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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1933 1
1948 1
1956 1
1962 1
1963 1
1964 2
1967 1
1968 1
1969 1
1970 1
1972 1
1973 1
1974 1
1975 8
1976 3
1977 7
1978 3
1979 8
1980 16
1981 12
1982 10
1983 10
1984 30
1985 20
1986 30
1987 40
1988 35
1989 38
1990 55
1991 58
1992 48
1993 62
1994 61
1995 104
1996 83
1997 106
1998 121
1999 162
2000 189
2001 222
2002 277
2003 284
2004 365
2005 465
2006 598
2007 727
2008 712
2009 818
2010 949
2011 1102
2012 1140
2013 1260
2014 1375
2015 1460
2016 1457
2017 1498
2018 1663
2019 1778
2020 2109
2021 2375
2022 2587
2023 2386
2024 1288

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26,613 results

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Page 1
Regulation of Proliferation, Differentiation and Functions of Osteoblasts by Runx2.
Komori T. Komori T. Int J Mol Sci. 2019 Apr 4;20(7):1694. doi: 10.3390/ijms20071694. Int J Mol Sci. 2019. PMID: 30987410 Free PMC article. Review.
Runx2 enhances the proliferation of suture mesenchymal cells and induces their commitment into osteoblast lineage cells through the direct regulation of hedgehog (Ihh, Gli1, and Ptch1), Fgf (Fgfr2 and Fgfr3), Wnt (Tcf7, Wnt10b, and Wnt1), and Pthlh (Pthr1) signaling pathwa …
Runx2 enhances the proliferation of suture mesenchymal cells and induces their commitment into osteoblast lineage cells through the direct r …
Genetic regulatory pathways of split-hand/foot malformation.
Kantaputra PN, Carlson BM. Kantaputra PN, et al. Clin Genet. 2019 Jan;95(1):132-139. doi: 10.1111/cge.13434. Epub 2018 Sep 10. Clin Genet. 2019. PMID: 30101460 Free article. Review.
Split-hand/foot malformation (SHFM) is caused by mutations in TP63, DLX5, DLX6, FGF8, FGFR1, WNT10B, and BHLHA9. The clinical features of SHFM caused by mutations of these genes are not distinguishable. ...
Split-hand/foot malformation (SHFM) is caused by mutations in TP63, DLX5, DLX6, FGF8, FGFR1, WNT10B, and BHLHA9. The cl …
DLX6-AS1: A Long Non-coding RNA With Oncogenic Features.
Ghafouri-Fard S, Najafi S, Hussen BM, Ganjo AR, Taheri M, Samadian M. Ghafouri-Fard S, et al. Front Cell Dev Biol. 2022 Feb 25;10:746443. doi: 10.3389/fcell.2022.746443. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35281110 Free PMC article. Review.
These pathways form axes through which DLX6-AS1 promotes carcinogenicity of cancer cells. Xenograft animal studies, also have confirmed enhancing effect of DLX6-AS1 on tumor growth and metastasis. ...Survival analyses have demonstrated correlation between high DL
These pathways form axes through which DLX6-AS1 promotes carcinogenicity of cancer cells. Xenograft animal studies, also have confirm …
The role of WNT10B in physiology and disease: A 10-year update.
Perkins RS, Singh R, Abell AN, Krum SA, Miranda-Carboni GA. Perkins RS, et al. Front Cell Dev Biol. 2023 Feb 6;11:1120365. doi: 10.3389/fcell.2023.1120365. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 36814601 Free PMC article. Review.
We reviewed WNT10B a decade ago, and here we provide a comprehensive update to the field. ...We also discussed the therapeutic implications of WNT10B regulation. In summary, research conducted during 2012-2022 revealed several new, diverse functions in the role of …
We reviewed WNT10B a decade ago, and here we provide a comprehensive update to the field. ...We also discussed the therapeutic implic …
Strategies of LncRNA DLX6-AS1 on Study and Therapeutics.
Zhao Y, Li P. Zhao Y, et al. Front Genet. 2022 Jun 1;13:871988. doi: 10.3389/fgene.2022.871988. eCollection 2022. Front Genet. 2022. PMID: 35719380 Free PMC article. Review.
