Nadel JA - Search Results

1

Isolated abnormal FEF75% detects unsuspected bronchiolar obstruction in CF children.

Masson VK, Nussbaum E, Gelb AF, Tashkin DP, Randhawa I, Nadel JA, Fireizen Y, De Celie-Germana JK, Madera D, Senanayake D. Masson VK, et al. Among authors: nadel ja. Pediatr Res. 2023 Sep;94(3):1051-1056. doi: 10.1038/s41390-023-02532-2. Epub 2023 Mar 13. Pediatr Res. 2023. PMID: 36914809

2

Characterization of striatal dopamine projections across striatal subregions in behavioral flexibility.

van der Merwe RK, Nadel JA, Copes-Finke D, Pawelko S, Scott JS, Ghanem M, Fox M, Morehouse C, McLaughlin R, Maddox C, Albert-Lyons R, Malaki G, Groce V, Turocy A, Aggadi N, Jin X, Howard CD. van der Merwe RK, et al. Among authors: nadel ja. Eur J Neurosci. 2023 Dec;58(12):4466-4486. doi: 10.1111/ejn.15910. Epub 2023 Jan 22. Eur J Neurosci. 2023. PMID: 36617434

3

The effect of selective nigrostriatal dopamine excess on behaviors linked to the cognitive and negative symptoms of schizophrenia.

Moya NA, Yun S, Fleps SW, Martin MM, Nadel JA, Beutler LR, Zweifel LS, Parker JG. Moya NA, et al. Among authors: nadel ja. Neuropsychopharmacology. 2023 Mar;48(4):690-699. doi: 10.1038/s41386-022-01492-1. Epub 2022 Nov 15. Neuropsychopharmacology. 2023. PMID: 36380221 Free PMC article.

4

Chronic Ethanol Consumption Alters Presynaptic Regulation of Dorsal Striatal Dopamine Release in C57BL/6J Mice.

Salinas AG, Nadel JA, Mateo Y, Huynh T, Augustin SM, Pacak K, Lovinger DM. Salinas AG, et al. Among authors: nadel ja. Int J Mol Sci. 2022 Sep 20;23(19):10994. doi: 10.3390/ijms231910994. Int J Mol Sci. 2022. PMID: 36232321 Free PMC article.

5

Optogenetic stimulation of striatal patches modifies habit formation and inhibits dopamine release.

Nadel JA, Pawelko SS, Scott JR, McLaughlin R, Fox M, Ghanem M, van der Merwe R, Hollon NG, Ramsson ES, Howard CD. Nadel JA, et al. Sci Rep. 2021 Oct 6;11(1):19847. doi: 10.1038/s41598-021-99350-5. Sci Rep. 2021. PMID: 34615966 Free PMC article.

6

Normal Routine Spirometry Can Mask COPD/Emphysema in Symptomatic Smokers.

Gelb AF, Yamamoto A, Verbeken EK, Hogg JC, Tashkin DP, Tran DNT, Moridzadeh RM, Fraser C, Schein MJ, Decramer M, Glassy EF, Nadel JA. Gelb AF, et al. Among authors: nadel ja. Chronic Obstr Pulm Dis. 2021 Jan;8(1):124-34. doi: 10.15326/jcopdf.2020.0176. Chronic Obstr Pulm Dis. 2021. PMID: 33513660 Free PMC article.

7

Asthma and emphysema overlap in nonsmokers.

Gelb AF, Yamamoto A, Verbeken E, Grigorian SR, Nadel JA. Gelb AF, et al. Among authors: nadel ja. Ann Allergy Asthma Immunol. 2020 Dec;125(6):711-713. doi: 10.1016/j.anai.2020.08.010. Epub 2020 Aug 10. Ann Allergy Asthma Immunol. 2020. PMID: 32791102 No abstract available.

8

Lesion of striatal patches disrupts habitual behaviors and increases behavioral variability.

Nadel JA, Pawelko SS, Copes-Finke D, Neidhart M, Howard CD. Nadel JA, et al. PLoS One. 2020 Jan 8;15(1):e0224715. doi: 10.1371/journal.pone.0224715. eCollection 2020. PLoS One. 2020. PMID: 31914121 Free PMC article.

9

Respiratory syncytial virus activates epidermal growth factor receptor to suppress interferon regulatory factor 1-dependent interferon-lambda and antiviral defense in airway epithelium.

Kalinowski A, Galen BT, Ueki IF, Sun Y, Mulenos A, Osafo-Addo A, Clark B, Joerns J, Liu W, Nadel JA, Dela Cruz CS, Koff JL. Kalinowski A, et al. Among authors: nadel ja. Mucosal Immunol. 2018 May;11(3):958-967. doi: 10.1038/mi.2017.120. Epub 2018 Feb 7. Mucosal Immunol. 2018. PMID: 29411775 Free PMC article.

10

Further Studies of Unsuspected Emphysema in Nonsmoking Patients With Asthma With Persistent Expiratory Airflow Obstruction.

Gelb AF, Yamamoto A, Verbeken EK, Schein MJ, Moridzadeh R, Tran D, Fraser C, Barbers R, Elatre W, Koss MN, Glassy EF, Nadel JA. Gelb AF, et al. Among authors: nadel ja. Chest. 2018 Mar;153(3):618-629. doi: 10.1016/j.chest.2017.11.016. Epub 2017 Nov 29. Chest. 2018. PMID: 29197547

11

Affirmation of the adoration of the vagi and role of tiotropium in asthmatic patients.

