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Effect of heart rate control with esmolol on hemodynamic and clinical outcomes in patients with septic shock: a randomized clinical trial.
Morelli A, Ertmer C, Westphal M, Rehberg S, Kampmeier T, Ligges S, Orecchioni A, D'Egidio A, D'Ippoliti F, Raffone C, Venditti M, Guarracino F, Girardis M, Tritapepe L, Pietropaoli P, Mebazaa A, Singer M. Morelli A, et al. JAMA. 2013 Oct 23;310(16):1683-91. doi: 10.1001/jama.2013.278477. JAMA. 2013. PMID: 24108526 Clinical Trial.
MAIN OUTCOMES AND MEASURES: Our primary outcome was a reduction in heart rate below the predefined threshold of 95/min and to maintain heart rate between 80/min and 94/min by esmolol treatment over a 96-hour period. ...RESULTS: Targeted heart rates were achie …
MAIN OUTCOMES AND MEASURES: Our primary outcome was a reduction in heart rate below the predefined threshold of 95/min and to maintai …
Cardiac Function Before Sepsis and Clinical Outcomes.
Iyer S, Kennedy JN, Jentzer JC, Senussi MH, Seymour CW. Iyer S, et al. JAMA. 2024 May 7;331(17):1496-1499. doi: 10.1001/jama.2024.3917. JAMA. 2024. PMID: 38587828
This cohort study characterizes heterogeneity in cardiac function prior to sepsis and describes associations with hospitalization outcomes and mortality....
This cohort study characterizes heterogeneity in cardiac function prior to sepsis and describes associations with hospi …