Genome-wide multi-trait analysis of irritable bowel syndrome and related mental conditions identifies 38 new independent variants.
Alemany S, Soler-Artigas M, Cabana-Domínguez J, Fakhreddine D, Llonga N, Vilar-Ribó L, Rodríguez-Urrutia A, Palacio J, González-Castro AM, Lobo B, Alonso-Cotoner C, Simrén M, Santos J, Ramos-Quiroga JA, Ribasés M.
Alemany S, et al.
J Transl Med. 2023 Apr 21;21(1):272. doi: 10.1186/s12967-023-04107-5.
J Transl Med. 2023.
PMID: 37085903
Free PMC article.
METHODS: We quantified the genetic overlap between IBS, neuroticism, depression and anxiety, conducted a multi-trait genome-wide association study (GWAS) considering these traits and investigated causal relationships between them by using the largest GWAS to date. ...
METHODS: We quantified the genetic overlap between IBS, neuroticism, depression and anxiety, conducted a multi-trait genome-wide association …