A data-driven approach links microglia to pathology and prognosis in amyotrophic lateral sclerosis.
Cooper-Knock J, Green C, Altschuler G, Wei W, Bury JJ, Heath PR, Wyles M, Gelsthorpe C, Highley JR, Lorente-Pons A, Beck T, Doyle K, Otero K, Traynor B, Kirby J, Shaw PJ, Hide W.
Cooper-Knock J, et al.
Acta Neuropathol Commun. 2017 Mar 16;5(1):23. doi: 10.1186/s40478-017-0424-x.
Acta Neuropathol Commun. 2017.
PMID: 28302159
Free PMC article.
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that lacks a predictive and broadly applicable biomarker. ...Genes in the network module are important for microglial activation and predict disease progression …
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that lacks a predictive and broad …