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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 3
1947 4
1948 3
1949 3
1950 3
1951 11
1952 9
1953 6
1954 12
1955 7
1956 5
1957 14
1958 14
1959 17
1960 19
1961 19
1962 23
1963 46
1964 61
1965 70
1966 180
1967 215
1968 212
1969 198
1970 209
1971 186
1972 199
1973 231
1974 295
1975 368
1976 406
1977 601
1978 981
1979 1192
1980 15684
1981 33526
1982 34550
1983 35010
1984 36719
1985 37422
1986 38594
1987 39962
1988 41076
1989 42717
1990 44827
1991 46114
1992 46701
1993 47433
1994 48920
1995 49309
1996 49492
1997 49828
1998 50824
1999 52351
2000 54914
2001 56285
2002 59354
2003 63571
2004 71238
2005 77893
2006 86487
2007 93069
2008 103157
2009 109956
2010 119287
2011 128385
2012 132922
2013 138081
2014 139468
2015 140574
2016 135808
2017 130854
2018 133132
2019 134150
2020 146464
2021 152941
2022 138274
2023 132948
2024 43557
2025 1

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Derivation and Validation of a Scoring System for Predicting Poor Outcome After Posterior Circulation Ischemic Stroke in China.
Yang J, Lin X, Wang A, Meng X, Zhao X, Jing J, Zhang Y, Li H, Wang Y. Yang J, et al. Neurology. 2024 Jun 11;102(11):e209312. doi: 10.1212/WNL.0000000000209312. Epub 2024 May 17. Neurology. 2024. PMID: 38759139
METHODS: The score was developed from a prospective derivation cohort named the Third China National Stroke Registry (August 2015-March 2018) and validated in a spatiotemporal independent validation cohort (December 2017-March 2023) in China. ...Among them, 384 (11.7%) and …
METHODS: The score was developed from a prospective derivation cohort named the Third China National Stroke Registry (August 2015-Mar …
Prediction of Large Vessel Occlusion Stroke Using Clinical Registries for Research.
de Havenon A, Ayodele I, Alhanti B, Mac Grory B, Xian Y, Fonarow G, Smith EE, Worrall BB. de Havenon A, et al. Neurology. 2024 Jun 11;102(11):e209424. doi: 10.1212/WNL.0000000000209424. Epub 2024 May 17. Neurology. 2024. PMID: 38759133
The area under the receiver operating curve (AUC) for the final model, including age, sex, hypertension, dyslipidemia, atrial fibrillation, diabetes, TOAST stroke mechanism, and NIH Stroke Scale (NIHSS), was 0.79 (95% CI 0.79-0.80). Without TOAST mechanism, the AUC was 0.7 …
The area under the receiver operating curve (AUC) for the final model, including age, sex, hypertension, dyslipidemia, atrial fibrillation, …
Interferon signaling in the nasal epithelium distinguishes among lethal and common cold coronaviruses and mediates viral clearance.
Otter CJ, Renner DM, Fausto A, Tan LH, Cohen NA, Weiss SR. Otter CJ, et al. Proc Natl Acad Sci U S A. 2024 May 21;121(21):e2402540121. doi: 10.1073/pnas.2402540121. Epub 2024 May 17. Proc Natl Acad Sci U S A. 2024. PMID: 38758698
All respiratory viruses establish primary infections in the nasal epithelium, where efficient innate immune induction may prevent dissemination to the lower airway and thus minimize pathogenesis. Human coronaviruses (HCoVs) cause a range of pathologies, but the host and vi …
All respiratory viruses establish primary infections in the nasal epithelium, where efficient innate immune induction may prevent disseminat …
A Systematized Review of Quantitative Ultrasound Based on First-Order Speckle Statistics.
Christensen AM, Rosado-Mendez IM, Hall TJ. Christensen AM, et al. IEEE Trans Ultrason Ferroelectr Freq Control. 2024 May 17;PP. doi: 10.1109/TUFFC.2024.3402560. Online ahead of print. IEEE Trans Ultrason Ferroelectr Freq Control. 2024. PMID: 38758626
A total of 388 articles were collected from a systematic search for first-order speckle statistics in diagnostic ultrasound in the NIH PubMed database and Elsevier's Scopus database. Articles were grouped by basic characteristics and evaluated for addressing fundamental as …
A total of 388 articles were collected from a systematic search for first-order speckle statistics in diagnostic ultrasound in the NIH …
High prevalence of hepatitis C virus infection among incarcerated persons: Results from the Louisiana Hepatitis C Elimination Plan's opt-out testing program in prisons.
Irvin R, Landry G, Jones MR, James A, Schexnayder J, Rodriguez S, Wendell D, Barthe K, Britton E, LeSar K, Manogue S, Sugarman OK, Brown C, Burgess S, Mehta SH, Thomas DL, Robinson W; Louisiana Hepatitis C Elimination Plan Team. Irvin R, et al. J Viral Hepat. 2024 May 17. doi: 10.1111/jvh.13941. Online ahead of print. J Viral Hepat. 2024. PMID: 38758571
In the United States, modelling studies suggest a high prevalence of hepatitis C virus (HCV) infection in incarcerated populations. ...To the extent that Louisiana is representative, to eliminate HCV in the United States, it will be important for incar …
In the United States, modelling studies suggest a high prevalence of hepatitis C virus (HCV) infection in incarcerated populat …
Inherited CARD9 Deficiency Due to a Founder Effect in East Asia.
Tomomasa D, Lee BH, Hirata Y, Inoue Y, Majima H, Imanaka Y, Asano T, Katakami T, Lee J, Hijikata A, Worakitchanon W, Yang X, Wang X, Watanabe A, Kamei K, Kageyama Y, Seo GH, Fujimoto A, Casanova JL, Puel A, Morio T, Okada S, Kanegane H. Tomomasa D, et al. J Clin Immunol. 2024 May 17;44(5):121. doi: 10.1007/s10875-024-01724-7. J Clin Immunol. 2024. PMID: 38758287
Genome-wide loss of heterozygosity predicts aggressive, treatment-refractory behavior in pituitary neuroendocrine tumors.
Lin AL, Rudneva VA, Richards AL, Zhang Y, Woo HJ, Cohen M, Tisnado J, Majd N, Wardlaw SL, Page-Wilson G, Sengupta S, Chow F, Goichot B, Ozer BH, Dietrich J, Nachtigall L, Desai A, Alano T, Ogilive S, Solit DB, Bale TA, Rosenblum M, Donoghue MTA, Geer EB, Tabar V. Lin AL, et al. Acta Neuropathol. 2024 May 17;147(1):85. doi: 10.1007/s00401-024-02736-8. Acta Neuropathol. 2024. PMID: 38758238
Adverse Event Following Immunization Monitoring System in Japan.
Okuyama M, Kamiya H, Kamidani S, Saitoh A. Okuyama M, et al. Pediatr Infect Dis J. 2024 Feb 1;43(2):e52-e56. doi: 10.1097/INF.0000000000004184. Epub 2023 Dec 27. Pediatr Infect Dis J. 2024. PMID: 38758206 Review.
Although immunization is essential for maintaining public health, adverse events following immunization (AEFI) occur at a certain rate. ...
Although immunization is essential for maintaining public health, adverse events following immunization (AEFI) occur at a certain rat …
Tenofovir, emtricitabine, lamivudine and dolutegravir concentrations in plasma and urine following drug intake cessation in a randomized controlled directly observed pharmacokinetic trial to aid point-of-care testing.
Else LJ, Dickinson L, Edick S, Zyhowski A, Ho K, Meyn L, Dilly-Penchala S, Thompson B, Shaw V, Khoo S, Brand RM. Else LJ, et al. J Antimicrob Chemother. 2024 May 17:dkae147. doi: 10.1093/jac/dkae147. Online ahead of print. J Antimicrob Chemother. 2024. PMID: 38758205
BACKGROUND: Poor adherence to ART and pre-exposure prophylaxis (PrEP) can impact patient and public health. Point-of-care testing (POCT) may aid monitoring and adherence interventions. ...
BACKGROUND: Poor adherence to ART and pre-exposure prophylaxis (PrEP) can impact patient and public health. Point-of-care testing (PO …
Guidelines for Assessing Maternal Cardiovascular Physiology During Pregnancy and Postpartum.
Collins HE, Alexander BT, Care AS, Davenport MH, Davidge ST, Eghbali M, Giussani DA, Hoes MF, Julian CG, LaVoie HA, Olfert IM, Ozanne SE, Bytautiene Prewit E, Warrington JP, Zhang L, Goulopoulou S. Collins HE, et al. Am J Physiol Heart Circ Physiol. 2024 May 17. doi: 10.1152/ajpheart.00055.2024. Online ahead of print. Am J Physiol Heart Circ Physiol. 2024. PMID: 38758127 Review.
Therefore, these guidelines aim to provide information regarding best practices and recommendations to accurately and rigorously measure cardiovascular physiology during normal and cardiovascular-disease-complicated pregnancies in human and animal models....
Therefore, these guidelines aim to provide information regarding best practices and recommendations to accurately and rigorously measure car …
Response to Letter to the Editor.
