Synergistic effect of docosahexaenoic acid on anticonvulsant activity of valproic acid and lamotrigine in animal seizure models.
Gavzan H, Sayyah M, Sardari S, Babapour V.
Gavzan H, et al.
Naunyn Schmiedebergs Arch Pharmacol. 2015 Oct;388(10):1029-38. doi: 10.1007/s00210-015-1135-0. Epub 2015 May 29.
Naunyn Schmiedebergs Arch Pharmacol. 2015.
PMID: 26018398
The dose-response to DHA was obtained 15 min after intracerebroventricular (i.c.v.) injection in PTZ model of clonic seizures in mice, MES model of tonic seizures in mice, and kindling model of complex partial seizures in rats. ...
The dose-response to DHA was obtained 15 min after intracerebroventricular (i.c.v.) injection in PTZ model of clonic seizures in mice …