Carotenoids as potential inhibitors of TNFα in COVID-19 treatment.
Taghipour F, Motamed N, Amoozegar MA, Shahhoseini M, Mahdian S.
Taghipour F, et al.
PLoS One. 2022 Dec 27;17(12):e0276538. doi: 10.1371/journal.pone.0276538. eCollection 2022.
PLoS One. 2022.
PMID: 36574379
Free PMC article.
A total of 125 carotenoids were selected out of 1204 natural molecules, based on their pharmacokinetics properties and they all met Lipinski's rule of five. Among them, Sorgomol, Strigol and Orobanchol had the most favorable deltaG with the best ADME (absorption, distribut …
A total of 125 carotenoids were selected out of 1204 natural molecules, based on their pharmacokinetics properties and they all met Lipinski …