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109 results

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Page 1
Catalytic role of the amino-terminal proline in 4-oxalocrotonate tautomerase: affinity labeling and heteronuclear NMR studies.
Stivers JT, Abeygunawardana C, Mildvan AS, Hajipour G, Whitman CP, Chen LH. Stivers JT, et al. Biochemistry. 1996 Jan 23;35(3):803-13. doi: 10.1021/bi951077g. Biochemistry. 1996. PMID: 8547260
Finally, the pH dependence of kinact/KI for affinity labeling by 3-BP yields a pKa value of 6.7 +/- 0.3, in reasonable agreement with the pKa values found for kcat/KM for the non-sticky substrate 2-hydroxy-2,4-pentadienoate and by direct NMR titration of Pro-1 [Stivers, J. T., Ab …
Finally, the pH dependence of kinact/KI for affinity labeling by 3-BP yields a pKa value of 6.7 +/- 0.3, in reasonable agreement with the pK …
Administration of growth hormone ameliorates adverse effects of total sleep deprivation.
Arvin P, Ghafouri S, Bavarsad K, Hajipour S, Khoshnam SE, Sarkaki A, Farbood Y. Arvin P, et al. Metab Brain Dis. 2023 Jun;38(5):1671-1681. doi: 10.1007/s11011-023-01192-9. Epub 2023 Mar 2. Metab Brain Dis. 2023. PMID: 36862276

The concentrations of serum corticotropin-releasing hormone (CRH) (p < 0.001) and hippocampal interleukin-6 (IL-6) (p < 0.001) increased. ...Treatment of TSD rats with GH improved motor balance (p < 0.001) and locomotion (p < 0.001), decrea

The concentrations of serum corticotropin-releasing hormone (CRH) (p < 0.001) and hippocampal interleukin-6 (IL-6) (p <

Development of a Thalassemia International Prognostic Scoring System (TIPSS).
Vitrano A, Musallam KM, Meloni A, Karimi M, Daar S, Ricchi P, Costantini S, Vlachaki E, Di Marco V, El-Beshlawy A, Hajipour M, Ansari SH, Filosa A, Ceci A, Singer ST, Naserullah ZA, Pepe A, Cademartiri F, Pollina SA, Scondotto S, Dardanoni G, Bonifazi F, Sankaran VG, Vichinsky E, Taher AT, Maggio A; International Working Group on Thalassemia (IWG-THAL). Vitrano A, et al. Blood Cells Mol Dis. 2023 Mar;99:102710. doi: 10.1016/j.bcmd.2022.102710. Epub 2022 Nov 25. Blood Cells Mol Dis. 2023. PMID: 36463683 Review.

The TIPSS score was a good predictor for the outcome of death in the validation dataset (AUC: 0.722, 95%CI: 0.641-0.804) and survival was significantly different between patients in the three risk categories (P < 0.001). Compared to low-risk patients, the hazard ratio f

The TIPSS score was a good predictor for the outcome of death in the validation dataset (AUC: 0.722, 95%CI: 0.641-0.804) and survival was si …
cis pT231-Tau Drives Neurodegeneration in Bipolar Disorder.
Naserkhaki R, Zamanzadeh S, Baharvand H, Nabavi SM, Pakdaman H, Shahbazi S, Vosough M, Ghaedi G, Barzegar A, Mirtorabi D, Hedayatshodeh M, Ehsani E, Falahati M, Hajipour MJ, Shahpasand K. Naserkhaki R, et al. ACS Chem Neurosci. 2019 Mar 20;10(3):1214-1221. doi: 10.1021/acschemneuro.8b00629. Epub 2019 Jan 23. ACS Chem Neurosci. 2019. PMID: 30644730
We found an increase in cis p-tau levels as well as viability decrease in the cell model. Furthermore, we discovered that lithium treatment inhibits cis p-tau formation, resulting in diminished cell death. We also examined BD and healthy human brain samples and dete …
We found an increase in cis p-tau levels as well as viability decrease in the cell model. Furthermore, we discovered that lithium tre …
Molecular interaction of fibrinogen with zeolite nanoparticles.
Derakhshankhah H, Hosseini A, Taghavi F, Jafari S, Lotfabadi A, Ejtehadi MR, Shahbazi S, Fattahi A, Ghasemi A, Barzegari E, Evini M, Saboury AA, Shahri SMK, Ghaemi B, Ng EP, Awala H, Omrani F, Nabipour I, Raoufi M, Dinarvand R, Shahpasand K, Mintova S, Hajipour MJ, Mahmoudi M. Derakhshankhah H, et al. Sci Rep. 2019 Feb 7;9(1):1558. doi: 10.1038/s41598-018-37621-4. Sci Rep. 2019. PMID: 30733474 Free PMC article.
Chronic meningitis in adults: a comparison between neurotuberculosis and neurobrucellosis.
Shirazinia M, Sheybani F, Naderi H, Haddad M, Hajipour P, Khoroushi F. Shirazinia M, et al. BMC Infect Dis. 2024 Apr 25;24(1):441. doi: 10.1186/s12879-024-09345-6. BMC Infect Dis. 2024. PMID: 38664652 Free PMC article.
Cerebrospinal fluid (CSF) analysis revealed a significantly higher percentage of polymorphonuclear leukocytes (PMN) in TBM compared to BM (Standardized mean difference: 0.69, 95% CI: 0.18 to 1.20, P-value: 0.008). Neuroimaging findings indicated higher risks of hydrocephal …
Cerebrospinal fluid (CSF) analysis revealed a significantly higher percentage of polymorphonuclear leukocytes (PMN) in TBM compared to BM (S …
Hypoxic Burden Based on Automatically Identified Desaturations Is Associated with Adverse Health Outcomes.
Esmaeili N, Labarca G, Hu WH, Vena D, Messineo L, Gell L, Hajipour M, Taranto-Montemurro L, Sands SA, Redline S, Wellman A, Sehhati M, Azarbarzin A. Esmaeili N, et al. Ann Am Thorac Soc. 2023 Nov;20(11):1633-1641. doi: 10.1513/AnnalsATS.202303-248OC. Ann Am Thorac Soc. 2023. PMID: 37531573