Bauer SR, Langston ME, Ferrucci L, Simonsick EM. Bauer SR, et al. J Gerontol A Biol Sci Med Sci. 2024 Jun 1;79(6):glae103. doi: 10.1093/gerona/glae103. J Gerontol A Biol Sci Med Sci. 2024. PMID: 38758044 No abstract available.
Putting science to work for women's health.
Clayton JA, D'Souza RN. Clayton JA, et al. J Dent Educ. 2024 Apr;88 Suppl 1:708-712. doi: 10.1002/jdd.13566. J Dent Educ. 2024. PMID: 38758039
The initiative fosters interdisciplinary collaboration, supporting research on autoimmune diseases, menopause, oral health, and chronic pain conditions. ORWH serves as the focal point for National Institutes of Health (NIH) women's health …
The initiative fosters interdisciplinary collaboration, supporting research on autoimmune diseases, menopause, oral health, and chron …
Predicting aggressive behaviors: Examining unique and interactive roles of PTSD and emotion dysregulation in a minority sample.
Hatfield O, Bresin K, Mekawi Y, Michopoulos V, Fani N, Bradley B, Powers A. Hatfield O, et al. Aggress Behav. 2024 May;50(3):e22149. doi: 10.1002/ab.22149. Aggress Behav. 2024. PMID: 38757986
Aggression is a costly public health problem with severe and multi-faceted negative consequences and thus, identifying factors that contribute to aggression, particularly in understudied populations, is necessary to develop more effective interventions to reduce the public …
Aggression is a costly public health problem with severe and multi-faceted negative consequences and thus, identifying factors that c …
The whole genome sequence of Polish vaccine strain Mycobacterium bovis BCG Moreau.
Krysztopa-Grzybowska K, Lach J, Polak M, Strapagiel D, Dziadek J, Olszewski M, Zasada AA, Darlińska A, Lutyńska A, Augustynowicz-Kopeć E. Krysztopa-Grzybowska K, et al. Microbiol Spectr. 2024 May 17:e0425923. doi: 10.1128/spectrum.04259-23. Online ahead of print. Microbiol Spectr. 2024. PMID: 38757975
Generalizing Diffusion Tensor Imaging of the Physis and Metaphysis.
Luo KL, Santos L, Tokaria R, Jambawilakar S, Duong PT, Raya JG, Mostoufi-Moab S, Jaramillo D. Luo KL, et al. J Magn Reson Imaging. 2024 May 17. doi: 10.1002/jmri.29455. Online ahead of print. J Magn Reson Imaging. 2024. PMID: 38757966
Microhomology-mediated repair machinery and its relationship with HPV-mediated oncogenesis.
Chatterjee S, Starrett GJ. Chatterjee S, et al. J Med Virol. 2024 May;96(5):e29674. doi: 10.1002/jmv.29674. J Med Virol. 2024. PMID: 38757834 Review.
Human Papillomaviruses (HPV) are a diverse family of non-enveloped dsDNA viruses that infect the skin and mucosal epithelia. ...
Human Papillomaviruses (HPV) are a diverse family of non-enveloped dsDNA viruses that infect the skin and mucosal epithelia. ...
Editorial: Has MetALD met the presumption? Authors' reply.
Tamaki N, Kimura T, Wakabayashi SI, Umemura T, Izumi N, Loomba R, Kurosaki M. Tamaki N, et al. Aliment Pharmacol Ther. 2024 May 17. doi: 10.1111/apt.18047. Online ahead of print. Aliment Pharmacol Ther. 2024. PMID: 38757828 No abstract available.
Biotin labeling allows for post-transfusion functional assessment of stored human platelets in mice.
Bailey SL, Bochenek M, Chauhan A, Miller B, Stolla M. Bailey SL, et al. Transfusion. 2024 May 17. doi: 10.1111/trf.17879. Online ahead of print. Transfusion. 2024. PMID: 38757806
BACKGROUND: Platelet radiolabeling with radioisotopes is currently used for human platelet recovery and survival studies. Biotinylation enables ex vivo post-transfusion platelet function testing. ...
BACKGROUND: Platelet radiolabeling with radioisotopes is currently used for human platelet recovery and survival studies. Biotinylati …
Incident heart failure in chronic kidney disease: proteomics informs biology and risk stratification.
Dubin RF, Deo R, Ren Y, Wang J, Pico AR, Mychaleckyj JC, Kozlitina J, Arthur V, Lee H, Shah A, Feldman H, Bansal N, Zelnick L, Rao P, Sukul N, Raj DS, Mehta R, Rosas SE, Bhat Z, Weir MR, He J, Chen J, Kansal M, Kimmel PL, Ramachandran VS, Waikar SS, Segal MR, Ganz P; CRIC Study Investigators. Dubin RF, et al. Eur Heart J. 2024 May 17:ehae288. doi: 10.1093/eurheartj/ehae288. Online ahead of print. Eur Heart J. 2024. PMID: 38757788
BACKGROUND AND AIMS: Incident heart failure (HF) among individuals with chronic kidney disease (CKD) incurs hospitalizations that burden patients and health care systems. There are few preventative therapies, and the Pooled Cohort equations to Prevent Heart Failure (PCP-HF …
BACKGROUND AND AIMS: Incident heart failure (HF) among individuals with chronic kidney disease (CKD) incurs hospitalizations that burden pat …
Safety and clinical outcomes of endovascular therapy versus medical management in late presentation of large ischemic stroke.
Mujanovic A, Strbian D, Demeestere J, Marto JP, Puetz V, Nogueira RG, Abdalkader M, Nagel S, Raymond J, Ribo M, Michel P, Yoshimura S, Zaidat OO, Winzer S, Ortega-Gutierrez S, Sheth SA, Siegler JE, Dusart A, Haussen DC, Henon H, Serrallach BL, Mohammaden MH, Möhlenbruch MA, Olive-Gadea M, Puri AS, Sakai N, Klein P, Tomppo L, Caparros F, Ramos JN, Jumaa M, Zaidi S, Dobrocky T, Martinez-Majander N, Nannoni S, Bellante F, Rodriguez-Calienes A, Salazar-Marioni S, Virtanen P, Kaiser DP, Ventura R, Jesser J, Castonguay AC, Qureshi MM, Masoud HE, Galecio-Castillo M, Requena M, Lauha R, Hu W, Lin E, Miao Z, Roy D, Yamagami H, Seiffge DJ, Strambo D, Ringleb PA, Lemmens R, Fischer U, Nguyen TN, Kaesmacher J. Mujanovic A, et al. Eur Stroke J. 2024 May 17:23969873241249406. doi: 10.1177/23969873241249406. Online ahead of print. Eur Stroke J. 2024. PMID: 38757713
FMRP regulates postnatal neuronal migration via MAP1B.
Messaoudi S, Allam A, Stoufflet J, Paillard T, Le Ven A, Fouquet C, Doulazmi M, Trembleau A, Caille I. Messaoudi S, et al. Elife. 2024 May 17;12:RP88782. doi: 10.7554/eLife.88782. Elife. 2024. PMID: 38757694
Lineage-Specific Mesenchymal Stromal Cells Derived from Human iPSCs Showed Distinct Patterns in Transcriptomic Profile and Extracellular Vesicle Production.
Winston T, Song Y, Shi H, Yang J, Alsudais M, Kontaridis MI, Wu Y, Gaborski TR, Meng Q, Cooney RN, Ma Z. Winston T, et al. Adv Sci (Weinh). 2024 May 17:e2308975. doi: 10.1002/advs.202308975. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 38757640
Over the past decades, mesenchymal stromal cells (MSCs) have been extensively investigated as a potential therapeutic cell source for the treatment of various disorders. Differentiation of MSCs from human induced pluripotent stem cells (iMSCs) has provided a scalable appro …
Over the past decades, mesenchymal stromal cells (MSCs) have been extensively investigated as a potential therapeutic cell source for the tr …
Prevalence of thyroid nodules in residents of Ukraine exposed as children or adolescents to iodine-131 from the Chornobyl accident.
Cahoon EK, Grimm E, Mabuchi K, Mai JZ, Zhang R, Drozdovitch V, Hatch M, Little MP, Peters KO, Bogdanova TI, Shelkovoy E, Shpak VM, Terekhova G, Zamotayeva G, Pasteur IP, Masiuk SV, Chepurny M, Zablotska LB, McConnell R, O'Kane P, Tronko MD, Brenner AV. Cahoon EK, et al. Thyroid. 2024 May 17. doi: 10.1089/thy.2023.0654. Online ahead of print. Thyroid. 2024. PMID: 38757581
DexDesign: an OSPREY-based algorithm for designing de novo D-peptide inhibitors.
Guerin N, Childs H, Zhou P, Donald BR. Guerin N, et al. Protein Eng Des Sel. 2024 Jan 29;37:gzae007. doi: 10.1093/protein/gzae007. Protein Eng Des Sel. 2024. PMID: 38757573
With over 270 unique occurrences in the human genome, peptide-recognizing PDZ domains play a central role in modulating polarization, signaling, and trafficking pathways. ...
With over 270 unique occurrences in the human genome, peptide-recognizing PDZ domains play a central role in modulating polarization, …
Toxoplasma replication is inhibited by MMV676477 without development of resistance.
