A, Moghadam FH, Abdolahi Z, Ameri A, Salehian F, Foroumadi A, Khoobi M.
Choubdar N, et al.
Bioorg Chem. 2019 Oct;91:103164. doi: 10.1016/j.bioorg.2019.103164. Epub 2019 Jul 29.
Bioorg Chem. 2019.
PMID: 31398601
In the present study, we synthesized a series of compounds comprising the carbazole backbone linked to the benzyl piperazine, benzyl piperidine, pyridine, quinoline, or isoquinoline moiety through an aliphatic linker and evaluated as cholinesterase inhibitors. The synthesized com …
In the present study, we synthesized a series of compounds comprising the carbazole backbone linked to the benzyl piperazine, benzyl piperid …