Mas-Related G-Protein Coupled Receptors and Cowhage-Induced Itch.
Reddy VB, Azimi E, Chu L, Lerner EA.
Reddy VB, et al.
J Invest Dermatol. 2018 Feb;138(2):461-464. doi: 10.1016/j.jid.2017.05.042. Epub 2017 Oct 4.
J Invest Dermatol. 2018.
PMID: 28988117
Free PMC article.
As serine proteases can activate members of the protease-activated receptor (PAR) family to induce itch and pain, the mechanism of action of mucunain and cathepsin S, a human cysteine protease, were likewise thought to be through activation of PARs. ...
As serine proteases can activate members of the protease-activated receptor (PAR) family to induce itch and pain, the mechanism of action of …