Abbaali I, Truong D, Wetzel DM, Morrissette NS. Abbaali I, et al. Cytoskeleton (Hoboken). 2024 May 16. doi: 10.1002/cm.21876. Online ahead of print. Cytoskeleton (Hoboken). 2024. PMID: 38757481
In this report, we show that MMV676477 inhibits intracellular growth of the human apicomplexan pathogen Toxoplasma gondii with an EC(50) value of ~50 nM. MMV676477 does not stabilize vertebrate microtubules or cause other toxic effects in human fibroblasts. The avai …
In this report, we show that MMV676477 inhibits intracellular growth of the human apicomplexan pathogen Toxoplasma gondii with an EC( …
Enhancing sleep health in urban American Indian/Alaska Native adolescents: Implications for culturally tailored interventions.
Dong L, Brown RA, Palimaru AI, D'Amico EJ, Dickerson DL, Klein DJ, Johnson CL, Troxel WM. Dong L, et al. J Adolesc. 2024 May 16. doi: 10.1002/jad.12350. Online ahead of print. J Adolesc. 2024. PMID: 38757459
BACKGROUND: Urban American Indian/Alaska Native (AI/AN) adolescents are vulnerable to sleep and other health-related disparities due to numerous social drivers, including historical trauma and relocation to urban areas. ...Parental involvement in sleep routines vari …
BACKGROUND: Urban American Indian/Alaska Native (AI/AN) adolescents are vulnerable to sleep and other health-related disparities due …
Serum ferritin and risk of colonic neoplasia: Implications for the workup and treatment of iron deficiency.
Urback AL, Martens K, McMurry HS, Sharma A, Citti C, DeLoughery TG, Shatzel JJ. Urback AL, et al. Eur J Haematol. 2024 May 16. doi: 10.1111/ejh.14229. Online ahead of print. Eur J Haematol. 2024. PMID: 38757452 Review.
As the incidence of early-onset CRC (age <50 years) rises in the United States, there is an increasing need to identify risk predictors to aid in the early detection of CRC. ...
As the incidence of early-onset CRC (age <50 years) rises in the United States, there is an increasing need to identify ris …
Familial communication and cascade testing following elective genomic testing.
Adelson SM, Blout Zawatsky CL, Hickingbotham MR, Bell ME, Platt DM, Leonhard JR, Zoltick ES, Hajek CA, Green RC, Christensen KD. Adelson SM, et al. J Genet Couns. 2024 May 16. doi: 10.1002/jgc4.1907. Online ahead of print. J Genet Couns. 2024. PMID: 38757439
Familial communication of results and cascade genetic testing (CGT) can extend the benefits of genetic screening beyond the patient to their at-risk relatives. While an increasing number of health systems are offering genetic screening as an elective clinical service, data …
Familial communication of results and cascade genetic testing (CGT) can extend the benefits of genetic screening beyond the patient to their …
Implications of trial eligibility in patients with heart failure with mildly reduced or preserved ejection fraction.
Peters AE, Clare RM, Chiswell K, Harrington J, Kelsey A, Hernandez A, Felker GM, Mentz RJ, DeVore AD. Peters AE, et al. ESC Heart Fail. 2024 May 16. doi: 10.1002/ehf2.14777. Online ahead of print. ESC Heart Fail. 2024. PMID: 38757437
METHODS AND RESULTS: Patients with HFmrEF/HFpEF from a large US healthcare system were identified through a computable phenotype applied in linked imaging and electronic health record databases. We evaluated shared eligibility criteria from five recent/ongoing HFmrEF/HFpEF …
METHODS AND RESULTS: Patients with HFmrEF/HFpEF from a large US healthcare system were identified through a computable phenotype applied in …
Associations between middle childhood executive control aspects and adolescent substance use and externalizing and internalizing problems.
Mason WA, Fleming CB, Patwardhan I, Guo Y, James TD, Nelson JM, Espy KA, Nelson TD. Mason WA, et al. J Res Adolesc. 2024 May 16. doi: 10.1111/jora.12943. Online ahead of print. J Res Adolesc. 2024. PMID: 38757393
Participants were 301 children (ages 3-6 years; 48.2% male) recruited from a Midwestern city in the United States and followed into adolescence (ages 14-18 years). Working memory had a statistically significant unadjusted association with externalizing problems (r = …
Participants were 301 children (ages 3-6 years; 48.2% male) recruited from a Midwestern city in the United States and followed …
Heat-induced structural and chemical changes to a computationally designed miniprotein.
Dudley JA, Park S, Cho O, Wells NGM, MacDonald ME, Blejec KM, Fetene E, Zanderigo E, Houliston S, Liddle JC, Dashnaw CM, Sabo TM, Shaw BF, Balsbaugh JL, Rocklin GJ, Smith CA. Dudley JA, et al. Protein Sci. 2024 Jun;33(6):e4991. doi: 10.1002/pro.4991. Protein Sci. 2024. PMID: 38757381
Our analysis reveals important principles for future miniprotein designs and the potential for high stability to result in long-lived alternate conformational states....
Our analysis reveals important principles for future miniprotein designs and the potential for high stability to result in long-lived altern …
Insights on the G protein-coupled receptor helix 8 solution structure and orientation using a neurotensin receptor 1 peptide.
Bower JB, Robson SA, Ziarek JJ. Bower JB, et al. Protein Sci. 2024 Jun;33(6):e4976. doi: 10.1002/pro.4976. Protein Sci. 2024. PMID: 38757374
G-protein coupled receptors (GPCRs) are the largest class of membrane proteins encoded in the human genome with high pharmaceutical relevance and implications to human health. ...
G-protein coupled receptors (GPCRs) are the largest class of membrane proteins encoded in the human genome with high pharmaceutical r …
Using natural language processing in emergency medicine health service research: A systematic review and meta-analysis.
Wang H, Alanis N, Haygood L, Swoboda TK, Hoot N, Phillips D, Knowles H, Stinson SA, Mehta P, Sambamoorthi U. Wang H, et al. Acad Emerg Med. 2024 May 16. doi: 10.1111/acem.14937. Online ahead of print. Acad Emerg Med. 2024. PMID: 38757352 Review.
Consequently, we advocate for the adoption of NLP-based research to augment EM health care management....
Consequently, we advocate for the adoption of NLP-based research to augment EM health care management....
Chinese Immigrant Caregivers: Understanding Their Unmet Needs and the Co-Design of an mHealth App.
Yu K, Jiang H, Liu M, Wu S, Jordan-Marsh M, Chi I. Yu K, et al. Can J Aging. 2024 May 17:1-8. doi: 10.1017/S0714980824000187. Online ahead of print. Can J Aging. 2024. PMID: 38757195
Mobile technology-facilitated interventions can promote caregiver health by providing easy access to self-care materials. OBJECTIVE: This study employed a design thinking framework to examine Chinese immigrant caregivers' (CICs) unmet self-care needs and co-design an app f …
Mobile technology-facilitated interventions can promote caregiver health by providing easy access to self-care materials. OBJECTIVE: …
Modification of MgH2 hydrogen storage performance by nickel-based composite catalyst Ni/NiO.
Li W, Yang X, Hou Q, Lu X, Kong J, Su J. Li W, et al. Heliyon. 2024 May 4;10(9):e30688. doi: 10.1016/j.heliyon.2024.e30688. eCollection 2024 May 15. Heliyon. 2024. PMID: 38756560 Free PMC article.
During the dehydrogenation/rehydrogenation cycle, Mg(2)Ni/Mg(2)NiH(4) could promote hydrogen diffusion, thus enhancing the hydrogen storage performance of Mg/MgH(2)....
During the dehydrogenation/rehydrogenation cycle, Mg(2)Ni/Mg(2)NiH(4) could promote hydrogen diffusion, thus enhancing the hydrogen s …
Gonadotropin-Releasing Hormone (GnRH) Agonists Do Not Protect Ovarian Function in Patients Undergoing Stem Cell Transplants.
Benor A, Decherney A. Benor A, et al. Cureus. 2024 Apr 16;16(4):e58387. doi: 10.7759/cureus.58387. eCollection 2024 Apr. Cureus. 2024. PMID: 38756303 Free PMC article.
We explored the use of leuprolide (a type of GnRH-a) in preventing primary ovarian insufficiency (POI) in a cohort study of patients who underwent hematopoietic stem cell transplants (HSCT) at the National Institutes of Health (NIH); since the conditio …
We explored the use of leuprolide (a type of GnRH-a) in preventing primary ovarian insufficiency (POI) in a cohort study of patients who und …
The most fundamental and popular literature on functional near-infrared spectroscopy: a bibliometric analysis of the top 100 most cited articles.
Li J, Li Y, Huang M, Li D, Wan T, Sun F, Zeng Q, Xu F, Wang J. Li J, et al. Front Neurol. 2024 May 2;15:1388306. doi: 10.3389/fneur.2024.1388306. eCollection 2024. Front Neurol. 2024. PMID: 38756218 Free PMC article.
Harvard University (n = 22) conducted most cited articles. The United States, Germany, Japan, and the United Kingdom had most cited articles, respectively. The most common keywords were near-infrared spectroscopy, activation, cerebral-blood-flow, brain, newbo …
Harvard University (n = 22) conducted most cited articles. The United States, Germany, Japan, and the United Kingdom ha …
Effectiveness of artificial intelligence vs. human coaching in diabetes prevention: a study protocol for a randomized controlled trial.
