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Laminin α1 reduces muscular dystrophy in dy2J mice.
Gawlik KI, Harandi VM, Cheong RY, Petersén Å, Durbeej M. Gawlik KI, et al. Among authors: harandi vm. Matrix Biol. 2018 Sep;70:36-49. doi: 10.1016/j.matbio.2018.02.024. Epub 2018 Mar 12. Matrix Biol. 2018. PMID: 29544677
Hence, we have generated dy(2J)/dy(2J) mice (that express a substantial amount of an N-terminal truncated laminin alpha2 chain) overexpressing laminin alpha1 chain in the neuromuscular system. ...
Hence, we have generated dy(2J)/dy(2J) mice (that express a substantial amount of an N-terminal truncated laminin alpha2 chain) overe …
Antioxidants Reduce Muscular Dystrophy in the dy2J/dy2J Mouse Model of Laminin α2 Chain-Deficient Muscular Dystrophy.
Harandi VM, Oliveira BMS, Allamand V, Friberg A, Fontes-Oliveira CC, Durbeej M. Harandi VM, et al. Antioxidants (Basel). 2020 Mar 18;9(3):244. doi: 10.3390/antiox9030244. Antioxidants (Basel). 2020. PMID: 32197453 Free PMC article.
Reactive oxygen species (ROS) increase when oxygen homeostasis is not maintained and, here, we investigate whether oxidative stress indeed is involved in the pathogenesis of LAMA2-CMD. We also analyze the effects of two antioxidant molecules, N-acetyl-L-cysteine (NAC) and …
Reactive oxygen species (ROS) increase when oxygen homeostasis is not maintained and, here, we investigate whether oxidative stress indeed i …