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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1980 1
1981 3
1982 4
1983 1
1984 1
1985 4
1987 2
1988 6
1989 3
1990 2
1991 3
1992 3
1993 5
1994 2
1995 4
1996 9
1997 4
1998 5
1999 10
2000 4
2001 8
2002 9
2003 13
2004 11
2005 16
2006 14
2007 13
2008 9
2009 12
2010 3
2011 7
2012 5
2013 4
2014 4
2015 1
2016 6
2017 2
2018 3
2019 4
2020 3
2021 1
2022 3
2023 4
2024 2

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227 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Interactions Between Antenatal Sulfadoxine-Pyrimethamine, Drug-Resistant Plasmodium falciparum Parasites, and Delivery Outcomes in Malawi.
Taylor SM, Levitt B, Freedman B, Madanitsa M, Thwai KL, Kalilani-Phiri L, Khairallah C, Mwapasa V, Ter Kuile FO, Meshnick SR. Taylor SM, et al. J Infect Dis. 2020 Jul 23;222(4):661-669. doi: 10.1093/infdis/jiaa145. J Infect Dis. 2020. PMID: 32221555 Free PMC article. Clinical Trial.
BACKGROUND: Sulfadoxine-pyrimethamine (SP) is used as intermittent preventive therapy in pregnancy (IPTp) for malaria in sub-Saharan Africa. The resistance marker dhps A581G has been associated with reduced IPTp-SP efficacy and enhanced morbidity in SP recipients. . …
BACKGROUND: Sulfadoxine-pyrimethamine (SP) is used as intermittent preventive therapy in pregnancy (IPTp) for malaria in sub-Saharan …
Low-dose treatment with sulfadoxine-pyrimethamine combinations selects for drug-resistant Plasmodium falciparum strains.
Kun JF, Lehman LG, Lell B, Schmidt-Ott R, Kremsner PG. Kun JF, et al. Antimicrob Agents Chemother. 1999 Sep;43(9):2205-8. doi: 10.1128/AAC.43.9.2205. Antimicrob Agents Chemother. 1999. PMID: 10471565 Free PMC article. Clinical Trial.
A total of 252 children were enrolled in a drug trial to assess the effect of minimal doses of sulfadoxine (Sdx) and pyrimethamine (Pyr). Parasite samples isolated from these patients were analyzed before and after treatment to investigate the level of drug-resistant …
A total of 252 children were enrolled in a drug trial to assess the effect of minimal doses of sulfadoxine (Sdx) and pyrimethamine (P …
Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.
Crider K, Williams J, Qi YP, Gutman J, Yeung L, Mai C, Finkelstain J, Mehta S, Pons-Duran C, Menéndez C, Moraleda C, Rogers L, Daniels K, Green P. Crider K, et al. Cochrane Database Syst Rev. 2022 Feb 1;2(2022):CD014217. doi: 10.1002/14651858.CD014217. Cochrane Database Syst Rev. 2022. PMID: 36321557 Free PMC article.
Due to increasing resistance to SP, in 2000 the WHO recommended that one of several artemisinin-based combination therapies (ACTs) be used instead of SP for the treatment of uncomplicated malaria caused by Plasmodium falciparum (Global Partnership to Roll Back Malar …
Due to increasing resistance to SP, in 2000 the WHO recommended that one of several artemisinin-based combination therapies (ACTs) be …
Effect of Plasmodium falciparum sulfadoxine-pyrimethamine resistance on the effectiveness of intermittent preventive therapy for malaria in pregnancy in Africa: a systematic review and meta-analysis.
van Eijk AM, Larsen DA, Kayentao K, Koshy G, Slaughter DEC, Roper C, Okell LC, Desai M, Gutman J, Khairallah C, Rogerson SJ, Hopkins Sibley C, Meshnick SR, Taylor SM, Ter Kuile FO. van Eijk AM, et al. Lancet Infect Dis. 2019 May;19(5):546-556. doi: 10.1016/S1473-3099(18)30732-1. Epub 2019 Mar 25. Lancet Infect Dis. 2019. PMID: 30922818 Free article.
BACKGROUND: Resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine threatens the antimalarial effectiveness of intermittent preventive treatment during pregnancy (IPTp) in sub-Saharan Africa. We aimed to assess the associations between markers of …
BACKGROUND: Resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine threatens the antimalarial effectiveness o …
Effect of monthly intermittent preventive treatment with dihydroartemisinin-piperaquine with and without azithromycin versus monthly sulfadoxine-pyrimethamine on adverse pregnancy outcomes in Africa: a double-blind randomised, partly placebo-controlled trial.
Madanitsa M, Barsosio HC, Minja DTR, Mtove G, Kavishe RA, Dodd J, Saidi Q, Onyango ED, Otieno K, Wang D, Ashorn U, Hill J, Mukerebe C, Gesase S, Msemo OA, Mwapasa V, Phiri KS, Maleta K, Klein N, Magnussen P, Lusingu JPA, Kariuki S, Mosha JF, Alifrangis M, Hansson H, Schmiegelow C, Gutman JR, Chico RM, Ter Kuile FO. Madanitsa M, et al. Lancet. 2023 Mar 25;401(10381):1020-1036. doi: 10.1016/S0140-6736(22)02535-1. Epub 2023 Mar 10. Lancet. 2023. PMID: 36913959 Free PMC article. Clinical Trial.
