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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1899 3
1902 1
1905 1
1907 2
1908 2
1909 1
1910 1
1924 1
1929 1
1930 1
1939 1
1943 1
1946 7
1947 5
1948 6
1949 2
1950 6
1951 10
1952 16
1953 9
1954 11
1955 12
1956 12
1957 19
1958 20
1959 13
1960 20
1961 21
1962 25
1963 24
1964 14
1965 17
1966 18
1967 17
1968 32
1969 23
1970 36
1971 32
1972 23
1973 43
1974 29
1975 46
1976 54
1977 55
1978 51
1979 59
1980 62
1981 61
1982 89
1983 83
1984 95
1985 105
1986 141
1987 149
1988 215
1989 188
1990 210
1991 247
1992 277
1993 260
1994 325
1995 363
1996 411
1997 398
1998 407
1999 444
2000 485
2001 596
2002 596
2003 732
2004 777
2005 846
2006 1026
2007 1062
2008 1254
2009 1415
2010 1503
2011 1757
2012 1906
2013 2223
2014 2546
2015 2945
2016 3348
2017 3469
2018 3414
2019 3767
2020 4625
2021 4803
2022 4788
2023 4775
2024 2558

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53,196 results

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Page 1
Alkaptonuria.
Mistry JB, Bukhari M, Taylor AM. Mistry JB, et al. Rare Dis. 2013 Dec 18;1:e27475. doi: 10.4161/rdis.27475. eCollection 2013. Rare Dis. 2013. PMID: 25003018 Free PMC article. Review.
Alkaptonuria (AKU) is a rare disorder of autosomal recessive inheritance. ...Over time patients develop other manifestations of AKU, due to deposition of HGA in collagenous tissues, namely ochronosis and ochronotic osteoarthropathy. Although this condition does not
Alkaptonuria (AKU) is a rare disorder of autosomal recessive inheritance. ...Over time patients develop other manifestations of AKU,
Ochronotic arthropathy in alkaptonuria.
Ali MA, Stratton R. Ali MA, et al. Rheumatology (Oxford). 2020 Nov 16:keaa660. doi: 10.1093/rheumatology/keaa660. Online ahead of print. Rheumatology (Oxford). 2020. PMID: 33197247 No abstract available.
Total knee arthroplasty in ochronosis.
Patel VG. Patel VG. Arthroplast Today. 2015 Aug 28;1(3):77-80. doi: 10.1016/j.artd.2015.03.003. eCollection 2015 Sep. Arthroplast Today. 2015. PMID: 28326376 Free PMC article.
Alkaptonuria is disorder of tyrosine metabolism due to deficiency of homogentisic oxidase characterized by excretion of homogentisic acid in urine, deposition of oxidized homogensitate pigments in connective tissues and articular cartilages (ochronosis). ...Manageme
Alkaptonuria is disorder of tyrosine metabolism due to deficiency of homogentisic oxidase characterized by excretion of homogentisic
Total Hip Arthroplasty for Ochronosis: A Report of Three Cases.
Arasu JAD, Prasanna AA. Arasu JAD, et al. J Orthop Case Rep. 2022 Nov;12(11):23-27. doi: 10.13107/jocr.2022.v12.i11.3400. J Orthop Case Rep. 2022. PMID: 37013237 Free PMC article.
INTRODUCTION: Ochronosis is a rare metabolic disorder, characterized by accumulation of homogentisic acid in the connective tissues due to the lack of the enzyme homogentisic acid oxidase. The musculoskeletal manifestation of alkaptonuria is black pigmentation of ca …
INTRODUCTION: Ochronosis is a rare metabolic disorder, characterized by accumulation of homogentisic acid in the connective tissues d …
Total Knee Replacement in Alkaptonuric Ochronosis.
Pesciallo C, Garabano G, Rodriguez J, Viale G, Tillet F, Del Sel H. Pesciallo C, et al. Acta Biomed. 2022 Jun 7;93(S1):e2022108. doi: 10.23750/abm.v92iS1.10439. Acta Biomed. 2022. PMID: 35671127 Free PMC article.
BACKGROUND AND OBJECTIVE: Alkaptonuria is a rare disease characterized by the accumulation of homogentisic acid (HGA). Over time, these patients may develop disabling ochronotic arthropathy. We present 2 cases of patients with end-stage arthropathy treated wi …
BACKGROUND AND OBJECTIVE: Alkaptonuria is a rare disease characterized by the accumulation of homogentisic acid (HGA). Over time, the …
Total knee prosthesis in a patient diagnosed with ochronotic arthropathy.
Sabater M, Alías A, Segur JM. Sabater M, et al. Rev Esp Cir Ortop Traumatol (Engl Ed). 2021 Jan-Feb;65(1):69-72. doi: 10.1016/j.recot.2020.01.005. Epub 2020 Mar 17. Rev Esp Cir Ortop Traumatol (Engl Ed). 2021. PMID: 32192929 Free article. English, Spanish.
In the joints, it can lead to early and very disabling arthropathy, known as ochronotic arthropathy. We present the case of a patient diagnosed with ochronosis and ochronotic arthropathy of the left knee, in which we describe the intraoperative …
In the joints, it can lead to early and very disabling arthropathy, known as ochronotic arthropathy. We present the case of a …
Total Knee Arthroplasty in Ochronosis: A Rare Condition.
Arora A, Asnake G, Pandav K. Arora A, et al. Cureus. 2023 Jan 8;15(1):e33523. doi: 10.7759/cureus.33523. eCollection 2023 Jan. Cureus. 2023. PMID: 36779093 Free PMC article.
Ochronosis is a rare metabolic disorder characterized by homogentisic acid deposition in the large joints and spine, resulting in progressive degeneration. We present two cases of ochronotic arthritis of the knee subjected to cemented total knee arthroplas
Ochronosis is a rare metabolic disorder characterized by homogentisic acid deposition in the large joints and spine, resulting in pro
Ochronosis as Etiology of Requiring Total Knee Arthroplasty-A Case Series.
Pierce TP, Issa K, Ramirez A, Sclafani S, Harwin SF, Scillia AJ, Rifai A, McInerney VK. Pierce TP, et al. Surg Technol Int. 2016 Oct 26;29:261-264. Surg Technol Int. 2016. PMID: 27466876
Therefore, we are reporting a multicenter case series of three patients (four arthroplasties) who presented with signs and symptoms of ochronotic arthropathy-and eventually underwent total knee arthroplasty (TKA)-and provide a review of the curr …
Therefore, we are reporting a multicenter case series of three patients (four arthroplasties) who presented with signs and symptoms of oc
Ochronosis.
Di Matteo B, Marcacci M. Di Matteo B, et al. N Engl J Med. 2021 Feb 4;384(5):461. doi: 10.1056/NEJMicm2025932. Epub 2021 Jan 30. N Engl J Med. 2021. PMID: 33535288 No abstract available.
Alkaptonuria.
Thapa M, Bhatia M, Maurya VK. Thapa M, et al. Med J Armed Forces India. 2018 Oct;74(4):394-396. doi: 10.1016/j.mjafi.2017.06.006. Epub 2017 Jul 25. Med J Armed Forces India. 2018. PMID: 30449931 Free PMC article. No abstract available.
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