Gelb AF, Nadel JA. Gelb AF, et al. Among authors: nadel ja. J Allergy Clin Immunol. 2016 Oct;138(4):1011-1013. doi: 10.1016/j.jaci.2016.06.024. Epub 2016 Jul 22. J Allergy Clin Immunol. 2016. PMID: 27527265 Review. No abstract available.

12

Understanding the pathophysiology of the asthma-chronic obstructive pulmonary disease overlap syndrome.

Gelb AF, Christenson SA, Nadel JA. Gelb AF, et al. Among authors: nadel ja. Curr Opin Pulm Med. 2016 Mar;22(2):100-5. doi: 10.1097/MCP.0000000000000236. Curr Opin Pulm Med. 2016. PMID: 26717511 Review.

13

Understanding the pathophysiology of the asthma-chronic obstructive pulmonary disease overlap syndrome.

Gelb AF, Nadel JA. Gelb AF, et al. Among authors: nadel ja. J Allergy Clin Immunol. 2015 Sep;136(3):553-5. doi: 10.1016/j.jaci.2015.06.013. J Allergy Clin Immunol. 2015. PMID: 26343939 No abstract available.

14

Unraveling the Pathophysiology of the Asthma-COPD Overlap Syndrome: Unsuspected Mild Centrilobular Emphysema Is Responsible for Loss of Lung Elastic Recoil in Never Smokers With Asthma With Persistent Expiratory Airflow Limitation.

Gelb AF, Yamamoto A, Verbeken EK, Nadel JA. Gelb AF, et al. Among authors: nadel ja. Chest. 2015 Aug;148(2):313-320. doi: 10.1378/chest.14-2483. Chest. 2015. PMID: 25950858

15

EGFR activation suppresses respiratory virus-induced IRF1-dependent CXCL10 production.

Kalinowski A, Ueki I, Min-Oo G, Ballon-Landa E, Knoff D, Galen B, Lanier LL, Nadel JA, Koff JL. Kalinowski A, et al. Among authors: nadel ja. Am J Physiol Lung Cell Mol Physiol. 2014 Jul 15;307(2):L186-96. doi: 10.1152/ajplung.00368.2013. Epub 2014 May 16. Am J Physiol Lung Cell Mol Physiol. 2014. PMID: 24838750 Free PMC article.

16

The CFTR and EGFR relationship in airway vascular growth, and its importance in cystic fibrosis.

Nadel JA. Nadel JA. Eur Respir J. 2013 Dec;42(6):1438-40. doi: 10.1183/09031936.00107513. Eur Respir J. 2013. PMID: 24293414 Free article. No abstract available.

17

Unsuspected mild emphysema in nonsmoking patients with chronic asthma with persistent airway obstruction.

Gelb AF, Yamamoto A, Mauad T, Kollin J, Schein MJ, Nadel JA. Gelb AF, et al. Among authors: nadel ja. J Allergy Clin Immunol. 2014 Jan;133(1):263-5.e1-3. doi: 10.1016/j.jaci.2013.09.045. Epub 2013 Nov 28. J Allergy Clin Immunol. 2014. PMID: 24290280 No abstract available.

18

Respiratory virus-induced EGFR activation suppresses IRF1-dependent interferon λ and antiviral defense in airway epithelium.

Ueki IF, Min-Oo G, Kalinowski A, Ballon-Landa E, Lanier LL, Nadel JA, Koff JL. Ueki IF, et al. Among authors: nadel ja. J Exp Med. 2013 Sep 23;210(10):1929-36. doi: 10.1084/jem.20121401. Epub 2013 Sep 2. J Exp Med. 2013. PMID: 23999497 Free PMC article.

19

Normal CFTR inhibits epidermal growth factor receptor-dependent pro-inflammatory chemokine production in human airway epithelial cells.

Kim S, Beyer BA, Lewis C, Nadel JA. Kim S, et al. Among authors: nadel ja. PLoS One. 2013 Aug 16;8(8):e72981. doi: 10.1371/journal.pone.0072981. eCollection 2013. PLoS One. 2013. PMID: 23977375 Free PMC article.

20

John Widdicombe's contribution to respiratory physiology and cough: reminiscences.

Chung KF, Nadel JA, Fontana G. Chung KF, et al. Among authors: nadel ja. Cough. 2013 Mar 6;9(1):6. doi: 10.1186/1745-9974-9-6. Cough. 2013. PMID: 23497652 Free PMC article.

21

Mucous hypersecretion and relationship to cough.

Nadel JA. Nadel JA. Pulm Pharmacol Ther. 2013 Oct;26(5):510-3. doi: 10.1016/j.pupt.2013.02.003. Epub 2013 Feb 19. Pulm Pharmacol Ther. 2013. PMID: 23434445

22

Epidermal growth factor receptor reactivation induced by E-prostanoid-3 receptor- and tumor necrosis factor-alpha-converting enzyme-dependent feedback exaggerates interleukin-8 production in airway cancer (NCI-H292) cells.

Kim S, Lewis C, Nadel JA. Kim S, et al. Among authors: nadel ja. Exp Cell Res. 2011 Nov 1;317(18):2650-60. doi: 10.1016/j.yexcr.2011.08.023. Epub 2011 Sep 7. Exp Cell Res. 2011. PMID: 21925169

23

CCL20/CCR6 feedback exaggerates epidermal growth factor receptor-dependent MUC5AC mucin production in human airway epithelial (NCI-H292) cells.

