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Page 1
Did you mean horton b[au] (358 results)?
Mutational scanning of TnpB reveals latent activity for genome editing.
Thornton BW, Weissman RF, Rodriguez JE, Tran RV, Duong BT, Terrace CI, Nagalakshmi U, Austin G, Groover ED, Wang FZ, Park JU, Georgieva V, Tartaglia J, Cho MJ, Dinesh-Kumar SP, Doudna JA, Savage DF. Thornton BW, et al. bioRxiv [Preprint]. 2025 Oct 30:2025.02.11.637750. doi: 10.1101/2025.02.11.637750. bioRxiv. 2025. PMID: 39990302 Free PMC article. Preprint.
Rapid DNA unwinding accelerates genome editing by engineered CRISPR-Cas9.
Eggers AR, Chen K, Soczek KM, Tuck OT, Doherty EE, Xu B, Trinidad MI, Thornton BW, Yoon PH, Doudna JA. Eggers AR, et al. Among authors: thornton bw. Cell. 2024 Jun 20;187(13):3249-3261.e14. doi: 10.1016/j.cell.2024.04.031. Epub 2024 May 22. Cell. 2024. PMID: 38781968 Free PMC article.
Stepwise DNA unwinding gates TnpB genome-editing activity.
Zhou Z, Saffarian-Deemyad I, Shi H, Weiss T, Ur-Rehman MM, Vohra K, Skopintsev P, Yoon PH, Trinidad MI, Langeberg CJ, Kamalu M, Amerasekera J, Doherty EE, Aris KDP, Al-Sayyad N, Thornton BW, Weissman RF, Wasko KM, Esain-Garcia I, DeTurk EC, Savage DF, Jacobsen SE, Bryant Z, Doudna JA. Zhou Z, et al. Among authors: thornton bw. bioRxiv [Preprint]. 2026 Jan 9:2026.01.09.698545. doi: 10.64898/2026.01.09.698545. bioRxiv. 2026. Update in: Mol Cell. 2026 Aug 5:S1097-2765(26)00501-0. doi: 10.1016/j.molcel.2026.07.015. PMID: 41542533 Free PMC article. Updated. Preprint.
Crisis psychopharmacology techniques.
Thornton WE, Thornton BP. Thornton WE, et al. Among authors: thornton bp. Dis Nerv Syst. 1974 Jan;35(1):32-4. Dis Nerv Syst. 1974. PMID: 17894053 Review.
Broad-spectrum enzymatic inhibition of CRISPR-Cas12a.
Knott GJ, Thornton BW, Lobba MJ, Liu JJ, Al-Shayeb B, Watters KE, Doudna JA. Knott GJ, et al. Among authors: thornton bw. Nat Struct Mol Biol. 2019 Apr;26(4):315-321. doi: 10.1038/s41594-019-0208-z. Epub 2019 Apr 1. Nat Struct Mol Biol. 2019. PMID: 30936531 Free PMC article.
Accelerated RNA detection using tandem CRISPR nucleases.
Liu TY, Knott GJ, Smock DCJ, Desmarais JJ, Son S, Bhuiya A, Jakhanwal S, Prywes N, Agrawal S, Díaz de León Derby M, Switz NA, Armstrong M, Harris AR, Charles EJ, Thornton BW, Fozouni P, Shu J, Stephens SI, Kumar GR, Zhao C, Mok A, Iavarone AT, Escajeda AM, McIntosh R, Kim S, Dugan EJ; IGI Testing Consortium; Pollard KS, Tan MX, Ott M, Fletcher DA, Lareau LF, Hsu PD, Savage DF, Doudna JA. Liu TY, et al. Among authors: thornton bw. Nat Chem Biol. 2021 Sep;17(9):982-988. doi: 10.1038/s41589-021-00842-2. Epub 2021 Aug 5. Nat Chem Biol. 2021. PMID: 34354262 Free PMC article.
Stepwise DNA-unwinding gates TnpB genome-editing activity.
Zhou Z, Saffarian-Deemyad I, Shi H, Weiss T, Ur-Rehman MM, Vohra K, Skopintsev P, Yoon PH, Trinidad MI, Langeberg CJ, Kamalu M, Amerasekera J, Zhou Y, Doherty EE, Aris KDP, Al-Sayyad N, Thornton BW, Weissman RF, Wasko KM, Esain-Garcia I, DeTurk EC, Savage DF, Jacobsen SE, Bryant Z, Doudna JA. Zhou Z, et al. Among authors: thornton bw. Mol Cell. 2026 Aug 5:S1097-2765(26)00501-0. doi: 10.1016/j.molcel.2026.07.015. Online ahead of print. Mol Cell. 2026. PMID: 42556347
216 results