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Inosine monophosphate dehydrogenase activity and mycophenolate pharmacokinetics in children with nephrotic syndrome treated with mycophenolate mofetil.
Sobiak J, Resztak M, Zachwieja J, Ostalska-Nowicka D. Sobiak J, et al. Among authors: resztak m. Clin Exp Pharmacol Physiol. 2022 Nov;49(11):1197-1208. doi: 10.1111/1440-1681.13706. Epub 2022 Aug 29. Clin Exp Pharmacol Physiol. 2022. PMID: 35877984
MPA clearance was the highest in younger children (median, 10.54 L/m(2) /h) and cholesterol correlated negatively with the children's age (r = -0.659, P = 0.003). ...
MPA clearance was the highest in younger children (median, 10.54 L/m(2) /h) and cholesterol correlated negatively with the children's …
Mutants at the 2-Fold Interface of Adeno-associated Virus Type 2 (AAV2) Structural Proteins Suggest a Role in Viral Transcription for AAV Capsids.
Aydemir F, Salganik M, Resztak J, Singh J, Bennett A, Agbandje-McKenna M, Muzyczka N. Aydemir F, et al. Among authors: resztak j. J Virol. 2016 Jul 27;90(16):7196-7204. doi: 10.1128/JVI.00493-16. Print 2016 Aug 15. J Virol. 2016. PMID: 27252527 Free PMC article.
We previously reported that an amino acid substitution, Y704A, near the 2-fold interface of adeno-associated virus (AAV) was defective for transcription of the packaged genome (M. Salganik, F. Aydemir, H. J. Nam, R. McKenna, M. Agbandje-McKenna, and N. ...
We previously reported that an amino acid substitution, Y704A, near the 2-fold interface of adeno-associated virus (AAV) was defective for t …
Monitoring of mycophenolate mofetil metabolites in children with nephrotic syndrome and the proposed novel target values of pharmacokinetic parameters.
Sobiak J, Resztak M, Ostalska-Nowicka D, Zachwieja J, Gąsiorowska K, Piechanowska W, Chrzanowska M. Sobiak J, et al. Among authors: resztak m. Eur J Pharm Sci. 2015 Sep 18;77:189-96. doi: 10.1016/j.ejps.2015.06.017. Epub 2015 Jun 20. Eur J Pharm Sci. 2015. PMID: 26102431
Dose-normalized MPA Ctrough and area under the concentration-time curve from 0 to 12h (AUC12) were within 0.29-6.47 mug/mL/600 mg/m(2) and 9.97-105.52 mug h/mL/600 mg/m(2), respectively. MPA Ctrough was twofold lower (p=0.024) in children with proteinuria recurrence …
Dose-normalized MPA Ctrough and area under the concentration-time curve from 0 to 12h (AUC12) were within 0.29-6.47 mug/mL/600 mg/m(2 …