Insights Into The Effects of Amino Acid Substitutions on The Stability of Reteplase Structure: A Molecular Dynamics Simulation Study.
Haji-Allahverdipoor K, Jalali Javaran M, Rashidi Monfared S, Khadem-Erfan MB, Nikkhoo B, Bahrami Rad Z, Eslami H, Nasseri S.
Haji-Allahverdipoor K, et al. Among authors: rashidi monfared s.
Iran J Biotechnol. 2023 Jan 1;21(1):e3175. doi: 10.30498/ijb.2022.308798.3175. eCollection 2023 Jan.
Iran J Biotechnol. 2023.
PMID: 36811105
Free PMC article.
It is known that the application of reteplase is limited by the complex production processes and protein's stability challenges. Computational redesign of proteins has gained momentum in recent years, particularly as a powerful tool for improving protein stability and cons …
It is known that the application of reteplase is limited by the complex production processes and protein's stability challenges. Comp …