Abusamaan MS, Ballreich J, Dobs A, Kane B, Maruthur N, McGready J, Riekert K, Wanigatunga AA, Alderfer M, Alver D, Lalani B, Ringham B, Vandi F, Zade D, Mathioudakis NN. Abusamaan MS, et al. Trials. 2024 May 16;25(1):325. doi: 10.1186/s13063-024-08177-8. Trials. 2024. PMID: 38755706
Participants include adults aged 18-75 years with laboratory confirmed prediabetes, a BMI of 25 kg/m(2) ( 23 kg/m(2) for Asians), English proficiency, and smartphone users. This U.S. study is conducted at Johns Hopkins Medicine in Baltimore, MD, and Reading Hospital …
Participants include adults aged 18-75 years with laboratory confirmed prediabetes, a BMI of 25 kg/m(2) ( 23 kg/m(2) for Asians), English pr …
RECOVER-NEURO: study protocol for a multi-center, multi-arm, phase 2, randomized, active comparator trial evaluating three interventions for cognitive dysfunction in post-acute sequelae of SARS-CoV-2 infection (PASC).
Knopman DS, Laskowitz DT, Koltai DC, Charvet LE, Becker JH, Federman AD, Wisnivesky J, Mahncke H, Van Vleet TM, Bateman L, Kim DY, O'Steen A, James M, Silverstein A, Lokhnygina Y, Rich J, Feger BJ, Zimmerman KO. Knopman DS, et al. Trials. 2024 May 17;25(1):326. doi: 10.1186/s13063-024-08156-z. Trials. 2024. PMID: 38755688
Accommodating detection limits of multiple exposures in environmental mixture analyses: an overview of statistical approaches.
Lee M, Saha A, Sundaram R, Albert PS, Zhao S. Lee M, et al. Environ Health. 2024 May 16;23(1):48. doi: 10.1186/s12940-024-01088-w. Environ Health. 2024. PMID: 38755683
BACKGROUND: Identifying the impact of environmental mixtures on human health is an important topic. However, such studies face challenges when exposure measurements lie below limit of detection (LOD). ...We further analyzed data from the National Health …
BACKGROUND: Identifying the impact of environmental mixtures on human health is an important topic. However, such studies face …
BarlowTwins-CXR: enhancing chest X-ray abnormality localization in heterogeneous data with cross-domain self-supervised learning.
Sheng H, Ma L, Samson JF, Liu D. Sheng H, et al. BMC Med Inform Decis Mak. 2024 May 16;24(1):126. doi: 10.1186/s12911-024-02529-9. BMC Med Inform Decis Mak. 2024. PMID: 38755563
Initially, self-supervised pre-training was performed using an adjusted Barlow Twins algorithm on the NIH dataset with a Resnet50 backbone pre-trained on ImageNet. This was followed by supervised fine-tuning on the VinDr-CXR dataset using Faster R-CNN with Feature Pyramid …
Initially, self-supervised pre-training was performed using an adjusted Barlow Twins algorithm on the NIH dataset with a Resnet50 bac …
Trends in Use and Evidence of Adherence to Risk Evaluation and Mitigation Strategy Pregnancy Testing Requirements for Thalidomide, Lenalidomide, and Pomalidomide in the USA, 2000-2020.
Mahesri M, Sarpatwari A, Huybrechts KF, Lii J, Lee SB, Toyserkani GA, LaCivita C, Zhou EH, Pan GJD, Kesselheim AS, Bykov K. Mahesri M, et al. Drug Saf. 2024 May 16. doi: 10.1007/s40264-024-01443-3. Online ahead of print. Drug Saf. 2024. PMID: 38755509
OBJECTIVE: We evaluated dispensing trends of lenalidomide, pomalidomide, and thalidomide and assessed adherence to REMS pregnancy testing requirements among at-risk patients taking these drugs. METHODS: Using three US health insurance claims databases (Optum Clinformatics …
OBJECTIVE: We evaluated dispensing trends of lenalidomide, pomalidomide, and thalidomide and assessed adherence to REMS pregnancy testing re …
Quantification of healthspan in aging mice: introducing FAMY and GRAIL.
Lamming DW. Lamming DW. Geroscience. 2024 May 17. doi: 10.1007/s11357-024-01200-5. Online ahead of print. Geroscience. 2024. PMID: 38755467
Both metrics are conceptually similar to quality-adjusted life years (QALY), a widely utilized measure of disease burden in humans, and can be readily calculated from data acquired during longitudinal and cross-sectional studies of mouse aging. We find that interventions generall …
Both metrics are conceptually similar to quality-adjusted life years (QALY), a widely utilized measure of disease burden in humans, and can …
Indexing and searching petabase-scale nucleotide resources.
Shiryev SA, Agarwala R. Shiryev SA, et al. Nat Methods. 2024 May 16. doi: 10.1038/s41592-024-02280-z. Online ahead of print. Nat Methods. 2024. PMID: 38755321
The web service of Pebblescout can be reached at https://pebblescout.ncbi.nlm.nih.gov . We show that for a wide range of query lengths, Pebblescout provides a data-driven way for finding relevant subsets of large nucleotide resources, reducing the effort for downstream ana …
The web service of Pebblescout can be reached at https://pebblescout.ncbi.nlm.nih.gov . We show that for a wide range of query length …
Early-stage lung cancer is driven by a transitional cell state dependent on a KRAS-ITGA3-SRC axis.
Moye AL, Dost AF, Ietswaart R, Sengupta S, Ya V, Aluya C, Fahey CG, Louie SM, Paschini M, Kim CF. Moye AL, et al. EMBO J. 2024 May 16. doi: 10.1038/s44318-024-00113-5. Online ahead of print. EMBO J. 2024. PMID: 38755258
The injury state in AT2(KRAS) cells of patients, mice, and organoids was distinguishable from AT2(WT) states via altered receptor expression, including co-expression of ITGA3 and SRC. ...
The injury state in AT2(KRAS) cells of patients, mice, and organoids was distinguishable from AT2(WT) states via altered receptor exp …
Sustained attention operates via dissociable neural mechanisms across different eccentric locations.
Phangwiwat T, Phunchongharn P, Wongsawat Y, Chatnuntawech I, Wang S, Chunharas C, Sprague TC, Woodman GF, Itthipuripat S. Phangwiwat T, et al. Sci Rep. 2024 May 16;14(1):11188. doi: 10.1038/s41598-024-61171-7. Sci Rep. 2024. PMID: 38755251
We tested these alternative accounts by examining the effects of selective attention on the steady-state visually evoked potential (SSVEP) and the fronto-parietal signal measured via EEG from human subjects performing a sustained visuospatial attention task. ...These data …
We tested these alternative accounts by examining the effects of selective attention on the steady-state visually evoked potential (SSVEP) a …
ADAM9 promotes type I interferon-mediated innate immunity during encephalomyocarditis virus infection.
Bazzone LE, Zhu J, King M, Liu G, Guo Z, MacKay CR, Kyawe PP, Qaisar N, Rojas-Quintero J, Owen CA, Brass AL, McDougall W, Baer CE, Cashman T, Trivedi CM, Gack MU, Finberg RW, Kurt-Jones EA. Bazzone LE, et al. Nat Commun. 2024 May 16;15(1):4153. doi: 10.1038/s41467-024-48524-6. Nat Commun. 2024. PMID: 38755212
We previously identified A Disintegrin And Metalloproteinase domain 9 (ADAM9) as an important factor in viral pathogenesis. ADAM9 is implicated in a range of human diseases, including inflammatory diseases; however, its role in viral infection is unknown. ...
We previously identified A Disintegrin And Metalloproteinase domain 9 (ADAM9) as an important factor in viral pathogenesis. ADAM9 is implica …
Impacts of human mobility on the citywide transmission dynamics of 18 respiratory viruses in pre- and post-COVID-19 pandemic years.
Perofsky AC, Hansen CL, Burstein R, Boyle S, Prentice R, Marshall C, Reinhart D, Capodanno B, Truong M, Schwabe-Fry K, Kuchta K, Pfau B, Acker Z, Lee J, Sibley TR, McDermot E, Rodriguez-Salas L, Stone J, Gamboa L, Han PD, Adler A, Waghmare A, Jackson ML, Famulare M, Shendure J, Bedford T, Chu HY, Englund JA, Starita LM, Viboud C. Perofsky AC, et al. Nat Commun. 2024 May 16;15(1):4164. doi: 10.1038/s41467-024-48528-2. Nat Commun. 2024. PMID: 38755171
Bone marrow stromal cells induce chromatin remodeling in multiple myeloma cells leading to transcriptional changes.
Binder M, Szalat RE, Talluri S, Fulciniti M, Avet-Loiseau H, Parmigiani G, Samur MK, Munshi NC. Binder M, et al. Nat Commun. 2024 May 16;15(1):4139. doi: 10.1038/s41467-024-47793-5. Nat Commun. 2024. PMID: 38755155
Here, we show that the interaction between bone marrow stromal cells and myeloma cells (using human cell lines) induces chromatin remodeling of cis-regulatory elements and is associated with changes in the expression of genes involved in the cell migration and cytokine sig …
Here, we show that the interaction between bone marrow stromal cells and myeloma cells (using human cell lines) induces chromatin rem …
TDP-43 proteinopathy in ALS is triggered by loss of ASRGL1 and associated with HML-2 expression.
