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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 2
1972 1
1974 2
1975 7
1976 5
1977 4
1978 3
1979 9
1980 9
1981 10
1982 8
1983 11
1984 18
1985 23
1986 24
1987 41
1988 38
1989 45
1990 58
1991 72
1992 85
1993 80
1994 71
1995 105
1996 110
1997 98
1998 83
1999 104
2000 87
2001 90
2002 107
2003 104
2004 99
2005 131
2006 135
2007 118
2008 117
2009 130
2010 127
2011 162
2012 174
2013 182
2014 190
2015 149
2016 166
2017 191
2018 180
2019 141
2020 179
2021 158
2022 203
2023 170
2024 51

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Search Results

4,239 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Balanced Multielectrolyte Solution versus Saline in Critically Ill Adults.
Finfer S, Micallef S, Hammond N, Navarra L, Bellomo R, Billot L, Delaney A, Gallagher M, Gattas D, Li Q, Mackle D, Mysore J, Saxena M, Taylor C, Young P, Myburgh J; PLUS Study Investigators and the Australian New Zealand Intensive Care Society Clinical Trials Group. Finfer S, et al. N Engl J Med. 2022 Mar 3;386(9):815-826. doi: 10.1056/NEJMoa2114464. Epub 2022 Jan 18. N Engl J Med. 2022. PMID: 35041780 Clinical Trial.
BACKGROUND: Whether the use of balanced multielectrolyte solution (BMES) in preference to 0.9% sodium chloride solution (saline) in critically ill patients reduces the risk of acute kidney injury or death is uncertain. METHODS: In a double-blind …
BACKGROUND: Whether the use of balanced multielectrolyte solution (BMES) in preference to 0.9% sodium chloride solut …
Sodium chloride or Plasmalyte-148 evaluation in severe diabetic ketoacidosis (SCOPE-DKA): a cluster, crossover, randomized, controlled trial.
Ramanan M, Attokaran A, Murray L, Bhadange N, Stewart D, Rajendran G, Pusapati R, Petty M, Garrett P, Kruger P, Peake S, Billot L, Venkatesh B; SCOPE-DKA Collaborators and Queensland Critical Care Research Network (QCCRN). Ramanan M, et al. Intensive Care Med. 2021 Nov;47(11):1248-1257. doi: 10.1007/s00134-021-06480-5. Epub 2021 Oct 5. Intensive Care Med. 2021. PMID: 34609547 Clinical Trial.
PURPOSE: To determine whether treatment with Plasmalyte-148 (PL) compared to sodium chloride 0.9% (SC) results in faster resolution of diabetic ketoacidosis (DKA) and whether the acetate in PL potentiates ketosis. ...The median ICU and hospital lengths of stay were …
PURPOSE: To determine whether treatment with Plasmalyte-148 (PL) compared to sodium chloride 0.9% (SC) results in faster resol …
Heparin versus 0.9% sodium chloride locking for prevention of occlusion in central venous catheters in adults.
López-Briz E, Ruiz Garcia V, Cabello JB, Bort-Martí S, Carbonell Sanchis R. López-Briz E, et al. Cochrane Database Syst Rev. 2022 Jul 18;7(7):CD008462. doi: 10.1002/14651858.CD008462.pub4. Cochrane Database Syst Rev. 2022. PMID: 35849083 Free PMC article. Review.
There are systematic variations in care: some practitioners use heparin (at different concentrations), whilst others use 0.9% sodium chloride (normal saline). This review looks at the effectiveness and safety of intermittent locking with heparin compared to n …
There are systematic variations in care: some practitioners use heparin (at different concentrations), whilst others use 0.9% sodium …
Is Epidural Injection of Sodium Chloride Solution a True Placebo or an Active Control Agent? A Systematic Review and Meta-Analysis.
Manchikanti L, Knezevic NN, Sanapati J, Kaye AD, Sanapati MR, Hirsch JA. Manchikanti L, et al. Pain Physician. 2021 Jan;24(1):41-59. Pain Physician. 2021. PMID: 33400427 Free article.
STUDY DESIGN: A systematic review of randomized controlled trials utilizing sodium chloride solution alone, steroids alone, or sodium chloride solution with steroids in managing spinal pain secondary to disc herniation or spinal stenosis. …
STUDY DESIGN: A systematic review of randomized controlled trials utilizing sodium chloride solution alone, steroids al …
Multiple Electrolytes Solution Versus Saline as Bolus Fluid for Resuscitation in Pediatric Septic Shock: A Multicenter Randomized Clinical Trial.
Sankar J, Muralidharan J, Lalitha AV, Rameshkumar R, Pathak M, Das RR, Nadkarni VM, Ismail J, Subramanian M, Nallasamy K, Dev N, Kumar UV, Kumar K, Sharma T, Jaravta K, Thakur N, Aggarwal P, Jat KR, Kabra SK, Lodha R. Sankar J, et al. Crit Care Med. 2023 Nov 1;51(11):1449-1460. doi: 10.1097/CCM.0000000000005952. Epub 2023 Jun 9. Crit Care Med. 2023. PMID: 37294145 Clinical Trial.
