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Epigenetics: A new methyl mark on messengers.
Kietrys AM, Kool ET. Kietrys AM, et al. Nature. 2016 Feb 25;530(7591):423-4. doi: 10.1038/530423a. Nature. 2016. PMID: 26911777 Free PMC article.
Luminescent Carbon Dot Mimics Assembled on DNA.
Chan KM, Xu W, Kwon H, Kietrys AM, Kool ET. Chan KM, et al. Among authors: kietrys am. J Am Chem Soc. 2017 Sep 20;139(37):13147-13155. doi: 10.1021/jacs.7b07420. Epub 2017 Sep 12. J Am Chem Soc. 2017. PMID: 28841010 Free PMC article.
RNA Cloaking by Reversible Acylation.
Kadina A, Kietrys AM, Kool ET. Kadina A, et al. Among authors: kietrys am. Angew Chem Int Ed Engl. 2018 Mar 12;57(12):3059-3063. doi: 10.1002/anie.201708696. Epub 2018 Feb 22. Angew Chem Int Ed Engl. 2018. PMID: 29370460 Free PMC article.
Potent and Selective Inhibitors of 8-Oxoguanine DNA Glycosylase.
Tahara YK, Auld D, Ji D, Beharry AA, Kietrys AM, Wilson DL, Jimenez M, King D, Nguyen Z, Kool ET. Tahara YK, et al. Among authors: kietrys am. J Am Chem Soc. 2018 Feb 14;140(6):2105-2114. doi: 10.1021/jacs.7b09316. Epub 2018 Feb 5. J Am Chem Soc. 2018. PMID: 29376367 Free PMC article.
RNA Control by Photoreversible Acylation.
Velema WA, Kietrys AM, Kool ET. Velema WA, et al. Among authors: kietrys am. J Am Chem Soc. 2018 Mar 14;140(10):3491-3495. doi: 10.1021/jacs.7b12408. Epub 2018 Mar 1. J Am Chem Soc. 2018. PMID: 29474085 Free PMC article.
Dual Inhibitors of 8-Oxoguanine Surveillance by OGG1 and NUDT1.
Tahara YK, Kietrys AM, Hebenbrock M, Lee Y, Wilson DL, Kool ET. Tahara YK, et al. Among authors: kietrys am. ACS Chem Biol. 2019 Dec 20;14(12):2606-2615. doi: 10.1021/acschembio.9b00490. Epub 2019 Oct 29. ACS Chem Biol. 2019. PMID: 31622553 Free PMC article.
Reversible RNA acylation for control of CRISPR-Cas9 gene editing.
Habibian M, McKinlay C, Blake TR, Kietrys AM, Waymouth RM, Wender PA, Kool ET. Habibian M, et al. Among authors: kietrys am. Chem Sci. 2019 Dec 2;11(4):1011-1016. doi: 10.1039/c9sc03639c. Chem Sci. 2019. PMID: 34084356 Free PMC article.
Enhancing Repair of Oxidative DNA Damage with Small-Molecule Activators of MTH1.
Lee Y, Onishi Y, McPherson L, Kietrys AM, Hebenbrock M, Jun YW, Das I, Adimoolam S, Ji D, Mohsen MG, Ford JM, Kool ET. Lee Y, et al. Among authors: kietrys am. ACS Chem Biol. 2022 Aug 19;17(8):2074-2087. doi: 10.1021/acschembio.2c00038. Epub 2022 Jul 13. ACS Chem Biol. 2022. PMID: 35830623
Pervasive transcriptome interactions of protein-targeted drugs.
Fang L, Velema WA, Lee Y, Xiao L, Mohsen MG, Kietrys AM, Kool ET. Fang L, et al. Among authors: kietrys am. Nat Chem. 2023 Oct;15(10):1374-1383. doi: 10.1038/s41557-023-01309-8. Epub 2023 Aug 31. Nat Chem. 2023. PMID: 37653232