Garcia-Montojo M, Fathi S, Rastegar C, Simula ER, Doucet-O'Hare T, Cheng YHH, Abrams RPM, Pasternack N, Malik N, Bachani M, Disanza B, Maric D, Lee MH, Wang H, Santamaria U, Li W, Sampson K, Lorenzo JR, Sanchez IE, Mezghrani A, Li Y, Sechi LA, Pineda S, Heiman M, Kellis M, Steiner J, Nath A. Garcia-Montojo M, et al. Nat Commun. 2024 May 16;15(1):4163. doi: 10.1038/s41467-024-48488-7. Nat Commun. 2024. PMID: 38755145
Asparaginase-like-1 protein (ASRGL1) cleaves isoaspartates, which alter protein folding and susceptibility to proteolysis. ASRGL1 gene harbors a copy of the human endogenous retrovirus HML-2, whose overexpression contributes to ALS pathogenesis. ...
Asparaginase-like-1 protein (ASRGL1) cleaves isoaspartates, which alter protein folding and susceptibility to proteolysis. ASRGL1 gene harbo …
Cognitive rehabilitation effects on grey matter volume and Go-NoGo activity in progressive multiple sclerosis: results from the CogEx trial.
Rocca MA, Valsasina P, Romanò F, Tedone N, Amato MP, Brichetto G, Boccia VD, Chataway J, Chiaravalloti ND, Cutter G, Dalgas U, DeLuca J, Farrell RA, Feys P, Freeman J, Inglese M, Meza C, Motl RW, Salter A, Sandroff BM, Feinstein A, Filippi M; Cogex Research Team. Rocca MA, et al. J Neurol Neurosurg Psychiatry. 2024 May 16:jnnp-2024-333460. doi: 10.1136/jnnp-2024-333460. Online ahead of print. J Neurol Neurosurg Psychiatry. 2024. PMID: 38754979
Preclinical development of humanized monoclonal antibodies against CD169 as a broad antiviral therapeutic strategy.
Resa-Infante P, Erkizia I, Muñiz-Trabudua X, Linty F, Bentlage AEH, Perez-Zsolt D, Muñoz-Basagoiti J, Raïch-Regué D, Izquierdo-Useros N, Rispens T, Vidarsson G, Martinez-Picado J. Resa-Infante P, et al. Biomed Pharmacother. 2024 May 15;175:116726. doi: 10.1016/j.biopha.2024.116726. Online ahead of print. Biomed Pharmacother. 2024. PMID: 38754263
Humanized monoclonal antibodies targeting CD169 provide new opportunities in the treatment of infections caused by ganglioside-containing enveloped viruses, which pose a constant threat to human health. In contrast with current neutralizing antibodies that bind anti …
Humanized monoclonal antibodies targeting CD169 provide new opportunities in the treatment of infections caused by ganglioside-containing en …
Development and validation of an episodic memory measure in the Mobile Toolbox (MTB): Arranging Pictures.
Ruth Young S, Dworak EM, Novack MA, Kaat AJ, Adam H, Nowinski CJ, Hosseinian Z, Slotkin J, Stoeger J, Amagai S, Varela Diaz M, Almonte Correa A, Alperin K, Omberg L, Kellen M, Camacho MR, Landavazo B, Nosheny RL, Weiner MW, Gershon R. Ruth Young S, et al. J Clin Exp Neuropsychol. 2024 May 16:1-10. doi: 10.1080/13803395.2024.2353945. Online ahead of print. J Clin Exp Neuropsychol. 2024. PMID: 38753819
INTRODUCTION: Arranging Pictures is a new episodic memory test based on the NIH Toolbox (NIHTB) Picture Sequence Memory measure and optimized for self-administration on a personal smartphone within the Mobile Toolbox (MTB). ...
INTRODUCTION: Arranging Pictures is a new episodic memory test based on the NIH Toolbox (NIHTB) Picture Sequence Memory measure and o …
Low-Dose Aspirin Is the Safest Prophylaxis for Prevention of Venous Thromboembolism After Total Knee Arthroplasty Across All Patient Risk Profiles.
Lavu MS, Porto JR, Hecht CJ 2nd, Acuña AJ, Kaelber DC, Parvizi J, Kamath AF. Lavu MS, et al. J Bone Joint Surg Am. 2024 May 16. doi: 10.2106/JBJS.23.01158. Online ahead of print. J Bone Joint Surg Am. 2024. PMID: 38753809
The present study was designed to characterize the clinical use of various chemoprophylactic agents in patients undergoing TKA and to determine the efficacy of aspirin compared with other agents in patient groups stratified by VTE risk profiles. METHODS: This study utilized a …
The present study was designed to characterize the clinical use of various chemoprophylactic agents in patients undergoing TKA and to determ …
Building on NIH's data sharing policy.
Contaxis N, Badger K, Bohman L, Gonzales S, Kim S, Koshoffer A, Milliken G, Newman J, Otsuji R, Renirie R, Smith K, Urmi U, Yarnell A, Ye H, Yee M. Contaxis N, et al. Science. 2024 May 17;384(6697):747-748. doi: 10.1126/science.adn5594. Epub 2024 May 16. Science. 2024. PMID: 38753788 No abstract available.
Essential role of N-terminal SAM regions in STIM1 multimerization and function.
Sallinger M, Humer C, Ong HL, Narayanasamy S, Lin QT, Fahrner M, Grabmayr H, Berlansky S, Choi S, Schmidt T, Maltan L, Atzgerstorfer L, Niederwieser M, Frischauf I, Romanin C, Stathopulos PB, Ambudkar I, Leitner R, Bonhenry D, Schindl R. Sallinger M, et al. Proc Natl Acad Sci U S A. 2024 May 21;121(21):e2318874121. doi: 10.1073/pnas.2318874121. Epub 2024 May 16. Proc Natl Acad Sci U S A. 2024. PMID: 38753510
Cortico-limbic interactions and carotid atherosclerotic burden during chronic stress exposure.
Gharios C, van Leent MMT, Chang HL, Abohashem S, O'Connor D, Osborne MT, Tang CY, Kaufman AE, Robson PM, Ramachandran S, Calcagno C, Mani V, Trivieri MG, Seligowski AV, Dekel S, Mulder WJM, Murrough JW, Shin LM, Tawakol A, Fayad ZA. Gharios C, et al. Eur Heart J. 2024 May 16:ehae149. doi: 10.1093/eurheartj/ehae149. Online ahead of print. Eur Heart J. 2024. PMID: 38753456
Clustering Identifies Subtypes With Different Phenotypic Characteristics in Women With Polycystic Ovary Syndrome.
van der Ham K, Moolhuijsen LME, Brewer K, Sisk R, Dunaif A, Laven JSE, Louwers YV, Visser JA. van der Ham K, et al. J Clin Endocrinol Metab. 2024 May 16:dgae298. doi: 10.1210/clinem/dgae298. Online ahead of print. J Clin Endocrinol Metab. 2024. PMID: 38753423
In total, 2502 female participants of European ancestry, aged 13 to 45 years with PCOS (according to the Rotterdam criteria), were included. A subset of these (n = 1067) fulfilled the National Institutes of Health criteria (ovulatory dysfunction and hyperandr …
In total, 2502 female participants of European ancestry, aged 13 to 45 years with PCOS (according to the Rotterdam criteria), were included. …
Rural comprehensive cancer care: Qualitative analysis of current challenges and opportunities.
Evans S, Seaman AT, Johnson EC, Engelbart JM, Gao X, Vikas P, Phadke S, Schroeder MC, Lizarraga IM, Charlton ME. Evans S, et al. J Rural Health. 2024 May 16. doi: 10.1111/jrh.12842. Online ahead of print. J Rural Health. 2024. PMID: 38753418
Further research is needed to develop implementation approaches that will extend resources, services, and expertise to rural providers to facilitate high-quality cancer care for all cancer patients....
Further research is needed to develop implementation approaches that will extend resources, services, and expertise to rural provider …
Anti-Asian biases in federal grant reviews: Commentary on Yip et al. (2021).
Yip T, Lorenzo K, Bae J, Hall GN, Cheah CSL, Kiang L, Takeuchi D, Tseng V. Yip T, et al. Am Psychol. 2024 May 16. doi: 10.1037/amp0001337. Online ahead of print. Am Psychol. 2024. PMID: 38753404
Despite comprising over 6% of the U.S. population, less than 1% of the National Institutes of Health's funding portfolio supports science on AANHPI populations. This qualitative study revealed thematic barriers encountered during Natio …
Despite comprising over 6% of the U.S. population, less than 1% of the National Institutes of Health's …
Resource-rational psychopathology.
Bari BA, Gershman SJ. Bari BA, et al. Behav Neurosci. 2024 May 16. doi: 10.1037/bne0000600. Online ahead of print. Behav Neurosci. 2024. PMID: 38753400
Psychopathology is vast and diverse. Across distinct disease states, individuals exhibit symptoms that appear counter to the standard view of rationality (expected utility maximization). ...
Psychopathology is vast and diverse. Across distinct disease states, individuals exhibit symptoms that appear counter to the standard …
Measurement of the self-determination continuum of motivation for engaging in alcohol-related harm reduction behaviors: Improved content coverage of the Treatment Self-Regulation Questionnaire.