Kim S, Lewis C, Nadel JA. Kim S, et al. Among authors: nadel ja. J Immunol. 2011 Mar 15;186(6):3392-400. doi: 10.4049/jimmunol.1003377. Epub 2011 Feb 7. J Immunol. 2011. PMID: 21300824

24

Plugging (publicising) to prevent mucous plugging.

Burgel PR, Nadel JA. Burgel PR, et al. Among authors: nadel ja. Eur Respir J. 2010 Dec;36(6):1236-8. doi: 10.1183/09031936.00100610. Eur Respir J. 2010. PMID: 21119202 Free article. No abstract available.

25

Twenty-five years of airway research: personal thoughts.

Nadel JA. Nadel JA. Proc Am Thorac Soc. 2010 Nov;7(6):338-42. doi: 10.1513/pats.201001-013AW. Proc Am Thorac Soc. 2010. PMID: 21030510

26

Alternative mechanisms for tiotropium.

Bateman ED, Rennard S, Barnes PJ, Dicpinigaitis PV, Gosens R, Gross NJ, Nadel JA, Pfeifer M, Racké K, Rabe KF, Rubin BK, Welte T, Wessler I. Bateman ED, et al. Among authors: nadel ja. Pulm Pharmacol Ther. 2009 Dec;22(6):533-42. doi: 10.1016/j.pupt.2009.06.002. Epub 2009 Jul 25. Pulm Pharmacol Ther. 2009. PMID: 19635581 Review.

27

Fibrinogen binding to ICAM-1 promotes EGFR-dependent mucin production in human airway epithelial cells.

Kim S, Nadel JA. Kim S, et al. Among authors: nadel ja. Am J Physiol Lung Cell Mol Physiol. 2009 Jul;297(1):L174-83. doi: 10.1152/ajplung.00032.2009. Epub 2009 May 8. Am J Physiol Lung Cell Mol Physiol. 2009. PMID: 19429776 Free PMC article.

28

Lipopolysaccharide initiates a positive feedback of epidermal growth factor receptor signaling by prostaglandin E2 in human biliary carcinoma cells.

Finzi L, Shao MX, Paye F, Housset C, Nadel JA. Finzi L, et al. Among authors: nadel ja. J Immunol. 2009 Feb 15;182(4):2269-76. doi: 10.4049/jimmunol.0801768. J Immunol. 2009. PMID: 19201881

29

Epidermal growth factor receptor-mediated innate immune responses and their roles in airway diseases.

Burgel PR, Nadel JA. Burgel PR, et al. Among authors: nadel ja. Eur Respir J. 2008 Oct;32(4):1068-81. doi: 10.1183/09031936.00172007. Eur Respir J. 2008. PMID: 18827153 Free article. Review.

30

Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium.

Koff JL, Shao MX, Ueki IF, Nadel JA. Koff JL, et al. Among authors: nadel ja. Am J Physiol Lung Cell Mol Physiol. 2008 Jun;294(6):L1068-75. doi: 10.1152/ajplung.00025.2008. Epub 2008 Mar 28. Am J Physiol Lung Cell Mol Physiol. 2008. PMID: 18375743 Free article.

31

Efficacy and safety of formoterol for the treatment of chronic obstructive pulmonary disease.

Berger WE, Nadel JA. Berger WE, et al. Among authors: nadel ja. Respir Med. 2008 Feb;102(2):173-88. doi: 10.1016/j.rmed.2007.09.011. Epub 2007 Nov 19. Respir Med. 2008. PMID: 18023995 Free article. Review.

32

Acrolein-activated matrix metalloproteinase 9 contributes to persistent mucin production.

Deshmukh HS, Shaver C, Case LM, Dietsch M, Wesselkamper SC, Hardie WD, Korfhagen TR, Corradi M, Nadel JA, Borchers MT, Leikauf GD. Deshmukh HS, et al. Among authors: nadel ja. Am J Respir Cell Mol Biol. 2008 Apr;38(4):446-54. doi: 10.1165/rcmb.2006-0339OC. Epub 2007 Nov 15. Am J Respir Cell Mol Biol. 2008. PMID: 18006877 Free PMC article.

33

Regulation of interleukin-8 via an airway epithelial signaling cascade.

Nakanaga T, Nadel JA, Ueki IF, Koff JL, Shao MX. Nakanaga T, et al. Among authors: nadel ja. Am J Physiol Lung Cell Mol Physiol. 2007 May;292(5):L1289-96. doi: 10.1152/ajplung.00356.2006. Epub 2007 Jan 12. Am J Physiol Lung Cell Mol Physiol. 2007. PMID: 17220369 Free article.

34

Innate immune mucin production via epithelial cell surface signaling: relationship to allergic disease.

Nadel JA. Nadel JA. Curr Opin Allergy Clin Immunol. 2007 Feb;7(1):57-62. doi: 10.1097/ACI.0b013e328012ce22. Curr Opin Allergy Clin Immunol. 2007. PMID: 17218812 Review.

35

MUC5AC, a gel-forming mucin accumulating in gallstone disease, is overproduced via an epidermal growth factor receptor pathway in the human gallbladder.

Finzi L, Barbu V, Burgel PR, Mergey M, Kirkwood KS, Wick EC, Scoazec JY, Peschaud F, Paye F, Nadel JA, Housset C. Finzi L, et al. Among authors: nadel ja. Am J Pathol. 2006 Dec;169(6):2031-41. doi: 10.2353/ajpath.2006.060146. Am J Pathol. 2006. PMID: 17148666 Free PMC article.

36

Pseudomonas lipopolysaccharide accelerates wound repair via activation of a novel epithelial cell signaling cascade.

