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The studies which reported 2016 liver transplant recipients with de novo DSAs showed an increased complication risk, i.e. graft loss and chronic rejection (OR 3.61; 95% CI 1.94-6.71, P < 0.001; I(2) 58.19%), and allograft rejection alone (OR 6.43; 95% CI: 3.17-13.04;
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