Screening in planarians identifies MORN2 as a key component in LC3-associated phagocytosis and resistance to bacterial infection.
Abnave P, Mottola G, Gimenez G, Boucherit N, Trouplin V, Torre C, Conti F, Ben Amara A, Lepolard C, Djian B, Hamaoui D, Mettouchi A, Kumar A, Pagnotta S, Bonatti S, Lepidi H, Salvetti A, Abi-Rached L, Lemichez E, Mege JL, Ghigo E.
Abnave P, et al.
Cell Host Microbe. 2014 Sep 10;16(3):338-50. doi: 10.1016/j.chom.2014.08.002.
Cell Host Microbe. 2014.
PMID: 25211076
Free article.
Whole-transcriptome analysis coupled with RNAi screening of worms infected with Staphylococcus aureus or Legionella pneumophila identified 18 resistance genes with nine human orthologs, of which we examined the function of MORN2. Human MORN2 facilitates phagocytosis …
Whole-transcriptome analysis coupled with RNAi screening of worms infected with Staphylococcus aureus or Legionella pneumophila identified 1 …