Koff JL, Shao MX, Kim S, Ueki IF, Nadel JA. Koff JL, et al. Among authors: nadel ja. J Immunol. 2006 Dec 15;177(12):8693-700. doi: 10.4049/jimmunol.177.12.8693. J Immunol. 2006. PMID: 17142770

37

A morphometric study of mucins and small airway plugging in cystic fibrosis.

Burgel PR, Montani D, Danel C, Dusser DJ, Nadel JA. Burgel PR, et al. Among authors: nadel ja. Thorax. 2007 Feb;62(2):153-61. doi: 10.1136/thx.2006.062190. Epub 2006 Aug 23. Thorax. 2007. PMID: 16928707 Free PMC article.

38

Neutrophil elastase induces MUC5AC mucin production in human airway epithelial cells via a cascade involving protein kinase C, reactive oxygen species, and TNF-alpha-converting enzyme.

Shao MX, Nadel JA. Shao MX, et al. Among authors: nadel ja. J Immunol. 2005 Sep 15;175(6):4009-16. doi: 10.4049/jimmunol.175.6.4009. J Immunol. 2005. PMID: 16148149

39

E-cadherin promotes EGFR-mediated cell differentiation and MUC5AC mucin expression in cultured human airway epithelial cells.

Kim S, Schein AJ, Nadel JA. Kim S, et al. Among authors: nadel ja. Am J Physiol Lung Cell Mol Physiol. 2005 Dec;289(6):L1049-60. doi: 10.1152/ajplung.00388.2004. Epub 2005 Jul 29. Am J Physiol Lung Cell Mol Physiol. 2005. PMID: 16055478 Free article.

40

Dual oxidase 1-dependent MUC5AC mucin expression in cultured human airway epithelial cells.

Shao MX, Nadel JA. Shao MX, et al. Among authors: nadel ja. Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):767-72. doi: 10.1073/pnas.0408932102. Epub 2005 Jan 7. Proc Natl Acad Sci U S A. 2005. PMID: 15640347 Free PMC article.

41

Metalloproteinases mediate mucin 5AC expression by epidermal growth factor receptor activation.

Deshmukh HS, Case LM, Wesselkamper SC, Borchers MT, Martin LD, Shertzer HG, Nadel JA, Leikauf GD. Deshmukh HS, et al. Among authors: nadel ja. Am J Respir Crit Care Med. 2005 Feb 15;171(4):305-14. doi: 10.1164/rccm.200408-1003OC. Epub 2004 Nov 5. Am J Respir Crit Care Med. 2005. PMID: 15531749

42

Roles of epidermal growth factor receptor activation in epithelial cell repair and mucin production in airway epithelium.

Burgel PR, Nadel JA. Burgel PR, et al. Among authors: nadel ja. Thorax. 2004 Nov;59(11):992-6. doi: 10.1136/thx.2003.018879. Thorax. 2004. PMID: 15516478 Free PMC article. Review.

43

Intranasal steroids decrease eosinophils but not mucin expression in nasal polyps.

Burgel PR, Cardell LO, Ueki IF, Nadel JA. Burgel PR, et al. Among authors: nadel ja. Eur Respir J. 2004 Oct;24(4):594-600. doi: 10.1183/09031936.04.00014404. Eur Respir J. 2004. PMID: 15459138 Free article.

44

Role of neutrophils in mucus hypersecretion in COPD and implications for therapy.

Kim S, Nadel JA. Kim S, et al. Among authors: nadel ja. Treat Respir Med. 2004;3(3):147-59. doi: 10.2165/00151829-200403030-00003. Treat Respir Med. 2004. PMID: 15219174 Review.

45

Cigarette smoke induces MUC5AC mucin overproduction via tumor necrosis factor-alpha-converting enzyme in human airway epithelial (NCI-H292) cells.

Shao MX, Nakanaga T, Nadel JA. Shao MX, et al. Among authors: nadel ja. Am J Physiol Lung Cell Mol Physiol. 2004 Aug;287(2):L420-7. doi: 10.1152/ajplung.00019.2004. Epub 2004 Apr 30. Am J Physiol Lung Cell Mol Physiol. 2004. PMID: 15121636 Free article.

46

fMLP causes degranulation followed by regranulation in rat nasal glands.

Kim ST, Nakanaga T, Ueki I, Nadel JA. Kim ST, et al. Among authors: nadel ja. Laryngoscope. 2003 Nov;113(11):1998-2003. doi: 10.1097/00005537-200311000-00027. Laryngoscope. 2003. PMID: 14603063

47

Tumor necrosis factor alpha-converting enzyme mediates MUC5AC mucin expression in cultured human airway epithelial cells.

Shao MX, Ueki IF, Nadel JA. Shao MX, et al. Among authors: nadel ja. Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11618-23. doi: 10.1073/pnas.1534804100. Epub 2003 Sep 12. Proc Natl Acad Sci U S A. 2003. PMID: 12972643 Free PMC article.

48

Pseudomonas aeruginosa induces MUC5AC production via epidermal growth factor receptor.

Kohri K, Ueki IF, Shim JJ, Burgel PR, Oh YM, Tam DC, Dao-Pick T, Nadel JA. Kohri K, et al. Among authors: nadel ja. Eur Respir J. 2002 Nov;20(5):1263-70. doi: 10.1183/09031936.02.00001402. Eur Respir J. 2002. PMID: 12449183 Free article.

49

Neutrophil elastase induces mucin production by ligand-dependent epidermal growth factor receptor activation.

