Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase.
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Sci Transl Med. 2016 Feb 10;8(325):325ra18. doi: 10.1126/scitranslmed.aad6833.
Sci Transl Med. 2016.
PMID: 26865566
Free PMC article.
Mechanisms underlying the associated inflammation are not fully understood, and although Langerhans cells expressing the nonclassical major histocompatibility complex (MHC) family member CD1a are known to be enriched within lesions, their role in clinical disease pathogenesis has …
Mechanisms underlying the associated inflammation are not fully understood, and although Langerhans cells expressing the nonclassical major …