BACKGROUND: Intermittent preventive treatment in pregnancy (IPTp) with dihydroartemisinin-piperaquine is more effective than IPTp with sulfadoxine-pyrimethamine at reducing malaria infection during pregnancy in areas with high-grade resistance to sulfadoxine- …
BACKGROUND: Intermittent preventive treatment in pregnancy (IPTp) with dihydroartemisinin-piperaquine is more effective than IPTp with su …
Risk of drug resistance in Plasmodium falciparum malaria therapy-a systematic review and meta-analysis.
Zhou LJ, Xia J, Wei HX, Liu XJ, Peng HJ. Zhou LJ, et al. Parasitol Res. 2017 Feb;116(2):781-788. doi: 10.1007/s00436-016-5353-2. Epub 2016 Dec 27. Parasitol Res. 2017. PMID: 28028628 Review.
Plasmodium falciparum is responsible for the vast majority of the morbidity and mortality associated with malaria infection globally. Although a number of studies have reported the emergence of drug resistance in different therapies for P. falciparum infection, the …
Plasmodium falciparum is responsible for the vast majority of the morbidity and mortality associated with malaria infection globally. …
[Comparative study of sulfadoxine-pyrimethamine and amodiaquine + sulfadoxine-pyrimethamine for the treatment of malaria caused by chloroquine-resistant Plasmodium falciparum in Maputo, Mozambique].
Dinis DV, Schapira A. Dinis DV, et al. Bull Soc Pathol Exot. 1990;83(4):521-7; discussion 528. Bull Soc Pathol Exot. 1990. PMID: 2286005 Clinical Trial. French.
The two treatments were sulfadoxine 25 mg/kg + pyrimethamine 1.25 mg/kg as a single dose (S + P) and amodiaquine 10 + 10 + 5 mg/kg over three days with sulfadoxine + pyrimethamine on the third day (A + S + P). ...The probably slightly higher cure rate with the tripl …
The two treatments were sulfadoxine 25 mg/kg + pyrimethamine 1.25 mg/kg as a single dose (S + P) and amodiaquine 10 + 10 + 5 mg/kg ov …
Prevalence of and risk factors for microscopic and submicroscopic malaria infections in pregnancy: a systematic review and meta-analysis.
van Eijk AM, Stepniewska K, Hill J, Taylor SM, Rogerson SJ, Cottrell G, Chico RM, Gutman JR, Tinto H, Unger HW, Yanow SK, Meshnick SR, Ter Kuile FO, Mayor A; Subpatent Malaria in Pregnancy Group. van Eijk AM, et al. Lancet Glob Health. 2023 Jul;11(7):e1061-e1074. doi: 10.1016/S2214-109X(23)00194-8. Epub 2023 Jun 2. Lancet Glob Health. 2023. PMID: 37276878 Free article.
We obtained IPD (when available) and aggregated data. Estimates of malaria transmission intensity and sulfadoxine-pyrimethamine resistance, matched by study location and year, were obtained using publicly available data. ...Among women with NAAT-positive infections …
We obtained IPD (when available) and aggregated data. Estimates of malaria transmission intensity and sulfadoxine-pyrimethamine re …
Clinical trials of artesunate plus sulfadoxine-pyrimethamine for Plasmodium falciparum malaria in Afghanistan: maintained efficacy a decade after introduction.
Awab GR, Imwong M, Pukrittayakamee S, Alim F, Hanpithakpong W, Tarning J, Dondorp AM, Day NP, White NJ, Woodrow CJ. Awab GR, et al. Malar J. 2016 Feb 25;15:121. doi: 10.1186/s12936-016-1167-z. Malar J. 2016. PMID: 26917051 Free PMC article. Clinical Trial.
BACKGROUND: Combination therapy with artesunate plus sulfadoxine-pyrimethamine (SP) was adopted as recommended treatment for Plasmodium falciparum infection in Afghanistan in 2003. ...The molecular data indicate that despite a substantial fall in incidence, resis …
BACKGROUND: Combination therapy with artesunate plus sulfadoxine-pyrimethamine (SP) was adopted as recommended treatment for Plasm …
Anti-malarial treatment outcomes in Ethiopia: a systematic review and meta-analysis.
Gebreyohannes EA, Bhagavathula AS, Seid MA, Tegegn HG. Gebreyohannes EA, et al. Malar J. 2017 Jul 3;16(1):269. doi: 10.1186/s12936-017-1922-9. Malar J. 2017. PMID: 28673348 Free PMC article. Review.

However, treatment success was higher in falciparum malaria patients treated with artemether-lumefantrine than chloroquine for Plasmodium vivax patients [98.1% (97.0-99.2), p < 0.001, I (2) = 72.55 vs 94.7% (92.6-96.2), p < 0.001, I (2) = 53.62%]. ...The results of t

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However, treatment success was higher in falciparum malaria patients treated with artemether-lumefantrine than chloroquine for Plasmodium …
227 results