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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 1
2004 7
2005 9
2006 10
2007 8
2008 8
2009 9
2010 10
2011 11
2012 11
2013 15
2014 11
2015 10
2016 16
2017 18
2018 19
2019 26
2020 21
2021 13
2022 8
2023 2
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218 results
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Page 1
Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2.
Klemm T, Ebert G, Calleja DJ, Allison CC, Richardson LW, Bernardini JP, Lu BG, Kuchel NW, Grohmann C, Shibata Y, Gan ZY, Cooney JP, Doerflinger M, Au AE, Blackmore TR, van der Heden van Noort GJ, Geurink PP, Ovaa H, Newman J, Riboldi-Tunnicliffe A, Czabotar PE, Mitchell JP, Feltham R, Lechtenberg BC, Lowes KN, Dewson G, Pellegrini M, Lessene G, Komander D. Klemm T, et al. Among authors: ovaa h. EMBO J. 2020 Sep 15;39(18):e106275. doi: 10.15252/embj.2020106275. Epub 2020 Aug 26. EMBO J. 2020. PMID: 32845033 Free PMC article.
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity.
Shin D, Mukherjee R, Grewe D, Bojkova D, Baek K, Bhattacharya A, Schulz L, Widera M, Mehdipour AR, Tascher G, Geurink PP, Wilhelm A, van der Heden van Noort GJ, Ovaa H, Müller S, Knobeloch KP, Rajalingam K, Schulman BA, Cinatl J, Hummer G, Ciesek S, Dikic I. Shin D, et al. Among authors: ovaa h. Nature. 2020 Nov;587(7835):657-662. doi: 10.1038/s41586-020-2601-5. Epub 2020 Jul 29. Nature. 2020. PMID: 32726803 Free PMC article.
Tools to investigate the ubiquitin proteasome system.
Leestemaker Y, Ovaa H. Leestemaker Y, et al. Among authors: ovaa h. Drug Discov Today Technol. 2017 Dec;26:25-31. doi: 10.1016/j.ddtec.2017.11.006. Epub 2017 Nov 26. Drug Discov Today Technol. 2017. PMID: 29249239 Free article. Review.
Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Horn-Ghetko D, Krist DT, Prabu JR, Baek K, Mulder MPC, Klügel M, Scott DC, Ovaa H, Kleiger G, Schulman BA. Horn-Ghetko D, et al. Among authors: ovaa h. Nature. 2021 Feb;590(7847):671-676. doi: 10.1038/s41586-021-03197-9. Epub 2021 Feb 3. Nature. 2021. PMID: 33536622 Free PMC article.
Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer's Disease Neurons.
van der Kant R, Langness VF, Herrera CM, Williams DA, Fong LK, Leestemaker Y, Steenvoorden E, Rynearson KD, Brouwers JF, Helms JB, Ovaa H, Giera M, Wagner SL, Bang AG, Goldstein LSB. van der Kant R, et al. Among authors: ovaa h. Cell Stem Cell. 2019 Mar 7;24(3):363-375.e9. doi: 10.1016/j.stem.2018.12.013. Epub 2019 Jan 24. Cell Stem Cell. 2019. PMID: 30686764 Free PMC article.
Ubiquitin Phosphorylation at Thr12 Modulates the DNA Damage Response.
Walser F, Mulder MPC, Bragantini B, Burger S, Gubser T, Gatti M, Botuyan MV, Villa A, Altmeyer M, Neri D, Ovaa H, Mer G, Penengo L. Walser F, et al. Among authors: ovaa h. Mol Cell. 2020 Nov 5;80(3):423-436.e9. doi: 10.1016/j.molcel.2020.09.017. Epub 2020 Oct 5. Mol Cell. 2020. PMID: 33022275 Free PMC article.
Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis.
Liu S, González-Prieto R, Zhang M, Geurink PP, Kooij R, Iyengar PV, van Dinther M, Bos E, Zhang X, Le Dévédec SE, van de Water B, Koning RI, Zhu HJ, Mesker WE, Vertegaal ACO, Ovaa H, Zhang L, Martens JWM, Ten Dijke P. Liu S, et al. Among authors: ovaa h. Clin Cancer Res. 2020 Mar 15;26(6):1460-1473. doi: 10.1158/1078-0432.CCR-19-1373. Epub 2019 Dec 19. Clin Cancer Res. 2020. PMID: 31857432 Free PMC article.
Editorial: Probing the Ubiquitin Landscape.
Mulder MPC, Zhuang Z, Liu L, Kessler BM, Ovaa H. Mulder MPC, et al. Among authors: ovaa h. Front Chem. 2020 May 20;8:449. doi: 10.3389/fchem.2020.00449. eCollection 2020. Front Chem. 2020. PMID: 32509738 Free PMC article. No abstract available.
218 results