OBJECTIVE: To determine if initial fluid resuscitation with balanced crystalloid (e.g., multiple electrolytes solution [MES]) or 0.9% saline adversely affects kidney function in children with septic shock. ...Key secondary outcomes included hyperchloremia, any adver …
OBJECTIVE: To determine if initial fluid resuscitation with balanced crystalloid (e.g., multiple electrolytes solution [MES]) or 0.9% …
Balanced crystalloid solutions versus 0.9% saline for treating acute diarrhoea and severe dehydration in children.
Florez ID, Sierra J, Pérez-Gaxiola G. Florez ID, et al. Cochrane Database Syst Rev. 2023 May 17;5(5):CD013640. doi: 10.1002/14651858.CD013640.pub2. Cochrane Database Syst Rev. 2023. PMID: 37196992 Free PMC article.
SELECTION CRITERIA: We included randomized controlled trials in children with severe dehydration due to acute diarrhoea comparing balanced solutions, such as Ringer's lactate or Plasma-Lyte with 0.9% saline solution, for rapid rehydration. DATA COLLECTION AND ANALYS …
SELECTION CRITERIA: We included randomized controlled trials in children with severe dehydration due to acute diarrhoea comparing balanced s …
Effect of Saline vs Gluconate/Acetate-Buffered Solution vs Lactate-Buffered Solution on Serum Chloride Among Children in the Pediatric Intensive Care Unit: The SPLYT-P Randomized Clinical Trial.
Raman S, Gibbons KS, Mattke A, Schibler A, Trnka P, Kennedy M, Le Marsney R, Schlapbach LJ. Raman S, et al. JAMA Pediatr. 2023 Feb 1;177(2):122-131. doi: 10.1001/jamapediatrics.2022.4912. JAMA Pediatr. 2023. PMID: 36534387 Free PMC article. Clinical Trial.
RESULTS: A total of 516 patients with a median (IQR) age of 3.8 (1.0-10.4) years were randomized with 178, 171, and 167 allocated to gluconate/acetate-buffered solution, lactate-buffered solution, and saline, respectively. The serum chloride level incr …
RESULTS: A total of 516 patients with a median (IQR) age of 3.8 (1.0-10.4) years were randomized with 178, 171, and 167 allocated to glucona …
Pivotal Phase 3 Randomized Clinical Trial of the Safety, Tolerability, and Immunogenicity of 20-Valent Pneumococcal Conjugate Vaccine in Adults Aged ≥18 Years.
Essink B, Sabharwal C, Cannon K, Frenck R, Lal H, Xu X, Sundaraiyer V, Peng Y, Moyer L, Pride MW, Scully IL, Jansen KU, Gruber WC, Scott DA, Watson W. Essink B, et al. Clin Infect Dis. 2022 Aug 31;75(3):390-398. doi: 10.1093/cid/ciab990. Clin Infect Dis. 2022. PMID: 34940806 Free PMC article. Clinical Trial.
After 1 month, participants aged 60 years also received 1 dose of saline or 23-valent polysaccharide vaccine (PPSV23). Safety assessments included local reactions, systemic events, adverse events, serious adverse events, and newly diagnosed chronic medical conditions. Opso …
After 1 month, participants aged 60 years also received 1 dose of saline or 23-valent polysaccharide vaccine (PPSV23). Safety assessm …
Effectiveness of Intranasal Mometasone Furoate vs Saline for Sleep-Disordered Breathing in Children: A Randomized Clinical Trial.
Baker A, Grobler A, Davies K, Griffiths A, Hiscock H, Kubba H, Peters RL, Ranganathan S, Rimmer J, Rose E, Rowe K, Simpson CM, Davidson A, Nixon G, Perrett KP. Baker A, et al. JAMA Pediatr. 2023 Mar 1;177(3):240-247. doi: 10.1001/jamapediatrics.2022.5258. JAMA Pediatr. 2023. PMID: 36648937 Free PMC article. Clinical Trial.
INTERVENTIONS: Participants were randomly assigned to receive mometasone furoate, 50 mug, or sodium chloride (saline), 0.9%, 1 spray per nostril daily, dispensed in identical bottles. ...The main adverse effects were epistaxis, affecting 12 of 124 participant …
INTERVENTIONS: Participants were randomly assigned to receive mometasone furoate, 50 mug, or sodium chloride (saline), …
Wound cleansing for treating venous leg ulcers.
McLain NE, Moore ZE, Avsar P. McLain NE, et al. Cochrane Database Syst Rev. 2021 Mar 10;3(3):CD011675. doi: 10.1002/14651858.CD011675.pub2. Cochrane Database Syst Rev. 2021. PMID: 33734426 Free PMC article.
In one study comparing propyl betaine and polihexanide with saline solution the authors do not report any adverse events occurring. ...From the four studies identified, there is insufficient evidence to demonstrate whether the use of PHMB solution compared wi …
In one study comparing propyl betaine and polihexanide with saline solution the authors do not report any adverse events occur …
4,239 results