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Page 1
T-cell exhaustion induced by continuous bispecific molecule exposure is ameliorated by treatment-free intervals.
Philipp N, Kazerani M, Nicholls A, Vick B, Wulf J, Straub T, Scheurer M, Muth A, Hänel G, Nixdorf D, Sponheimer M, Ohlmeyer M, Lacher SM, Brauchle B, Marcinek A, Rohrbacher L, Leutbecher A, Rejeski K, Weigert O, von Bergwelt-Baildon M, Theurich S, Kischel R, Jeremias I, Bücklein V, Subklewe M. Philipp N, et al. Among authors: kazerani m. Blood. 2022 Sep 8;140(10):1104-1118. doi: 10.1182/blood.2022015956. Blood. 2022. PMID: 35878001 Free PMC article.
TNF-α and IFN-γ differentially regulate AML cell susceptibility to CD70-antibody-mediated cytotoxicity.
Sponheimer M, White K, Ulrich M, Kazerani M, Maiser A, Tyborski ET, Rappa GP, Richter D, Briem E, Hänel G, Philipp N, Nixdorf D, Rohrbacher L, Marcinek A, Linder A, Kuhl N, Piseddu I, Straub T, Harz H, Wichmann C, Maenner D, Rudelius M, Hornung V, Leonhardt H, Van Elssen CHMJ, Abdelhamed S, Diolaiti D, Bücklein V, Subklewe M. Sponheimer M, et al. Among authors: kazerani m. J Immunother Cancer. 2025 Dec 4;13(12):e013024. doi: 10.1136/jitc-2025-013024. J Immunother Cancer. 2025. PMID: 41344992 Free PMC article.
FLT3-directed BiTE molecules vs CAR T cells in AML: costimulatory signals mitigate T-cell exhaustion.
Rohrbacher L, Nixdorf D, Stadler H, Brauchle B, Märkl F, Gottschlich A, Hoffmann GV, Philipp N, Hänel G, Kirmaier ME, Marcinek A, Kazerani M, Richter D, Magno G, Goldstein RL, Theurich S, Straub T, Kobold S, Arvedson T, Bücklein V, Subklewe M. Rohrbacher L, et al. Among authors: kazerani m. Blood Adv. 2026 Feb 24;10(4):1179-1193. doi: 10.1182/bloodadvances.2025018168. Blood Adv. 2026. PMID: 41324594 Free PMC article.
TP53 deficiency in AML induces resistance to T-cell engagers through an immunosuppressive secretome.
Winter L, Pawlowsky L, Muth A, Neumann AS, White K, Kazerani M, Nixdorf D, Brauchle B, Rohrbacher L, Hänel G, Petrera A, Briem E, Hoffmann GV, Janert T, Carlini E, Gottschlich A, Spiekermann K, Straub T, Kischel R, Kobold S, Andreeff M, Buecklein VL, Subklewe M. Winter L, et al. Among authors: kazerani m. Leukemia. 2026 Jun 1. doi: 10.1038/s41375-026-02991-6. Online ahead of print. Leukemia. 2026. PMID: 42225967
Pre-vaccine immune profiling in cancer patients identifies correlates of COVID-19 vaccine responses.
Kazerani M, Mahov S, Foley J, Merin NM, Choi SY, Lownik J, Xu AM, Milshteyn L, Villamejor AL, Nadri M, Nguyen N, Kazemian E, Hamid O, Darrah J, Gong J, Paquette R, Vescio R, Mehmi I, Tourtellotte WG, Ramanujan VK, Reckamp KL, Figueiredo JC, Merchant A. Kazerani M, et al. Hum Vaccin Immunother. 2025 Dec;21(1):2599622. doi: 10.1080/21645515.2025.2599622. Epub 2025 Dec 15. Hum Vaccin Immunother. 2025. PMID: 41399253 Free PMC article.
Evolution of T-cell fitness through AML progression: enhanced bispecific T-cell engager-mediated function of bone marrow T cells at remission compared to initial diagnosis and relapse.
Kazerani M, Marcinek A, Philipp N, Brauchle B, Taylor JJ, Moreno HD, Terrasi A, Tast B, Rohrbacher L, Wang Y, Warm M, Emhardt AJ, Magno G, Spiekermann K, Herold T, Straub T, Theurich S, Schotta G, Kischel R, Bücklein VL, Subklewe M. Kazerani M, et al. Leukemia. 2024 Oct;38(10):2270-2275. doi: 10.1038/s41375-024-02387-4. Epub 2024 Aug 22. Leukemia. 2024. PMID: 39174782 Free PMC article. No abstract available.
12 results