Kohri K, Ueki IF, Nadel JA. Kohri K, et al. Among authors: nadel ja. Am J Physiol Lung Cell Mol Physiol. 2002 Sep;283(3):L531-40. doi: 10.1152/ajplung.00455.2001. Am J Physiol Lung Cell Mol Physiol. 2002. PMID: 12169572 Free article.

50

IL-13-induced Clara cell secretory protein expression in airway epithelium: role of EGFR signaling pathway.

Kim S, Shim JJ, Burgel PR, Ueki IF, Dao-Pick T, Tam DC, Nadel JA. Kim S, et al. Among authors: nadel ja. Am J Physiol Lung Cell Mol Physiol. 2002 Jul;283(1):L67-75. doi: 10.1152/ajplung.00404.2001. Am J Physiol Lung Cell Mol Physiol. 2002. PMID: 12060562 Free article.

51

The role of epidermal growth factor in mucus production.

Nadel JA, Burgel PR. Nadel JA, et al. Curr Opin Pharmacol. 2001 Jun;1(3):254-8. doi: 10.1016/s1471-4892(01)00045-5. Curr Opin Pharmacol. 2001. PMID: 11712748 Review.

52

Human eosinophils induce mucin production in airway epithelial cells via epidermal growth factor receptor activation.

Burgel PR, Lazarus SC, Tam DC, Ueki IF, Atabai K, Birch M, Nadel JA. Burgel PR, et al. Among authors: nadel ja. J Immunol. 2001 Nov 15;167(10):5948-54. doi: 10.4049/jimmunol.167.10.5948. J Immunol. 2001. PMID: 11698473

53

Role of epidermal growth factor receptor activation in regulating mucin synthesis.

Nadel JA. Nadel JA. Respir Res. 2001;2(2):85-9. doi: 10.1186/rr43. Epub 2001 Feb 21. Respir Res. 2001. PMID: 11686870 Free PMC article. Review.

54

Epidermal growth factor receptor signaling mediates regranulation of rat nasal goblet cells.

Lee HM, Malm L, Dabbagh K, Dao-Pick T, Ueki IF, Kim S, Shim JJ, Nadel JA. Lee HM, et al. Among authors: nadel ja. J Allergy Clin Immunol. 2001 Jun;107(6):1046-50. doi: 10.1067/mai.2001.115140. J Allergy Clin Immunol. 2001. PMID: 11398083

55

Relationship of epidermal growth factor receptors to goblet cell production in human bronchi.

Takeyama K, Fahy JV, Nadel JA. Takeyama K, et al. Among authors: nadel ja. Am J Respir Crit Care Med. 2001 Feb;163(2):511-6. doi: 10.1164/ajrccm.163.2.2001038. Am J Respir Crit Care Med. 2001. PMID: 11179132

56

Activation of epidermal growth factor receptors is responsible for mucin synthesis induced by cigarette smoke.

Takeyama K, Jung B, Shim JJ, Burgel PR, Dao-Pick T, Ueki IF, Protin U, Kroschel P, Nadel JA. Takeyama K, et al. Among authors: nadel ja. Am J Physiol Lung Cell Mol Physiol. 2001 Jan;280(1):L165-72. doi: 10.1152/ajplung.2001.280.1.L165. Am J Physiol Lung Cell Mol Physiol. 2001. PMID: 11133506 Free article.

57

IL-13 induces mucin production by stimulating epidermal growth factor receptors and by activating neutrophils.

Shim JJ, Dabbagh K, Ueki IF, Dao-Pick T, Burgel PR, Takeyama K, Tam DC, Nadel JA. Shim JJ, et al. Among authors: nadel ja. Am J Physiol Lung Cell Mol Physiol. 2001 Jan;280(1):L134-40. doi: 10.1152/ajplung.2001.280.1.L134. Am J Physiol Lung Cell Mol Physiol. 2001. PMID: 11133503 Free article.

58

Nitric oxide-dependent neutrophil recruitment: role in nasal secretion.

Cardell LO, Agustí C, Nadel JA. Cardell LO, et al. Among authors: nadel ja. Clin Exp Allergy. 2000 Dec;30(12):1799-803. doi: 10.1046/j.1365-2222.2000.00984.x. Clin Exp Allergy. 2000. PMID: 11122220

59

Nasal secretion in ragweed-sensitized dogs: effect of leukotriene synthesis inhibition.

Cardell LO, Agustí C, Nadel JA. Cardell LO, et al. Among authors: nadel ja. Acta Otolaryngol. 2000 Sep;120(6):757-60. doi: 10.1080/000164800750000306. Acta Otolaryngol. 2000. PMID: 11099154

60

Relation of epidermal growth factor receptor expression to goblet cell hyperplasia in nasal polyps.

Burgel PR, Escudier E, Coste A, Dao-Pick T, Ueki IF, Takeyama K, Shim JJ, Murr AH, Nadel JA. Burgel PR, et al. Among authors: nadel ja. J Allergy Clin Immunol. 2000 Oct;106(4):705-12. doi: 10.1067/mai.2000.109823. J Allergy Clin Immunol. 2000. PMID: 11031341

61

Role of neutrophil elastase in hypersecretion during COPD exacerbations, and proposed therapies.

Nadel JA. Nadel JA. Chest. 2000 May;117(5 Suppl 2):386S-9S. doi: 10.1378/chest.117.5_suppl_2.386s. Chest. 2000. PMID: 10843982 Review.

62

Mechanisms of airway hypersecretion and novel therapy.

