Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1974 2
1975 1
1976 2
1977 3
1978 3
1980 1
1981 6
1982 4
1984 2
1985 2
1986 2
1987 4
1988 1
1989 9
1990 4
1991 2
1992 3
1993 5
1994 6
1995 2
1996 7
1997 2
1998 6
1999 3
2000 8
2001 3
2003 2
2004 2
2005 7
2006 3
2007 2
2008 3
2009 1
2010 1
2011 4
2012 1
2013 3
2014 5
2015 5
2016 2
2017 1
2018 2
2019 1
2020 8
2021 3
2022 3
2023 3
2024 2

Text availability

Article attribute

Article type

Publication date

Search Results

154 results

Results by year

Citations

1 article found by citation matching

Search results

Filters applied: . Clear all
Page 1
Circadian control of brain glymphatic and lymphatic fluid flow.
Hablitz LM, Plá V, Giannetto M, Vinitsky HS, Stæger FF, Metcalfe T, Nguyen R, Benrais A, Nedergaard M. Hablitz LM, et al. Nat Commun. 2020 Sep 2;11(1):4411. doi: 10.1038/s41467-020-18115-2. Nat Commun. 2020. PMID: 32879313 Free PMC article.
The glymphatic system is a network of perivascular spaces that promotes movement of cerebrospinal fluid (CSF) into the brain and clearance of metabolic waste. This fluid transport system is supported by the water channel aquaporin-4 (AQP4) localized to vascular endfeet of …
The glymphatic system is a network of perivascular spaces that promotes movement of cerebrospinal fluid (CSF) into the brain and clea …
The Glymphatic System: A Novel Component of Fundamental Neurobiology.
Hablitz LM, Nedergaard M. Hablitz LM, et al. J Neurosci. 2021 Sep 15;41(37):7698-7711. doi: 10.1523/JNEUROSCI.0619-21.2021. J Neurosci. 2021. PMID: 34526407 Free PMC article. Review.
This review focuses on important questions about the structure of this system, why the brain needs a fluid transport system, and unexplored aspects of brain fluid transport. ...Much remains to be studied, but we propose that the glymphatic/lymphatic system acts as a …
This review focuses on important questions about the structure of this system, why the brain needs a fluid transport system, and unex …
Aquaporin-4-dependent glymphatic solute transport in the rodent brain.
Mestre H, Hablitz LM, Xavier AL, Feng W, Zou W, Pu T, Monai H, Murlidharan G, Castellanos Rivera RM, Simon MJ, Pike MM, Plá V, Du T, Kress BT, Wang X, Plog BA, Thrane AS, Lundgaard I, Abe Y, Yasui M, Thomas JH, Xiao M, Hirase H, Asokan A, Iliff JJ, Nedergaard M. Mestre H, et al. Elife. 2018 Dec 18;7:e40070. doi: 10.7554/eLife.40070. Elife. 2018. PMID: 30561329 Free PMC article.
The glymphatic system is a brain-wide clearance pathway; its impairment contributes to the accumulation of amyloid-beta. ...
The glymphatic system is a brain-wide clearance pathway; its impairment contributes to the accumulation of amyloid-beta. ...
Loss of aquaporin-4 results in glymphatic system dysfunction via brain-wide interstitial fluid stagnation.
Gomolka RS, Hablitz LM, Mestre H, Giannetto M, Du T, Hauglund NL, Xie L, Peng W, Martinez PM, Nedergaard M, Mori Y. Gomolka RS, et al. Elife. 2023 Feb 9;12:e82232. doi: 10.7554/eLife.82232. Elife. 2023. PMID: 36757363 Free PMC article.
The glymphatic system is a fluid transport network of cerebrospinal fluid (CSF) entering the brain along arterial perivascular spaces, exchanging with interstitial fluid (ISF), ultimately establishing directional clearance of interstitial solutes. ...Mice with genetic dele …
The glymphatic system is a fluid transport network of cerebrospinal fluid (CSF) entering the brain along arterial perivascular spaces …
Circadian Mechanisms in Brain Fluid Biology.
Vizcarra VS, Fame RM, Hablitz LM. Vizcarra VS, et al. Circ Res. 2024 Mar 15;134(6):711-726. doi: 10.1161/CIRCRESAHA.123.323516. Epub 2024 Mar 14. Circ Res. 2024. PMID: 38484035 Review.
Cerebrospinal fluid contents are distinct from the general circulation because of regulation at brain barriers including the choroid plexus, glymphatic system, and blood-brain barrier. In this review, we discuss the overlapping circadian (24-hour) rhythms in brai …
Cerebrospinal fluid contents are distinct from the general circulation because of regulation at brain barriers including the choroid …
Glymphatic influx and clearance are accelerated by neurovascular coupling.
Holstein-Rønsbo S, Gan Y, Giannetto MJ, Rasmussen MK, Sigurdsson B, Beinlich FRM, Rose L, Untiet V, Hablitz LM, Kelley DH, Nedergaard M. Holstein-Rønsbo S, et al. Nat Neurosci. 2023 Jun;26(6):1042-1053. doi: 10.1038/s41593-023-01327-2. Epub 2023 Jun 1. Nat Neurosci. 2023. PMID: 37264158 Free PMC article.
Increased glymphatic influx is correlated with high EEG delta power and low heart rate in mice under anesthesia.
Hablitz LM, Vinitsky HS, Sun Q, Stæger FF, Sigurdsson B, Mortensen KN, Lilius TO, Nedergaard M. Hablitz LM, et al. Sci Adv. 2019 Feb 27;5(2):eaav5447. doi: 10.1126/sciadv.aav5447. eCollection 2019 Feb. Sci Adv. 2019. PMID: 30820460 Free PMC article.
The glymphatic system is responsible for brain-wide delivery of nutrients and clearance of waste via influx of cerebrospinal fluid (CSF) alongside perivascular spaces and through the brain. Glymphatic system activity increases during sleep or ketamine/xylazine (K/X) …
The glymphatic system is responsible for brain-wide delivery of nutrients and clearance of waste via influx of cerebrospinal fluid (C …
The glymphatic system.
Hablitz LM, Nedergaard M. Hablitz LM, et al. Curr Biol. 2021 Oct 25;31(20):R1371-R1375. doi: 10.1016/j.cub.2021.08.026. Curr Biol. 2021. PMID: 34699796 Free article.
A real-time in vivo clearance assay for quantification of glymphatic efflux.
Plá V, Bork P, Harnpramukkul A, Olveda G, Ladrón-de-Guevara A, Giannetto MJ, Hussain R, Wang W, Kelley DH, Hablitz LM, Nedergaard M. Plá V, et al. Cell Rep. 2022 Sep 13;40(11):111320. doi: 10.1016/j.celrep.2022.111320. Cell Rep. 2022. PMID: 36103828 Free article.
Glymphatic fluid transport eliminates metabolic waste from the brain including amyloid-beta, yet the methodology for studying efflux remains rudimentary. ...This in vivo methodology will aid in defining the physiological variables that drive efflux, as well as the impact o …
Glymphatic fluid transport eliminates metabolic waste from the brain including amyloid-beta, yet the methodology for studying efflux …
154 results