Richards DK, Pearson MR; Addictions Research Team. Richards DK, et al. Exp Clin Psychopharmacol. 2024 May 16. doi: 10.1037/pha0000721. Online ahead of print. Exp Clin Psychopharmacol. 2024. PMID: 38753393
Participants (n = 2,236) were college students from psychology departments at 10 universities in eight U.S. states who reported past-month alcohol use and completed the revised TSRQ; the online survey was completed for partial course credit. ...
Participants (n = 2,236) were college students from psychology departments at 10 universities in eight U.S. states who …
Lifespan effects in male UM-HET3 mice treated with sodium thiosulfate, 16-hydroxyestriol, and late-start canagliflozin.
Miller RA, Harrison DE, Cortopassi GA, Dehghan I, Fernandez E, Garratt M, Geisler JG, Ginsburg BC, Han ML, Kaczorowski CC, Kumar N, Leiser SF, Lopez-Cruzan M, Milne G, Mitchell JR, Nelson JF, Reifsnyder PC, Salmon AB, Korstanje R, Rosenthal N, Strong R. Miller RA, et al. Geroscience. 2024 May 16. doi: 10.1007/s11357-024-01176-2. Online ahead of print. Geroscience. 2024. PMID: 38753230
From feulgen to modern methods: marking a century of DNA imaging advances.
Lakadamyali M. Lakadamyali M. Histochem Cell Biol. 2024 May 16. doi: 10.1007/s00418-024-02291-z. Online ahead of print. Histochem Cell Biol. 2024. PMID: 38753186 Review.
The mystery of how human DNA is compactly packaged into a nucleus-a space a hundred thousand times smaller-while still allowing for the regulation of gene function, has long been one of the greatest enigmas in cell biology. ...
The mystery of how human DNA is compactly packaged into a nucleus-a space a hundred thousand times smaller-while still allowing for t …
An endoscopic chisel: intraoperative imaging carves 3D anatomical models.
Mangulabnan JE, Soberanis-Mukul RD, Teufel T, Sahu M, Porras JL, Vedula SS, Ishii M, Hager G, Taylor RH, Unberath M. Mangulabnan JE, et al. Int J Comput Assist Radiol Surg. 2024 May 16. doi: 10.1007/s11548-024-03151-w. Online ahead of print. Int J Comput Assist Radiol Surg. 2024. PMID: 38753135
Biomechanical Analysis of Age-Dependent Changes in Fontan Power Loss.
Sahni A, Marshall L, Cetatoiu MA, Davee J, Schulz N, Eickhoff ER, St Clair N, Ghelani S, Prakash A, Hammer PE, Hoganson DM, Del Nido PJ, Rathod RH, Govindarajan V. Sahni A, et al. Ann Biomed Eng. 2024 May 16. doi: 10.1007/s10439-024-03534-9. Online ahead of print. Ann Biomed Eng. 2024. PMID: 38753109
The Effect of City-Level Sugar-Sweetened Beverage Taxes on Longitudinal HbA1c and Incident Diabetes in Adults With Prediabetes.
Lee C, Sidell MA, Young DR, Hedderson MM, Cohen DA, Liu EF, Barton LJ, Falbe J, Inzhakova G, Sridhar S, Voorhees AC, Han B. Lee C, et al. Diabetes Care. 2024 May 16:dc240228. doi: 10.2337/dc24-0228. Online ahead of print. Diabetes Care. 2024. PMID: 38753006
OBJECTIVE: Prediabetes, which is a condition characterized by higher-than-normal blood glucose levels that are under the threshold for diabetes, impacts over one-third of U.S. adults. Excise taxes on sugar-sweetened beverages (SSBs) are a proposed policy interventio …
OBJECTIVE: Prediabetes, which is a condition characterized by higher-than-normal blood glucose levels that are under the threshold for diabe …
The Polyanalgesic Consensus Conference (PACC)®: Intrathecal Drug Delivery Guidance on Safety and Therapy Optimization When Treating Chronic Noncancer Pain.
Deer TR, Hayek SM, Grider JS, Hagedorn JM, McDowell GC 2nd, Kim P, Dupoiron D, Goel V, Duarte R, Pilitsis JG, Leong MS, De Andrés J, Perruchoud C, Sukumaran H, Abd-Elsayed A, Saulino M, Patin D, Poree LR, Strand N, Gritsenko K, Osborn JA, Dones I, Bux A, Shah JM, Lindsey BL, Shaw E, Yaksh TL, Levy RM. Deer TR, et al. Neuromodulation. 2024 May 13:S1094-7159(24)00066-7. doi: 10.1016/j.neurom.2024.03.003. Online ahead of print. Neuromodulation. 2024. PMID: 38752946 Review.
Section leaders supervised literature searches of MEDLINE, BioMed Central, Current Contents Connect, Embase, International Pharmaceutical Abstracts, Web of Science, Google Scholar, and PubMed from 2017 (when PACC last published guidelines) to the present. Identified studies were …
Section leaders supervised literature searches of MEDLINE, BioMed Central, Current Contents Connect, Embase, International Pharmaceutical Ab …
Effects of Pulsed Radiofrequency Duration in Patients With Chronic Lumbosacral Radicular Pain: A Randomized Double-Blind Study.
Kim CS, Kim Y, Kim DH, Kwon HJ, Shin JW, Choi SS. Kim CS, et al. Neuromodulation. 2024 May 15:S1094-7159(24)00069-2. doi: 10.1016/j.neurom.2024.03.006. Online ahead of print. Neuromodulation. 2024. PMID: 38752945
CLINICAL TRIAL REGISTRATION: The Clinicaltrials.gov registration number under the Clinical Trial Registry of Korea for the study is KCT0003850; https://cris.nih.go.kr....
CLINICAL TRIAL REGISTRATION: The Clinicaltrials.gov registration number under the Clinical Trial Registry of Korea for the study is KCT00038 …
Medical Assistant Health Coaching for Type 2 Diabetes in Primary Care: Results From a Pragmatic Cluster Randomized Controlled Trial.
Fortmann AL, Soriano EC, Gallo LC, Clark TL, Spierling Bagsic SR, Sandoval H, Jones JA, Roesch S, Gilmer T, Schultz J, Bodenheimer T, Philis-Tsimikas A. Fortmann AL, et al. Diabetes Care. 2024 May 16:dc232487. doi: 10.2337/dc23-2487. Online ahead of print. Diabetes Care. 2024. PMID: 38752923
OBJECTIVE: This cluster (clinic-level) randomized controlled trial (RCT) compared medical assistant (MA) health coaching (MAC) with usual care (UC) among at-risk adults with type 2 diabetes in two diverse real-world primary care environments: a federally qualified healt …
OBJECTIVE: This cluster (clinic-level) randomized controlled trial (RCT) compared medical assistant (MA) health coaching (MAC) with u …
Machine Learning Models for Pancreatic Cancer Risk Prediction Using Electronic Health Record Data - A Systematic Review and Assessment.
Mishra AK, Chong B, Arunachalam SP, Oberg AL, Majumder S. Mishra AK, et al. Am J Gastroenterol. 2024 May 16. doi: 10.14309/ajg.0000000000002870. Online ahead of print. Am J Gastroenterol. 2024. PMID: 38752654
We conducted a systematic review to critically evaluate effectiveness of machine learning (ML) and artificial intelligence (AI) techniques applied to Electronic Health Records (EHR) for PC risk prediction. METHODS: Ovid MEDLINE(R), Ovid EMBASE, Ovid Cochrane Central Regist …
We conducted a systematic review to critically evaluate effectiveness of machine learning (ML) and artificial intelligence (AI) techniques a …
Considerations and challenges in support of science and communication of fish consumption advisories for per- and polyfluoroalkyl substances.
Petali JM, Pulster EL, McCarthy C, Pickard HM, Sunderland EM, Bangma J, Carignan CC, Robuck A, Crawford KA, Romano ME, Lohmann R, von Stackelburg K. Petali JM, et al. Integr Environ Assess Manag. 2024 May 16. doi: 10.1002/ieam.4947. Online ahead of print. Integr Environ Assess Manag. 2024. PMID: 38752651 Review.
Federal, state, tribal, or local entities in the United States issue fish consumption advisories (FCAs) as guidance for safer consumption of locally caught fish containing contaminants. ...As a result, several states have derived their own PFAS-related consum …
Federal, state, tribal, or local entities in the United States issue fish consumption advisories (FCAs) as guidance for safer …
Exploring the relationship between school-supervised asthma therapy and social determinants of health in pediatric asthma care.
Al-Halbouni L, Ryan GW, Radu S, Spano M, Sabnani R, Phipatanakul W, Gerald LB, Garg A, Pbert L, Trivedi M. Al-Halbouni L, et al. Pediatr Pulmonol. 2024 May 16. doi: 10.1002/ppul.27065. Online ahead of print. Pediatr Pulmonol. 2024. PMID: 38752604
BACKGROUND: Social determinants of health (SDoH), including access to care, economic stability, neighborhood factors, and social context, strongly influence pediatric asthma outcomes. ...Moreover, our findings underscore the importance of measuring SDoH in th …
BACKGROUND: Social determinants of health (SDoH), including access to care, economic stability, neighborhood factors, and s …
Glial modulators as novel therapeutics for comorbid pain and opioid use disorder.