Nadel JA. Nadel JA. Chest. 2000 May;117(5 Suppl 1):262S-6S. doi: 10.1378/chest.117.5_suppl_1.262s-a. Chest. 2000. PMID: 10843942 No abstract available.

63

Role of neutrophil elastase in hypersecretion in asthma.

Nadel JA, Takeyama K, Agustí C. Nadel JA, et al. Eur Respir J. 1999 Jan;13(1):190-6. doi: 10.1034/j.1399-3003.1999.13a35.x. Eur Respir J. 1999. PMID: 10836347 Free article.

64

Suplatast tosilate inhibits goblet-cell metaplasia of airway epithelium in sensitized mice.

Shim JJ, Dabbagh K, Takeyama K, Burgel PR, Dao-Pick TP, Ueki IF, Nadel JA. Shim JJ, et al. Among authors: nadel ja. J Allergy Clin Immunol. 2000 Apr;105(4):739-45. doi: 10.1067/mai.2000.105221. J Allergy Clin Immunol. 2000. PMID: 10756224

65

Role of nitric oxide and septide-insensitive NK(1) receptors in bronchoconstriction induced by aerosolised neurokinin A in guinea-pigs.

Ricciardolo FL, Trevisani M, Geppetti P, Nadel JA, Amadesi S, Bertrand C. Ricciardolo FL, et al. Among authors: nadel ja. Br J Pharmacol. 2000 Mar;129(5):915-20. doi: 10.1038/sj.bjp.0703135. Br J Pharmacol. 2000. PMID: 10696090 Free PMC article.

66

Agarose plug instillation causes goblet cell metaplasia by activating EGF receptors in rat airways.

Lee HM, Takeyama K, Dabbagh K, Lausier JA, Ueki IF, Nadel JA. Lee HM, et al. Among authors: nadel ja. Am J Physiol Lung Cell Mol Physiol. 2000 Jan;278(1):L185-92. doi: 10.1152/ajplung.2000.278.1.L185. Am J Physiol Lung Cell Mol Physiol. 2000. PMID: 10645906 Free article.

67

Oxidative stress causes mucin synthesis via transactivation of epidermal growth factor receptor: role of neutrophils.

Takeyama K, Dabbagh K, Jeong Shim J, Dao-Pick T, Ueki IF, Nadel JA. Takeyama K, et al. Among authors: nadel ja. J Immunol. 2000 Feb 1;164(3):1546-52. doi: 10.4049/jimmunol.164.3.1546. J Immunol. 2000. PMID: 10640773

68

Nitric oxide synthase inhibitors attenuate ozone-induced airway inflammation in guinea pigs. Possible role of interleukin-8.

Inoue H, Aizawa H, Nakano H, Matsumoto K, Kuwano K, Nadel JA, Hara N. Inoue H, et al. Among authors: nadel ja. Am J Respir Crit Care Med. 2000 Jan;161(1):249-56. doi: 10.1164/ajrccm.161.1.9804096. Am J Respir Crit Care Med. 2000. PMID: 10619828

69

Bronchodilation by pituitary adenylate cyclase-activating peptide and related peptides.

Lindén A, Cardell LO, Yoshihara S, Nadel JA. Lindén A, et al. Among authors: nadel ja. Eur Respir J. 1999 Aug;14(2):443-51. doi: 10.1034/j.1399-3003.1999.14b34.x. Eur Respir J. 1999. PMID: 10515428 Free article. Review.

70

LTB(4)-induced nasal gland serous cell secretion mediated by neutrophil elastase.

Cardell LO, Agustí C, Takeyama K, Stjärne P, Nadel JA. Cardell LO, et al. Among authors: nadel ja. Am J Respir Crit Care Med. 1999 Aug;160(2):411-4. doi: 10.1164/ajrccm.160.2.9808117. Am J Respir Crit Care Med. 1999. PMID: 10430706

71

IL-4 induces mucin gene expression and goblet cell metaplasia in vitro and in vivo.

Dabbagh K, Takeyama K, Lee HM, Ueki IF, Lausier JA, Nadel JA. Dabbagh K, et al. Among authors: nadel ja. J Immunol. 1999 May 15;162(10):6233-7. J Immunol. 1999. PMID: 10229869

72

Carbon monoxide, a cyclic GMP-related messenger, involved in hypoxic bronchodilation in vivo.

Cardell LO, Lou YP, Takeyama K, Ueki IF, Lausier J, Nadel JA. Cardell LO, et al. Among authors: nadel ja. Pulm Pharmacol Ther. 1998;11(4):309-15. doi: 10.1006/pupt.1998.0152. Pulm Pharmacol Ther. 1998. PMID: 10101749

73

Proteinase 3, a potent secretagogue in airways, is present in cystic fibrosis sputum.

Witko-Sarsat V, Halbwachs-Mecarelli L, Schuster A, Nusbaum P, Ueki I, Canteloup S, Lenoir G, Descamps-Latscha B, Nadel JA. Witko-Sarsat V, et al. Among authors: nadel ja. Am J Respir Cell Mol Biol. 1999 Apr;20(4):729-36. doi: 10.1165/ajrcmb.20.4.3371. Am J Respir Cell Mol Biol. 1999. PMID: 10101005

74

Mechanisms of hypersecretion in acute asthma, proposed cause of death, and novel therapy.

Nadel JA, Takeyama K. Nadel JA, et al. Pediatr Pulmonol Suppl. 1999;18:54-5. Pediatr Pulmonol Suppl. 1999. PMID: 10093095

75

Epidermal growth factor system regulates mucin production in airways.

