Relevance of lysine snorkeling in the outer transmembrane domain of small viral potassium ion channels.
Gebhardt M, Henkes LM, Tayefeh S, Hertel B, Greiner T, Van Etten JL, Baumeister D, Cosentino C, Moroni A, Kast SM, Thiel G.
Gebhardt M, et al.
Biochemistry. 2012 Jul 17;51(28):5571-9. doi: 10.1021/bi3006016. Epub 2012 Jul 6.
Biochemistry. 2012.
PMID: 22734656
Two similar channels, Kcv(ATCV-1) and Kcv(MT325), lack a cytosolic N-terminus, and neutralization of their equivalent cationic amino acids inhibits their function. To understand the variable importance of the cationic amino acids, we reanalyzed molecular dynamics simulatio …
Two similar channels, Kcv(ATCV-1) and Kcv(MT325), lack a cytosolic N-terminus, and neutralization of their equivalent cationic amino …