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Alzheimer's disease drug development pipeline: 2022.
Cummings J, Lee G, Nahed P, Kambar MEZN, Zhong K, Fonseca J, Taghva K. Cummings J, et al. Alzheimers Dement (N Y). 2022 May 4;8(1):e12295. doi: 10.1002/trc2.12295. eCollection 2022. Alzheimers Dement (N Y). 2022. PMID: 35516416 Free PMC article. Review.
Wearable knee health system employing novel physiological biomarkers.
Inan OT, Whittingslow DC, Teague CN, Hersek S, Pouyan MB, Millard-Stafford M, Kogler GF, Sawka MN. Inan OT, et al. J Appl Physiol (1985). 2018 Mar 1;124(3):537-547. doi: 10.1152/japplphysiol.00366.2017. Epub 2017 Jul 27. J Appl Physiol (1985). 2018. PMID: 28751371 Free PMC article. Review.
Polyglycerol for Half-Life Extension of Proteins-Alternative to PEGylation?
Tully M, Dimde M, Weise C, Pouyan P, Licha K, Schirner M, Haag R. Tully M, et al. Biomacromolecules. 2021 Apr 12;22(4):1406-1416. doi: 10.1021/acs.biomac.0c01627. Epub 2021 Apr 1. Biomacromolecules. 2021. PMID: 33792290
In this study, we introduce polyglycerol (PG) of different lengths and architectures (linear and hyperbranched) as an alternative polymer platform to poly(ethylene glycol) (PEG) for half-life extension (HLE). We designed site-selective N-terminally modified PG-protein conj …
In this study, we introduce polyglycerol (PG) of different lengths and architectures (linear and hyperbranched) as an alternative polymer pl …