Takeyama K, Dabbagh K, Lee HM, Agustí C, Lausier JA, Ueki IF, Grattan KM, Nadel JA. Takeyama K, et al. Among authors: nadel ja. Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):3081-6. doi: 10.1073/pnas.96.6.3081. Proc Natl Acad Sci U S A. 1999. PMID: 10077640 Free PMC article.

76

Proteolytic enzymes and airway diseases.

Nadel JA, Stockley RA. Nadel JA, et al. Eur Respir J. 1998 Dec;12(6):1250-1. doi: 10.1183/09031936.98.12061250. Eur Respir J. 1998. PMID: 9877472 Free article. No abstract available.

77

Goblet cell degranulation after antigen challenge in sensitized guinea pigs. Role of neutrophils.

Agusti C, Takeyama K, Cardell LO, Ueki I, Lausier J, Lou YP, Nadel JA. Agusti C, et al. Among authors: nadel ja. Am J Respir Crit Care Med. 1998 Oct;158(4):1253-8. doi: 10.1164/ajrccm.158.4.9801041. Am J Respir Crit Care Med. 1998. PMID: 9769289

78

Bronchodilatation in vivo by carbon monoxide, a cyclic GMP related messenger.

Cardell LO, Ueki IF, Stjärne P, Agusti C, Takeyama K, Lindén A, Nadel JA. Cardell LO, et al. Among authors: nadel ja. Br J Pharmacol. 1998 Jul;124(6):1065-8. doi: 10.1038/sj.bjp.0701878. Br J Pharmacol. 1998. PMID: 9720774 Free PMC article.

79

Neutrophil-dependent goblet cell degranulation: role of membrane-bound elastase and adhesion molecules.

Takeyama K, Agustí C, Ueki I, Lausier J, Cardell LO, Nadel JA. Takeyama K, et al. Among authors: nadel ja. Am J Physiol. 1998 Aug;275(2):L294-302. doi: 10.1152/ajplung.1998.275.2.L294. Am J Physiol. 1998. PMID: 9700090

80

Bradykinin increases intracellular calcium levels in a human bronchial epithelial cell line via the B2 receptor subtype.

Ricciardolo FL, Lovett M, Halliday DA, Nadel JA, Kaneko T, Bunnett NW, Geppetti P. Ricciardolo FL, et al. Among authors: nadel ja. Inflamm Res. 1998 May;47(5):231-5. doi: 10.1007/s000110050322. Inflamm Res. 1998. PMID: 9657256

81

Platelet-activating factor induces goblet cell hyperplasia and mucin gene expression in airways.

Lou YP, Takeyama K, Grattan KM, Lausier JA, Ueki IF, Agustí C, Nadel JA. Lou YP, et al. Among authors: nadel ja. Am J Respir Crit Care Med. 1998 Jun;157(6 Pt 1):1927-34. doi: 10.1164/ajrccm.157.6.9709113. Am J Respir Crit Care Med. 1998. PMID: 9620929

82

Asthma.

Nadel JA, Busse WW. Nadel JA, et al. Am J Respir Crit Care Med. 1998 Apr;157(4 Pt 2):S130-8. doi: 10.1164/ajrccm.157.4.nhlb1-11. Am J Respir Crit Care Med. 1998. PMID: 9563772 Review. No abstract available.

83

Inhibition of tracheal vascular extravasation by liposome-encapsulated albuterol in rats.

Zhang W, Guo L, Nadel JA, Papahadjopoulos D. Zhang W, et al. Among authors: nadel ja. Pharm Res. 1998 Mar;15(3):455-60. doi: 10.1023/a:1011984500787. Pharm Res. 1998. PMID: 9563077

84

Endogenous nitric oxide inhibits bronchoconstriction induced by cold-air inhalation in guinea pigs: role of kinins.

Yoshihara S, Nadel JA, Figini M, Emanueli C, Pradelles P, Geppetti P. Yoshihara S, et al. Among authors: nadel ja. Am J Respir Crit Care Med. 1998 Feb;157(2):547-52. doi: 10.1164/ajrccm.157.2.9704074. Am J Respir Crit Care Med. 1998. PMID: 9476871

85

PACAP 1-38 as an inhaled bronchodilator in guinea pigs in vivo.

Lindén A, Cardell LO, Yoshihara S, Stjärne P, Nadel JA. Lindén A, et al. Among authors: nadel ja. Peptides. 1998;19(1):93-8. doi: 10.1016/s0196-9781(97)00256-8. Peptides. 1998. PMID: 9437741

86

A method for canine nasal mucosa superfusion, in vivo; evidence that pseudomonas-induced neutrophil migration is inhibited by alpha2-adrenoceptor agonist.

Stjärne P, Agusti C, Cardell LO, Wagstaff S, Nadel JA. Stjärne P, et al. Among authors: nadel ja. Clin Exp Allergy. 1997 Dec;27(12):1471-6. Clin Exp Allergy. 1997. PMID: 9433943

87

PACAP-induced plasma extravasation in rat skin.

Cardell LO, Stjärne P, Wagstaff SJ, Agustí C, Nadel JA. Cardell LO, et al. Among authors: nadel ja. Regul Pept. 1997 Aug 15;71(2):67-71. doi: 10.1016/s0167-0115(97)00027-x. Regul Pept. 1997. PMID: 9416988

88

Long lasting smooth muscle relaxation by a novel PACAP analogue in guinea-pig and primate airways in vitro.