In addition, the presence of lncRNA DLX6-AS1 in the exosomes of peripheral blood of patients with tumors may also contribute to it being a possible cancer-related biomarker. ...This review aims to summarize the research statuses of lncRNA DLX6-AS1, discuss other stu …
In addition, the presence of lncRNA DLX6-AS1 in the exosomes of peripheral blood of patients with tumors may also contribute to it be …
DLX6-AS1: An Indispensable Cancer-related Long Non-coding RNA.
Hu C, Liu K, Wang B, Xu W, Lin Y, Yuan C. Hu C, et al. Curr Pharm Des. 2021;27(9):1211-1218. doi: 10.2174/1381612826666201029100151. Curr Pharm Des. 2021. PMID: 33121401 Review.
This review aims to probe into the pathophysiological functions and molecular mechanisms of DLX6-AS1 in various cancers. METHODS: By retrieving the literature, this review summarizes the biological function and mechanism of LncRNA DLX6-AS1 in tumor occurrence. ...CO …
This review aims to probe into the pathophysiological functions and molecular mechanisms of DLX6-AS1 in various cancers. METHODS: By …
Split Hand-Foot and Deafness in a Patient with 7q21.13-q21.3 Deletion Not Including the DLX5/6 Genes.
Ambrosetti I, Bernardini L, Pollazzon M, Giuffrida MG, Guida V, Peluso F, Baroni MC, Polizzi V, Napoli M, Rosato S, Trimarchi G, Gelmini C, Caraffi SG, Wischmeijer A, Frattini D, Novelli A, Garavelli L. Ambrosetti I, et al. Genes (Basel). 2023 Jul 26;14(8):1526. doi: 10.3390/genes14081526. Genes (Basel). 2023. PMID: 37628577 Free PMC article. Review.
Associated features often include hearing loss, intellectual disability/developmental delay and craniofacial abnormalities. Disruption of the DLX5/DLX6 genes, mapping within the SHFM1 locus, is now known to be responsible for the phenotype. ...We further demonstrate …
Associated features often include hearing loss, intellectual disability/developmental delay and craniofacial abnormalities. Disruption of th …
DLX6-AS1 is a potential biomarker and therapeutic target in cancer initiation and progression.
Zheng Q, Gu X, Yang Q, Chu Q, Dai Y, Chen Z. Zheng Q, et al. Clin Chim Acta. 2021 Jun;517:1-8. doi: 10.1016/j.cca.2021.02.006. Epub 2021 Feb 17. Clin Chim Acta. 2021. PMID: 33607068 Review.
They play prominent roles in the pathogenesis of human cancer, and contribute to every hallmark of cancer. The novel cancer-related lncRNA DLX6 antisense RNA 1 (DLX6-AS1) plays an essential regulatory role in enhancing and initiating carcinogenesis and tumor progres …
They play prominent roles in the pathogenesis of human cancer, and contribute to every hallmark of cancer. The novel cancer-related lncRNA …
Promising long noncoding RNA DLX6-AS1 in malignant tumors.
Xue C, Lv L, Jiang J, Li L. Xue C, et al. Am J Transl Res. 2020 Dec 15;12(12):7682-7692. eCollection 2020. Am J Transl Res. 2020. PMID: 33437353 Free PMC article. Review.
Importantly, DLX6-AS1 is closely associated with tumor cell proliferation, apoptosis, invasion, and migration. Patients with high DLX6-AS1 expression often had poorer prognosis than those with low expression. ...
Importantly, DLX6-AS1 is closely associated with tumor cell proliferation, apoptosis, invasion, and migration. Patients with high …
DLX5 promotes Col10a1 expression and chondrocyte hypertrophy and is involved in osteoarthritis progression.
Chen J, Chen F, Wu X, Bian H, Chen C, Zhang X, Hei R, XiaotongYang, Yuan H, Wang Q, Lu Y, Qiao L, Zheng Q. Chen J, et al. Genes Dis. 2023 Feb 1;10(5):2097-2108. doi: 10.1016/j.gendis.2022.12.016. eCollection 2023 Sep. Genes Dis. 2023. PMID: 37492739 Free PMC article.
Forced expression of Dlx5 further increases, while knockdown of Dlx5 decreases COL10A1 expression in hypertrophic MCT cells. ...Notably, forced overexpression of DLX5 in hypertrophic MCT cells up-regulates RUNX2, and adjacent DLX5 and RUNX2 binding sit …
Forced expression of Dlx5 further increases, while knockdown of Dlx5 decreases COL10A1 expression in hypertrophic MCT cells. . …
26,613 results
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