Results: The Spearman's rank correlation between HB (median [interquartile range], 34.4 [18.4-59.8] % min/h) and HB(Oxi) (median [interquartile range], 34.5 [21.6-53.8] % min/h) was 0.81 (P < 0.001). Similar to HB, HB(Oxi) was significantly associated with EDS (aOR [95%

Results: The Spearman's rank correlation between HB (median [interquartile range], 34.4 [18.4-59.8] % min/h) and HB(Oxi) (median [interquart …
Effects of mutations of the active site arginine residues in 4-oxalocrotonate tautomerase on the pKa values of active site residues and on the pH dependence of catalysis.
Czerwinski RM, Harris TK, Johnson WH Jr, Legler PM, Stivers JT, Mildvan AS, Whitman CP. Czerwinski RM, et al. Biochemistry. 1999 Sep 21;38(38):12358-66. doi: 10.1021/bi9911177. Biochemistry. 1999. PMID: 10493803
The unusually low pK(a) value of the general base catalyst Pro-1 (pK(a) = 6.4) in 4-oxalocrotonate tautomerase (4-OT) has been ascribed to both a low dielectric constant at the active site and the proximity of the cationic residues Arg-11 and Arg-39 [Stivers, J. T., Abeygunawarda …
The unusually low pK(a) value of the general base catalyst Pro-1 (pK(a) = 6.4) in 4-oxalocrotonate tautomerase (4-OT) has been ascribed to b …
The Role of Tumor Necrosis Factor-α (TNF-α) Polymorphisms in Gastric Cancer: a Meta-Analysis.
Gholamalizadeh M, Mirzaei Dahka S, Sedigh Ebrahim-Saraie H, Akbari ME, Pourtaheri A, Rastgoo S, Hajipour A, Shafaghi A, Doaei S, Kalantari N. Gholamalizadeh M, et al. J Gastrointest Cancer. 2022 Sep;53(3):756-769. doi: 10.1007/s12029-021-00688-w. Epub 2021 Sep 3. J Gastrointest Cancer. 2022. PMID: 34478034
The study revealed a significant association for TNF-alpha 308 (recessive model: OR = 0.646, P = 0.035), TNF-alpha-1031 (homozygote model: OR = 1.584, P = 0.027), and TNF-alpha-857 (homozygote model: OR = 1.760, P = 0.001) polymorphisms with the GC risk. The …
The study revealed a significant association for TNF-alpha 308 (recessive model: OR = 0.646, P = 0.035), TNF-alpha-1031 (homozygote m …
Associations between the dietary inflammatory index with obesity and body fat in male adolescents.
Gholamalizadeh M, Ahmadzadeh M, BourBour F, Vahid F, Ajami M, Majidi N, Hajipour A, Doaei S, Kalantari N, Alizadeh A, Jarrahi AM. Gholamalizadeh M, et al. BMC Endocr Disord. 2022 May 2;22(1):115. doi: 10.1186/s12902-022-01001-x. BMC Endocr Disord. 2022. PMID: 35501761 Free PMC article.

RESULTS: Participants with higher BF% ( 19.2%) had higher BMI (P < 0.001), DII, and intake of saturated fatty acids (SFAs), compared with the participants with lower BF%. Participants with a lower DII had significantly higher intakes of fibers (P < 0.001) and

RESULTS: Participants with higher BF% ( 19.2%) had higher BMI (P < 0.001), DII, and intake of saturated fatty acids (SFAs), compar

109 results