Schwartz EKC, De Aquino JP, Sofuoglu M. Schwartz EKC, et al. Br J Clin Pharmacol. 2024 May 16. doi: 10.1111/bcp.16094. Online ahead of print. Br J Clin Pharmacol. 2024. PMID: 38752593 Review.
Chronic pain and opioid use disorder (OUD) are major public health problems, with rising opioid-related overdose deaths linked to increased opioid prescriptions for pain management. ...Despite these limitations, these studies yielded positive signals that merit further inv …
Chronic pain and opioid use disorder (OUD) are major public health problems, with rising opioid-related overdose deaths linked to inc …
A longitudinal evaluation of personalized intrinsic network topography and cognitive decline in Parkinson's disease.
Li R, Pozorski V, Dabbs K, Haebig M, Cox CR, Pletcher C, Wey A, Barzgari A, Theisen F, Okonkwo O, Gallagher CL. Li R, et al. Eur J Neurosci. 2024 May 16. doi: 10.1111/ejn.16380. Online ahead of print. Eur J Neurosci. 2024. PMID: 38752411
Resting state functional magnetic resonance imaging (R-fMRI) offers insight into how synchrony within and between brain networks is altered in disease states. Individual and disease-related variability in intrinsic connectivity networks may influence our interpretation of …
Resting state functional magnetic resonance imaging (R-fMRI) offers insight into how synchrony within and between brain networks is altered …
Is more better? A multilevel analysis of percutaneous coronary intervention hospital openings and closures on patient volumes.
Hsia RY, Redberg RF, Shen YC. Hsia RY, et al. Acad Emerg Med. 2024 May 16. doi: 10.1111/acem.14926. Online ahead of print. Acad Emerg Med. 2024. PMID: 38752293
METHODS: We conducted a retrospective cohort study of 3,966,025 Medicare Fee-For-Service patients in 37,451 zip codes and 2564 U.S. hospitals who underwent PCI from 2006 to 2017. We conducted community-, hospital-, and patient-level analyses using ordinary least squ …
METHODS: We conducted a retrospective cohort study of 3,966,025 Medicare Fee-For-Service patients in 37,451 zip codes and 2564 U.S …
Key developments and hotspots of exosomes in Alzheimer's disease: a bibliometric study spanning 2003 to 2023.
Liu S, Geng D. Liu S, et al. Front Aging Neurosci. 2024 May 1;16:1377672. doi: 10.3389/fnagi.2024.1377672. eCollection 2024. Front Aging Neurosci. 2024. PMID: 38752210 Free PMC article.
The vast majority of publications came from China and the US. The University of California System, the National Institutes of Health, and the NIH National Institute on Aging in the US were the primary research institutions. ...The Journal of Alz …
The vast majority of publications came from China and the US. The University of California System, the National Institutes of …
Friedreich Ataxia Caregiver-Reported Health Index: Development of a Novel, Disease-Specific Caregiver-Reported Outcome Measure.
Seabury J, Varma A, Weinstein J, Rosero SJ, Engebrecht C, Khosa S, Zizzi C, Wagner ES, Alexandrou D, Cohen BL, Dilek N, Heatwole JM, Lynch DR, Park CC, Wells M, Subramony SH, Heatwole CR. Seabury J, et al. Neurol Clin Pract. 2024 Jun;14(3):e200303. doi: 10.1212/CPJ.0000000000200300. Epub 2024 May 10. Neurol Clin Pract. 2024. PMID: 38751829
METHODS: In prior work, we conducted qualitative interviews and a cross-sectional study of FRDA caregivers and patients to determine the symptoms of greatest importance to individuals with FRDA. We designed the Friedreich Ataxia Caregiver-Reported Health Index (FACR-HI) to …
METHODS: In prior work, we conducted qualitative interviews and a cross-sectional study of FRDA caregivers and patients to determine the sym …
How to decrease teenage pregnancy: rural perspectives in Ecuador.
Tituaña A, Herrán K, Galárraga O, Palacios I. Tituaña A, et al. Front Public Health. 2024 May 1;12:1370507. doi: 10.3389/fpubh.2024.1370507. eCollection 2024. Front Public Health. 2024. PMID: 38751588 Free PMC article.
Additionally, 45.8% of adolescent and 80% of adult survey respondents believed that a comprehensive sexual education program would help reduce teenage pregnancy rates by imparting reliable sexual health knowledge. Adult respondents noted that the past programs were unsucce …
Additionally, 45.8% of adolescent and 80% of adult survey respondents believed that a comprehensive sexual education program would help redu …
Diabetes and gastric cancer incidence and mortality in the Asia Cohort Consortium: A pooled analysis of more than a half million participants.
De la Torre K, Song M, Abe SK, Rahman MS, Islam MR, Saito E, Min S, Huang D, Chen Y, Gupta PC, Sawada N, Tamakoshi A, Shu XO, Wen W, Sakata R, Kim J, Nagata C, Ito H, Park SK, Shin MH, Pednekar MS, Tsugane S, Kimura T, Gao YT, Cai H, Wada K, Oze I, Shin A, Ahn YO, Ahsan H, Boffetta P, Chia KS, Matsuo K, Qiao YL, Rothman N, Zheng W, Inoue M, Kang D. De la Torre K, et al. J Diabetes. 2024 Jun;16(6):e13561. doi: 10.1111/1753-0407.13561. J Diabetes. 2024. PMID: 38751364 Free PMC article.
Association of health confidence with hospital length of stay and readmission.
Brown AE, Press VG, Meltzer DO. Brown AE, et al. J Hosp Med. 2024 May 16. doi: 10.1002/jhm.13405. Online ahead of print. J Hosp Med. 2024. PMID: 38751348
OBJECTIVE: To determine if the Health Confidence Score (HCS) is associated with hospital LOS and readmission in a socioeconomically diverse population. ...MAIN OUTCOME AND MEASURES: Patient-reported responses to the HCS (scored 0 [lowest health confidence] to -12 [h …
OBJECTIVE: To determine if the Health Confidence Score (HCS) is associated with hospital LOS and readmission in a socioeconomically d …
An endogenous retrovirus regulates tumor-specific expression of the immune transcriptional regulator SP140.
Dziulko AK, Allen H, Chuong EB. Dziulko AK, et al. Hum Mol Genet. 2024 May 15:ddae084. doi: 10.1093/hmg/ddae084. Online ahead of print. Hum Mol Genet. 2024. PMID: 38751339
SP140 expression is currently thought to be restricted to immune cells. However, by analyzing human transcriptomic datasets from a wide range of normal and cancer cell types, we found recurrent cancer-specific expression of SP140, driven by an alternative intronic promoter …
SP140 expression is currently thought to be restricted to immune cells. However, by analyzing human transcriptomic datasets from a wi …
Trends in central nervous system-active polypharmacy among people with multiple sclerosis.
Naizer H, Wozny J, Krause TM, Huson E, Freeman L. Naizer H, et al. Mult Scler. 2024 May 15:13524585241251986. doi: 10.1177/13524585241251986. Online ahead of print. Mult Scler. 2024. PMID: 38751229
METHODS: This serial, cross-sectional study measured CNS-active polypharmacy in people with MS in the United States from 2008 to 2021 using insurance claims data. CNS-active polypharmacy was defined as the concurrent prescription of 3 CNS-active drugs for >30 con …
METHODS: This serial, cross-sectional study measured CNS-active polypharmacy in people with MS in the United States from 2008 …
Divergent association between pain intensity and resting-state fMRI-based brain entropy in different age groups.
Del Mauro G, Sevel LS, Boissoneault J, Wang Z. Del Mauro G, et al. J Neurosci Res. 2024 May;102(5):e25341. doi: 10.1002/jnr.25341. J Neurosci Res. 2024. PMID: 38751218
BEN was estimated from rs-fMRI data provided by two datasets with different age range: the Human Connectome Project-Young Adult (HCP-YA) and the Human Connectome project-Aging (HCP-A) datasets. ...
BEN was estimated from rs-fMRI data provided by two datasets with different age range: the Human Connectome Project-Young Adult (HCP- …
Misspellings or "miscellings"-Non-verifiable and unknown cell lines in cancer research publications.
Oste DJ, Pathmendra P, Richardson RAK, Johnson G, Ao Y, Arya MD, Enochs NR, Hussein M, Kang J, Lee A, Danon JJ, Cabanac G, Labbé C, Davis AC, Stoeger T, Byrne JA. Oste DJ, et al. Int J Cancer. 2024 May 15. doi: 10.1002/ijc.34995. Online ahead of print. Int J Cancer. 2024. PMID: 38751110
We also found 5 cell line identifiers in miR-145 papers with misidentified nucleotide sequences and cell lines, and 18 cell line identifiers published elsewhere, that did not represent indexed human cell lines. These 23 identifiers were described as non-verifiable (NV), as …
We also found 5 cell line identifiers in miR-145 papers with misidentified nucleotide sequences and cell lines, and 18 cell line identifiers …
The American College of Rheumatology White Paper: The Effects of Climate Change on Rheumatic Conditions - An Evolving Landscape and a Path Forward.
