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Page 1
Pharmacological fingerprint of antipsychotic drugs at the serotonin 5-HT2A receptor.
Gaitonde SA, Avet C, de la Fuente Revenga M, Blondel-Tepaz E, Shahraki A, Pastor AM, Talagayev V, Robledo P, Kolb P, Selent J, González-Maeso J, Bouvier M. Gaitonde SA, et al. Mol Psychiatry. 2024 Sep;29(9):2753-2764. doi: 10.1038/s41380-024-02531-7. Epub 2024 Apr 2. Mol Psychiatry. 2024. PMID: 38561467 Free PMC article.
An Updated Review on Implications of Autophagy and Apoptosis in Tumorigenesis: Possible Alterations in Autophagy through Engineered Nanomaterials and Their Importance in Cancer Therapy.
Ghaznavi H, Shirvaliloo M, Zarebkohan A, Shams Z, Radnia F, Bahmanpour Z, Sargazi S, Saravani R, Shirvalilou S, Shahraki O, Shahraki S, Nazarlou Z, Sheervalilou R. Ghaznavi H, et al. Mol Pharmacol. 2021 Aug;100(2):119-143. doi: 10.1124/molpharm.121.000234. Epub 2021 May 14. Mol Pharmacol. 2021. PMID: 33990406 Review.
8-Alkylmercaptocaffeine derivatives: antioxidant, molecular docking, and in-vitro cytotoxicity studies.
Sargazi S, Shahraki S, Shahraki O, Zargari F, Sheervalilou R, Maghsoudi S, Soltani Rad MN, Saravani R. Sargazi S, et al. Bioorg Chem. 2021 Jun;111:104900. doi: 10.1016/j.bioorg.2021.104900. Epub 2021 Apr 9. Bioorg Chem. 2021. PMID: 33894429

Among the twelve synthesized derivatives, three compounds (C1, C5, and C7) bearing propyl, heptyl, and 3-methyl-butyl moieties showed higher and more desirable cytotoxic activity against all the studied cell lines (IC(50) < 100 M). Furthermore, C5 synergistically enhanc

…
Among the twelve synthesized derivatives, three compounds (C1, C5, and C7) bearing propyl, heptyl, and 3-methyl-butyl moieties showed higher …
Hormetic effects of curcumin on oxidative stress injury induced by trivalent arsenic in isolated rat hepatocytes.
Amirmostofian M, Akbari F, Hashemzaei M, Safaeinejad F, Tabrizian K, Arbab H, Rezaee R, Hemat Jouy S, Ghorani V, Shahraki J. Amirmostofian M, et al. Avicenna J Phytomed. 2023 Nov-Dec;13(6):641-650. doi: 10.22038/AJP.2023.22634. Avicenna J Phytomed. 2023. PMID: 38106636 Free PMC article.
The EC(50) concentration of As(3+) was used in toxicity assessments and curcumin (2, 5, and 10 M) was added 15 min before As(3+) addition to isolated hepatocytes. Curcumin impact was assessed in terms of cytotoxicity, lipid peroxidation induction, reactive oxygen species ( …
The EC(50) concentration of As(3+) was used in toxicity assessments and curcumin (2, 5, and 10 M) was added 15 min before As(3+) addi …
Intrahippocampal co-administration of nicotine and O-acetyl-L-carnitine prevents the H-89-induced spatial learning deficits in Morris water maze.
Hashemzaei M, Baratzadeh N, Shahramian I, Fanoudi S, Sanati M, Rezaei H, Shahraki J, Rezaee R, Belaran M, Bazi A, Tabrizian K. Hashemzaei M, et al. J Complement Integr Med. 2021 May 10;19(3):691-696. doi: 10.1515/jcim-2021-0035. eCollection 2022 Sep 1. J Complement Integr Med. 2021. PMID: 33964190
METHODS: Spatial memory impairment was induced by the bilateral intrahippocampal administration of 10 M H-89 (dissolved in dimethyl sulfoxide, DMSO) to rats. The rats then received bilateral administrations of either nicotine (1 mug/muL, dissolved in saline) or O-acetyl-L- …
METHODS: Spatial memory impairment was induced by the bilateral intrahippocampal administration of 10 M H-89 (dissolved in dimethyl s …
49 results