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Year Number of Results
1993 1
1998 1
2002 1
2003 1
2004 1
2006 2
2007 1
2009 1
2010 1
2011 1
2013 1
2016 1
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2020 2
2021 1
2024 0

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Is a hydrophobic amino acid required to maintain the reactive V conformation of thiamin at the active center of thiamin diphosphate-requiring enzymes? Experimental and computational studies of isoleucine 415 of yeast pyruvate decarboxylase.
Guo F, Zhang D, Kahyaoglu A, Farid RS, Jordan F. Guo F, et al. Biochemistry. 1998 Sep 22;37(38):13379-91. doi: 10.1021/bi9807097. Biochemistry. 1998. PMID: 9748345
The residue I415 in pyruvate decarboxylase from Saccharomyces cerevisiae was substituted with a variety of uncharged side chains of varying steric requirements to test the hypothesis that this residue is responsible for supporting the V coenzyme conformation reported for t …
The residue I415 in pyruvate decarboxylase from Saccharomyces cerevisiae was substituted with a variety of uncharged side chains of varying …
Factors Affecting Prognosis and Survival in Extremity Osteosarcoma.
Dharanikota A, Arjunan R, Dasappa A. Dharanikota A, et al. Indian J Surg Oncol. 2021 Mar;12(1):199-206. doi: 10.1007/s13193-020-01277-2. Epub 2021 Jan 6. Indian J Surg Oncol. 2021. PMID: 33814854 Free PMC article.
Survival analysis was done using Kaplan-Meier method. p < 0.05 by log-rank test was considered statistically significant. Statistical data were analyzed using SPSS v.25(IBM). RESULTS: The median age of presentation was 18 years with male sex preponderance. ...

Survival analysis was done using Kaplan-Meier method. p < 0.05 by log-rank test was considered statistically significant. Statistical dat

…
Smoking among Aboriginal adults in Sydney, Australia.
Arjunan P, Poder N, Welsh K, Bellear L, Heathcote J, Wright D, Millen E, Spinks M, Williams M, Wen LM. Arjunan P, et al. Health Promot J Austr. 2016 Apr;27(1):66-69. doi: 10.1071/HE15020. Health Promot J Austr. 2016. PMID: 26235612
Inhibition of growth of Asian keloid cells with human umbilical cord Wharton's jelly stem cell-conditioned medium.
Arjunan S, Gan SU, Choolani M, Raj V, Lim J, Biswas A, Bongso A, Fong CY. Arjunan S, et al. Stem Cell Res Ther. 2020 Feb 21;11(1):78. doi: 10.1186/s13287-020-01609-7. Stem Cell Res Ther. 2020. PMID: 32085797 Free PMC article.
AKCs exposed to hWJSC-CM in vitro showed significant decreases in cell viability and proliferation, increases in Annexin V-FITC+ cell numbers, interruptions of the cell cycle at Sub-G1 and G2/M phases, altered CD marker expression, downregulated anti-apoptotic-related gene …
AKCs exposed to hWJSC-CM in vitro showed significant decreases in cell viability and proliferation, increases in Annexin V-FITC+ cell …
Dual catalytic apparatus of the thiamin diphosphate coenzyme: acid-base via the 1',4'-iminopyrimidine tautomer along with its electrophilic role.
Jordan F, Nemeria NS, Zhang S, Yan Y, Arjunan P, Furey W. Jordan F, et al. J Am Chem Soc. 2003 Oct 22;125(42):12732-8. doi: 10.1021/ja0346126. J Am Chem Soc. 2003. PMID: 14558820
The behavior of this CD band, whether it suggests saturation of the enzyme by phosphonolactylthiamin diphosphate, or its very existence (the band is not seen with the E571A E1 variant, where E571 is hydrogen bonded to the N1' atom of the 4'-aminopyrimidine ring), as well as its p …
The behavior of this CD band, whether it suggests saturation of the enzyme by phosphonolactylthiamin diphosphate, or its very existence (the …
Structural determinants of enzyme binding affinity: the E1 component of pyruvate dehydrogenase from Escherichia coli in complex with the inhibitor thiamin thiazolone diphosphate.
Arjunan P, Chandrasekhar K, Sax M, Brunskill A, Nemeria N, Jordan F, Furey W. Arjunan P, et al. Biochemistry. 2004 Mar 9;43(9):2405-11. doi: 10.1021/bi030200y. Biochemistry. 2004. PMID: 14992577
When ThTDP replaces ThDP, reorganization occurs in the protein structure in the vicinity of the active site involving positional and conformational changes in some amino acid residues, a change in the V coenzyme conformation, addition of new hydration sites, and eliminatio …
When ThTDP replaces ThDP, reorganization occurs in the protein structure in the vicinity of the active site involving positional and conform …
Superior Ionic Transferring Polymer with Silicon Dioxide Composite Membrane via Phase Inversion Method Designed for High Performance Sodium-Ion Battery.
Arjunan P, Kouthaman M, Subadevi R, Diwakar K, Liu WR, Huang CH, Sivakumar M. Arjunan P, et al. Polymers (Basel). 2020 Feb 11;12(2):405. doi: 10.3390/polym12020405. Polymers (Basel). 2020. PMID: 32053971 Free PMC article.
The material showed an initial discharge capacity of 178 mAh g(-1) at 0.1 C between 2 and 4 V with 98% columbic efficiency and 81% capacity retention after 50 cycles upon using the as-prepared PVdF-SiO(2) composite separator membrane....
The material showed an initial discharge capacity of 178 mAh g(-1) at 0.1 C between 2 and 4 V with 98% columbic efficiency and 81% ca …
Non-thermal plasma induces apoptosis in melanoma cells via production of intracellular reactive oxygen species.
Sensenig R, Kalghatgi S, Cerchar E, Fridman G, Shereshevsky A, Torabi B, Arjunan KP, Podolsky E, Fridman A, Friedman G, Azizkhan-Clifford J, Brooks AD. Sensenig R, et al. Ann Biomed Eng. 2011 Feb;39(2):674-87. doi: 10.1007/s10439-010-0197-x. Epub 2010 Oct 29. Ann Biomed Eng. 2011. Retraction in: Ann Biomed Eng. 2013 Mar;41(3):656. doi: 10.1007/s10439-013-0740-7. PMID: 21046465 Free PMC article. Retracted.
Melanoma cells were exposed to plasma at doses that did not induce necrosis, and cell viability and apoptotic activity were evaluated by Trypan blue exclusion test, Annexin-V/PI staining, caspase-3 cleavage, and TUNEL analysis. Trypan blue staining revealed that non-therma …
Melanoma cells were exposed to plasma at doses that did not induce necrosis, and cell viability and apoptotic activity were evaluated by Try …
Structure of the pyruvate dehydrogenase multienzyme complex E1 component from Escherichia coli at 1.85 A resolution.
Arjunan P, Nemeria N, Brunskill A, Chandrasekhar K, Sax M, Yan Y, Jordan F, Guest JR, Furey W. Arjunan P, et al. Biochemistry. 2002 Apr 23;41(16):5213-21. doi: 10.1021/bi0118557. Biochemistry. 2002. PMID: 11955070
The functional dimer contains two catalytic centers located at the interface between subunits. The ThDP cofactors are bound in the "V" conformation in clefts between the two subunits (binding involves the N-terminal and middle domains), and there is a common ThDP binding f …
The functional dimer contains two catalytic centers located at the interface between subunits. The ThDP cofactors are bound in the "V …
15 results