Dellaripa PF, Sung LH, Bain PA, Lanata C, Blazar A, Miller FW, Feldman CH; American College of Rheumatology Committee on Research. Dellaripa PF, et al. Arthritis Rheumatol. 2024 May 15. doi: 10.1002/art.42919. Online ahead of print. Arthritis Rheumatol. 2024. PMID: 38751102
BACKGROUND: Increases in global temperatures and extreme weather events associated with climate change have complex yet poorly understood detrimental impacts on human health. We reviewed the current published literature on climate change-related effects and rheumati …
BACKGROUND: Increases in global temperatures and extreme weather events associated with climate change have complex yet poorly understood de …
Circulating microRNA profile of long-lived Okinawans identifies novel potential targets for optimizing lifespan and health span.
Noureddine S, Schneider A, Strader S, Zhu X, Dhahbi J, Allsopp R, Willcox DC, Donlon TA, Shimabukuro M, Higa M, Suzuki M, Torigoe T, Ashiqueali S, Yadav H, Willcox BJ, Masternak MM. Noureddine S, et al. Aging Cell. 2024 May 15:e14191. doi: 10.1111/acel.14191. Online ahead of print. Aging Cell. 2024. PMID: 38751007 Free article.
Nonagenarians and centenarians serve as successful examples of aging and extended longevity, showcasing robust regulation of biological mechanisms and homeostasis. Given that human longevity is a complex field of study that navigates molecular and biological mechanisms inf …
Nonagenarians and centenarians serve as successful examples of aging and extended longevity, showcasing robust regulation of biological mech …
Ultra-processed foods, unprocessed/minimally processed foods and risk of frailty in a cohort of U.S. females.
Fung TT, Rossato SL, Chen Z, Khandpur N, Rodriguez-Artalejo F, Willett WC, Struijk EA, Lopez-Garcia E. Fung TT, et al. Am J Clin Nutr. 2024 May 13:S0002-9165(24)00468-4. doi: 10.1016/j.ajcnut.2024.05.006. Online ahead of print. Am J Clin Nutr. 2024. PMID: 38750726
METHODS: 63,743 non-frail females aged 60+ from the Nurses' Health Study (cohort study) were followed for up to 26 years. Diet was assessed every 4 years by Food Frequency Questionnaires. ...
METHODS: 63,743 non-frail females aged 60+ from the Nurses' Health Study (cohort study) were followed for up to 26 years. Diet was as …
13C-Stable isotope resolved metabolomics uncovers dynamic biochemical landscape of gut microbiome-host organ communications in mice.
Xiao X, Zhou Y, Li X, Jin J, Durham J, Ye Z, Wang Y, Hennig B, Deng P. Xiao X, et al. Microbiome. 2024 May 15;12(1):90. doi: 10.1186/s40168-024-01808-x. Microbiome. 2024. PMID: 38750595 Free PMC article.
BACKGROUND: Gut microbiome metabolites are important modulators of host health and disease. However, the overall metabolic potential of the gut microbiome and interactions with the host organs have been underexplored. ...In vitro and in silico studies revealed the de novo …
BACKGROUND: Gut microbiome metabolites are important modulators of host health and disease. However, the overall metabolic potential …
Alzheimer blood biomarkers: practical guidelines for study design, sample collection, processing, biobanking, measurement and result reporting.
Zeng X, Chen Y, Sehrawat A, Lee J, Lafferty TK, Kofler J, Berman SB, Sweet RA, Tudorascu DL, Klunk WE, Ikonomovic MD, Pfister A, Zetterberg H, Snitz BE, Cohen AD, Villemagne VL, Pascoal TA, Kamboh ML, Lopez OI, Blennow K, Karikari TK. Zeng X, et al. Mol Neurodegener. 2024 May 15;19(1):40. doi: 10.1186/s13024-024-00711-1. Mol Neurodegener. 2024. PMID: 38750570 Free PMC article. Review.
Relationship of regional ultraviolet index data with rash and systemic disease activity in youth with childhood-onset systemic lupus: results from the Childhood Arthritis and Rheumatology Research Alliance Registry.
Tanner TI, Agalliu I, Wahezi DM, Rubinstein TB. Tanner TI, et al. Pediatr Rheumatol Online J. 2024 May 15;22(1):54. doi: 10.1186/s12969-024-00973-5. Pediatr Rheumatol Online J. 2024. PMID: 38750564 Free PMC article.
METHODS: We reviewed data on rash and disease activity from Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2 K) scores from cSLE CARRA Registry participants with visits between 2010 and 2019 and obtained zipcode level UVI data from the National Oceanic an …
METHODS: We reviewed data on rash and disease activity from Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2 K) scores fro …
Optimizing deep learning-based segmentation of densely packed cells using cell surface markers.
Han S, Phasouk K, Zhu J, Fong Y. Han S, et al. BMC Med Inform Decis Mak. 2024 May 15;24(1):124. doi: 10.1186/s12911-024-02502-6. BMC Med Inform Decis Mak. 2024. PMID: 38750526 Free PMC article.
METHODS: We first assess the performance of 18 deep learning-based cell segmentation models, either pre-trained or trained by us using two public image sets, on a set of immunofluorescence images stained with immune cell surface markers in skin tissue obtained during human …
METHODS: We first assess the performance of 18 deep learning-based cell segmentation models, either pre-trained or trained by us using two p …
Overexpression of pathogenic tau in astrocytes causes a reduction in AQP4 and GLT1, an immunosuppressed phenotype and unique transcriptional responses to repetitive mild TBI without appreciable changes in tauopathy.
Ortiz C, Pearson A, McCartan R, Roche S, Carothers N, Browning M, Perez S, He B, Ginsberg SD, Mullan M, Mufson EJ, Crawford F, Ojo J. Ortiz C, et al. J Neuroinflammation. 2024 May 15;21(1):130. doi: 10.1186/s12974-024-03117-4. J Neuroinflammation. 2024. PMID: 38750510 Free PMC article.
Moreover, gene array analysis of microdissected astrocytes accrued from stage IV CTE human brains revealed an immunosuppressed astroglial phenotype similar to tau-bearing astrocytes in the GFAP(P301L) model. ...
Moreover, gene array analysis of microdissected astrocytes accrued from stage IV CTE human brains revealed an immunosuppressed astrog …
The prevalence and mortality risks of PRISm and COPD in the United States from NHANES 2007-2012.
Cadham CJ, Oh H, Han MK, Mannino D, Cook S, Meza R, Levy DT, Sánchez-Romero LM. Cadham CJ, et al. Respir Res. 2024 May 15;25(1):208. doi: 10.1186/s12931-024-02841-y. Respir Res. 2024. PMID: 38750492 Free PMC article.
METHODS: We linked three waves of pre-bronchodilator spirometry data from the US National Health and Nutritional Examination Survey (2007-2012) with the National Death Index. ...
METHODS: We linked three waves of pre-bronchodilator spirometry data from the US National Health and Nutritional Examination S …
Identification of Gα12-vs-Gα13-coupling determinants and development of a Gα12/13-coupled designer GPCR.
Tatsumi M, Cruz C, Kamakura N, Kuwabara R, Nakamura G, Ikuta T, Abrol R, Inoue A. Tatsumi M, et al. Sci Rep. 2024 May 15;14(1):11119. doi: 10.1038/s41598-024-61506-4. Sci Rep. 2024. PMID: 38750247 Free PMC article.
G-protein-coupled receptors (GPCRs) transduce diverse signals into the cell by coupling to one or several Galpha subtypes. Of the 16 Galpha subtypes in human cells, Galpha(12) and Galpha(13) belong to the G(12) subfamily and are reported to be functionally different. ...
G-protein-coupled receptors (GPCRs) transduce diverse signals into the cell by coupling to one or several Galpha subtypes. Of the 16 Galpha …
Identification of a clinically efficacious CAR T cell subset in diffuse large B cell lymphoma by dynamic multidimensional single-cell profiling.
Rezvan A, Romain G, Fathi M, Heeke D, Martinez-Paniagua M, An X, Bandey IN, Montalvo MJ, Adolacion JRT, Saeedi A, Sadeghi F, Fousek K, Puebla-Osorio N, Cooper LJN, Bernatchez C, Singh H, Ahmed N, Mattie M, Bot A, Neelapu S, Varadarajan N. Rezvan A, et al. Nat Cancer. 2024 May 15. doi: 10.1038/s43018-024-00768-3. Online ahead of print. Nat Cancer. 2024. PMID: 38750245
Sex-dependent interactions between prodromal intestinal inflammation and LRRK2 G2019S in mice promote endophenotypes of Parkinson's disease.
Fang P, Yu LW, Espey H, Agirman G, Kazmi SA, Li K, Deng Y, Lee J, Hrncir H, Romero-Lopez A, Arnold AP, Hsiao EY. Fang P, et al. Commun Biol. 2024 May 15;7(1):570. doi: 10.1038/s42003-024-06256-9. Commun Biol. 2024. PMID: 38750146 Free PMC article.
Herein, we provide evidence that prodromal intestinal inflammation expedites and exacerbates PD endophenotypes in rodent carriers of the human PD risk allele LRRK2 G2019S in a sex-dependent manner. Chronic intestinal damage in genetically predisposed male mice promotes alp …
Herein, we provide evidence that prodromal intestinal inflammation expedites and exacerbates PD endophenotypes in rodent carriers of the …
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