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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
1990 2
1991 1
1992 3
1993 2
1994 1
1997 2
1998 1
1999 3
2000 5
2001 9
2002 11
2003 11
2004 14
2005 11
2006 18
2007 24
2008 29
2009 34
2010 29
2011 49
2012 55
2013 58
2014 97
2015 132
2016 90
2017 68
2018 96
2019 116
2020 134
2021 180
2022 191
2023 142
2024 35

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1,441 results

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Page 1
Human PD-1 agonist treatment alleviates neutrophilic asthma by reprogramming T cells.
Helou DG, Quach C, Fung M, Painter JD, Hurrell BP, Eddie Loh YH, Howard E, Shafiei-Jahani P, Soroosh P, Sharpe AH, Akbari O. Helou DG, et al. J Allergy Clin Immunol. 2023 Feb;151(2):526-538.e8. doi: 10.1016/j.jaci.2022.07.022. Epub 2022 Aug 11. J Allergy Clin Immunol. 2023. PMID: 35963455 Free PMC article.
Programmed cell death protein-1 (PD-1) is a key homeostatic modulator of the immune response for T-cell effector functions. OBJECTIVE: We sought to investigate the role of PD-1 in the regulation of acute neutrophilic inflammation in a murine model of airway hyperreactivity …
Programmed cell death protein-1 (PD-1) is a key homeostatic modulator of the immune response for T-cell effector functions. OBJECTIVE …
CAR T cells: Living HIV drugs.
Namdari H, Rezaei F, Teymoori-Rad M, Mortezagholi S, Sadeghi A, Akbari A. Namdari H, et al. Rev Med Virol. 2020 Nov;30(6):1-14. doi: 10.1002/rmv.2139. Epub 2020 Jul 26. Rev Med Virol. 2020. PMID: 32713110 Review.
Chimeric antigen receptor (CAR) cell therapy has provided new opportunities for HIV treatment. Engineering T cells or hematopoietic stem cells (HSCs) to generate CAR T cells is a rapidly growing approach to develop an efficient immune cell to fight HIV. Herein, we r …
Chimeric antigen receptor (CAR) cell therapy has provided new opportunities for HIV treatment. Engineering T cells or hematopoietic s …
Epigenetic strategies to boost CAR T cell therapy.
Akbari B, Ghahri-Saremi N, Soltantoyeh T, Hadjati J, Ghassemi S, Mirzaei HR. Akbari B, et al. Mol Ther. 2021 Sep 1;29(9):2640-2659. doi: 10.1016/j.ymthe.2021.08.003. Epub 2021 Aug 6. Mol Ther. 2021. PMID: 34365035 Free PMC article. Review.
Chimeric antigen receptor (CAR) T cell therapy has led to a paradigm shift in cancer immunotherapy, but still several obstacles limit CAR T cell efficacy in cancers. ...We also offer our perspective on how selected epigenetic modifications can boost CAR T cel …
Chimeric antigen receptor (CAR) T cell therapy has led to a paradigm shift in cancer immunotherapy, but still several obstacles limit …
Metabolic and epigenetic orchestration of (CAR) T cell fate and function.
Akbari B, Hosseini Z, Shahabinejad P, Ghassemi S, Mirzaei HR, O'Connor RS. Akbari B, et al. Cancer Lett. 2022 Dec 1;550:215948. doi: 10.1016/j.canlet.2022.215948. Epub 2022 Oct 7. Cancer Lett. 2022. PMID: 36209973 Review.
Longevity, functionality, and metabolic fitness are key determinants of chimeric antigen receptor (CAR) T cell efficacy. Activated T cells follow an ordered differentiation program which is facilitated by metabolic adaptations. In response to antigen, T cells …
Longevity, functionality, and metabolic fitness are key determinants of chimeric antigen receptor (CAR) T cell efficacy. Activated …
PD-1 pathway regulates ILC2 metabolism and PD-1 agonist treatment ameliorates airway hyperreactivity.
Helou DG, Shafiei-Jahani P, Lo R, Howard E, Hurrell BP, Galle-Treger L, Painter JD, Lewis G, Soroosh P, Sharpe AH, Akbari O. Helou DG, et al. Nat Commun. 2020 Aug 10;11(1):3998. doi: 10.1038/s41467-020-17813-1. Nat Commun. 2020. PMID: 32778730 Free PMC article.
Allergic asthma is a leading chronic disease associated with airway hyperreactivity (AHR). Type-2 innate lymphoid cells (ILC2s) are a potent source of T-helper 2 (Th2) cytokines that promote AHR and lung inflammation. ...
Allergic asthma is a leading chronic disease associated with airway hyperreactivity (AHR). Type-2 innate lymphoid cells (ILC2s) are a potent …
Directing CAR T cells towards the tumor vasculature for the treatment of solid tumors.
Akbari P, Katsarou A, Daghighian R, van Mil LWHG, Huijbers EJM, Griffioen AW, van Beijnum JR. Akbari P, et al. Biochim Biophys Acta Rev Cancer. 2022 May;1877(3):188701. doi: 10.1016/j.bbcan.2022.188701. Epub 2022 Feb 22. Biochim Biophys Acta Rev Cancer. 2022. PMID: 35202772 Free article. Review.
For successful application of chimeric antigen receptor (CAR) T cell therapy in solid tumors, major hurdles have to be overcome. ...In this review, we discuss recent advances in CAR T cell therapy against solid tumors, with a focus on targeting the tumor vasculature …
For successful application of chimeric antigen receptor (CAR) T cell therapy in solid tumors, major hurdles have to be overcome. ...I …
Fear of missing out (FoMO) and internet use: A comprehensive systematic review and meta-analysis.
Akbari M, Seydavi M, Palmieri S, Mansueto G, Caselli G, Spada MM. Akbari M, et al. J Behav Addict. 2021 Dec 17;10(4):879-900. doi: 10.1556/2006.2021.00083. Online ahead of print. J Behav Addict. 2021. PMID: 34935633 Free PMC article. Review.
DISCUSSION AND CONCLUSIONS: FoMO demonstrates a considerable role in internet use; however, there is no evidence of interaction or bi-directional association between the mentioned. Overall, we still don't know what factors contribute to individuals exhibiting distinct patt …
DISCUSSION AND CONCLUSIONS: FoMO demonstrates a considerable role in internet use; however, there is no evidence of interaction or bi-direct …
PGE2-EP2/EP4 signaling elicits mesoCAR T cell immunosuppression in pancreatic cancer.
Akbari B, Soltantoyeh T, Shahosseini Z, Jadidi-Niaragh F, Hadjati J, Brown CE, Mirzaei HR. Akbari B, et al. Front Immunol. 2023 Jun 30;14:1209572. doi: 10.3389/fimmu.2023.1209572. eCollection 2023. Front Immunol. 2023. PMID: 37457723 Free PMC article.
Through our in vitro study, we manufactured fully human functional mesoCAR T cells specific for pancreatic cancer and investigated the influence of PGE2-EP2/EP4 signaling on proliferation, cytotoxicity, and cytokine production of mesoCAR T cells against pancreatic c …
Through our in vitro study, we manufactured fully human functional mesoCAR T cells specific for pancreatic cancer and investigated th …
1,441 results