Yoshihara S, Lindén A, Kashimoto K, Nagano Y, Ichimura T, Nadel JA. Yoshihara S, et al. Among authors: nadel ja. Br J Pharmacol. 1997 Aug;121(8):1730-4. doi: 10.1038/sj.bjp.0701310. Br J Pharmacol. 1997. PMID: 9283710 Free PMC article.

89

Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease.

Li JD, Dohrman AF, Gallup M, Miyata S, Gum JR, Kim YS, Nadel JA, Prince A, Basbaum CB. Li JD, et al. Among authors: nadel ja. Proc Natl Acad Sci U S A. 1997 Feb 4;94(3):967-72. doi: 10.1073/pnas.94.3.967. Proc Natl Acad Sci U S A. 1997. PMID: 9023366 Free PMC article.

90

Functional type II VIP-PACAP receptors in human airway epithelial-like cells.

Lindén A, Yoshihara S, Cardell LO, Kaneko T, Stjärne P, Nadel JA. Lindén A, et al. Among authors: nadel ja. Peptides. 1997;18(6):843-6. doi: 10.1016/s0196-9781(97)00017-x. Peptides. 1997. PMID: 9285933

91

A novel PACAP 1-27 analogue causes sustained smooth muscle relaxation in guinea-pig trachea.

Yoshihara S, Lindén A, Kashimoto K, Nagano Y, Ichimura T, Nadel JA. Yoshihara S, et al. Among authors: nadel ja. Ann N Y Acad Sci. 1996 Dec 26;805:536-42. doi: 10.1111/j.1749-6632.1996.tb17515.x. Ann N Y Acad Sci. 1996. PMID: 8993435 No abstract available.

92

Dimethyl sulfoxide decreases interleukin-8-mediated neutrophil recruitment in the airways.

Massion PP, Lindén A, Inoue H, Mathy M, Grattan KM, Nadel JA. Massion PP, et al. Among authors: nadel ja. Am J Physiol. 1996 Nov;271(5 Pt 1):L838-43. doi: 10.1152/ajplung.1996.271.5.L838. Am J Physiol. 1996. PMID: 8944728

93

Classical second messengers are not involved in proteinase-induced degranulation of airway gland cells.

Sommerhoff CP, Fang KC, Nadel JA, Caughey GH. Sommerhoff CP, et al. Among authors: nadel ja. Am J Physiol. 1996 Nov;271(5 Pt 1):L796-803. doi: 10.1152/ajplung.1996.271.5.L796. Am J Physiol. 1996. PMID: 8944723

94

Randomised double-blind placebo-controlled study of the effect of inhibition of nitric oxide synthesis in bradykinin-induced asthma.

Ricciardolo FL, Geppetti P, Mistretta A, Nadel JA, Sapienza MA, Bellofiore S, Di Maria GU. Ricciardolo FL, et al. Among authors: nadel ja. Lancet. 1996 Aug 10;348(9024):374-7. doi: 10.1016/s0140-6736(96)04450-9. Lancet. 1996. PMID: 8709736 Clinical Trial.

95

Increased liposome extravasation in selected tissues: effect of substance P.

Rosenecker J, Zhang W, Hong K, Lausier J, Geppetti P, Yoshihara S, Papahadjopoulos D, Nadel JA. Rosenecker J, et al. Among authors: nadel ja. Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7236-41. doi: 10.1073/pnas.93.14.7236. Proc Natl Acad Sci U S A. 1996. PMID: 8692975 Free PMC article.

96

NK1 receptor antagonist CP-99,994 inhibits cigarette smoke-induced neutrophil and eosinophil adhesion in rat tracheal venules.

Baluk P, Bertrand C, Geppetti P, McDonald DM, Nadel JA. Baluk P, et al. Among authors: nadel ja. Exp Lung Res. 1996 Jul-Aug;22(4):409-18. doi: 10.3109/01902149609046032. Exp Lung Res. 1996. PMID: 8872085

97

Genetics reveals importance of platelet activating factor in asthma and possibly other inflammatory states.

Nadel JA. Nadel JA. J Clin Invest. 1996 Jun 15;97(12):2689-90. doi: 10.1172/JCI118720. J Clin Invest. 1996. PMID: 8675676 Free PMC article. No abstract available.

98

Tachykinins mediate the potentiation of antigen-induced bronchoconstriction by cold air in guinea pigs.

Yoshihara S, Geppetti P, Lindén A, Hara M, Chan B, Nadel JA. Yoshihara S, et al. Among authors: nadel ja. J Allergy Clin Immunol. 1996 Mar;97(3):756-60. doi: 10.1016/s0091-6749(96)80152-7. J Allergy Clin Immunol. 1996. PMID: 8613631

99

Cold air-induced bronchoconstriction is mediated by tachykinin and kinin release in guinea pigs.

Yoshihara S, Geppetti P, Hara M, Linden A, Ricciardolo FL, Chan B, Nadel JA. Yoshihara S, et al. Among authors: nadel ja. Eur J Pharmacol. 1996 Feb 5;296(3):291-6. doi: 10.1016/0014-2999(95)00719-9. Eur J Pharmacol. 1996. PMID: 8904081

100

Ragweed antigen causes interleukin-8 production in sensitized dog trachea.

Kaneko T, Massion PR, Hara M, Nadel JA. Kaneko T, et al. Among authors: nadel ja. Am J Respir Crit Care Med. 1996 Jan;153(1):136-40. doi: 10.1164/ajrccm.153.1.8542106. Am J Respir Crit Care Med. 1996. PMID: 8542106

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