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Page 1
Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19: A Randomized Clinical Trial.
Self WH, Semler MW, Leither LM, Casey JD, Angus DC, Brower RG, Chang SY, Collins SP, Eppensteiner JC, Filbin MR, Files DC, Gibbs KW, Ginde AA, Gong MN, Harrell FE Jr, Hayden DL, Hough CL, Johnson NJ, Khan A, Lindsell CJ, Matthay MA, Moss M, Park PK, Rice TW, Robinson BRH, Schoenfeld DA, Shapiro NI, Steingrub JS, Ulysse CA, Weissman A, Yealy DM, Thompson BT, Brown SM; National Heart, Lung, and Blood Institute PETAL Clinical Trials Network; Steingrub J, Smithline H, Tiru B, Tidswell M, Kozikowski L, Thornton-Thompson S, De Souza L, Hou P, Baron R, Massaro A, Aisiku I, Fredenburgh L, Seethala R, Johnsky L, Riker R, Seder D, May T, Baumann M, Eldridge A, Lord C, Shapiro N, Talmor D, O’Mara T, Kirk C, Harrison K, Kurt L, Schermerhorn M, Banner-Goodspeed V, Boyle K, Dubosh N, Filbin M, Hibbert K, Parry B, Lavin-Parsons K, Pulido N, Lilley B, Lodenstein C, Margolin J, Brait K, Jones A, Galbraith J, Peacock R, Nandi U, Wachs T, Matthay M, Liu K, Kangelaris K, Wang R, Calfee C, Yee K, Hendey G, Chang S, Lim G, Qadir N, Tam A, Beutler R, Levitt J, Wilson J, Rogers A, Vojnik R, Roque J, Albertson T, Chenoweth J, Adams J, Pearson S, Juarez M, Almasri E, Fayed M, Hughes A, Hillar… See abstract for full author list ➔ Self WH, et al. Among authors: matthay m, matthay ma. JAMA. 2020 Dec 1;324(21):2165-2176. doi: 10.1001/jama.2020.22240. JAMA. 2020. PMID: 33165621 Free PMC article. Clinical Trial.
IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition.
Haslund-Gourley BS, Woloszczuk K, Hou J, Connors J, Cusimano G, Bell M, Taramangalam B, Fourati S, Mege N, Bernui M, Altman MC, Krammer F, van Bakel H; IMPACC Network; Maecker HT, Rouphael N, Diray-Arce J, Wigdahl B, Kutzler MA, Cairns CB, Haddad EK, Comunale MA. Haslund-Gourley BS, et al. Nat Commun. 2024 Jan 9;15(1):404. doi: 10.1038/s41467-023-44211-0. Nat Commun. 2024. PMID: 38195739 Free PMC article.
Life-saving effect of pulmonary surfactant in premature babies.
Raj JU, Bland RD, Bhattacharya J, Rabinovitch M, Matthay MA. Raj JU, et al. Among authors: matthay ma. J Clin Invest. 2024 May 1;134(9):e179948. doi: 10.1172/JCI179948. J Clin Invest. 2024. PMID: 38690742 Free PMC article. Review.
Respiratory drive heterogeneity associated with systemic inflammation and vascular permeability in acute respiratory distress syndrome.
Baedorf-Kassis E, Murn M, Dzierba AL, Serra AL, Garcia I, Minus E, Padilla C, Sarge T, Goodspeed VM, Matthay MA, Gong MN, Cook D, Loring SH, Talmor D, Beitler JR; EPVent-2 Study Group. Baedorf-Kassis E, et al. Among authors: matthay ma. Crit Care. 2024 Apr 23;28(1):136. doi: 10.1186/s13054-024-04920-4. Crit Care. 2024. PMID: 38654391 Free PMC article.
Rapidly improving ARDS differs clinically and biologically from persistent ARDS.
Valda Toro PL, Willmore A, Wu NE, Delucchi KL, Jauregui A, Sinha P, Liu KD, Hendrickson CM, Sarma A, Neyton LPA, Leligdowicz A, Langelier CR, Zhuo H, Jones C, Kangelaris KN, Gomez AD, Matthay MA, Calfee CS. Valda Toro PL, et al. Among authors: matthay ma. Crit Care. 2024 Apr 22;28(1):132. doi: 10.1186/s13054-024-04883-6. Crit Care. 2024. PMID: 38649920 Free PMC article.
Timing of antibiotic treatment identifies distinct clinical presentations among patients presenting with suspected septic shock.
Prasad PA, Esmaili AM, Oreper S, Beagle AJ, Hubbard C, Raffel KE, Abe-Jones Y, Fang MC, Liu KD, Matthay MA, Kangelaris KN. Prasad PA, et al. Among authors: matthay ma. J Am Coll Emerg Physicians Open. 2024 Apr 9;5(2):e13149. doi: 10.1002/emp2.13149. eCollection 2024 Apr. J Am Coll Emerg Physicians Open. 2024. PMID: 38596320 Free PMC article.
Reply to Du, et al. and Palanidurai, et al.
Matthay MA, Ware LB, Riviello ED, Wick KD, Thompson T, Martin TR. Matthay MA, et al. Am J Respir Crit Care Med. 2024 Mar 20. doi: 10.1164/rccm.202402-0284LE. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 38507735 No abstract available.
Biological Effects of Corticosteroids on Pneumococcal Pneumonia in Mice and Humans.
Taenaka H, Wick KD, Sarma A, Matsumoto S, Ghale R, Fang X, Maishan M, Gotts JE, Langelier CR, Calfee CS, Matthay MA. Taenaka H, et al. Among authors: matthay ma. Res Sq [Preprint]. 2024 Feb 21:rs.3.rs-3962861. doi: 10.21203/rs.3.rs-3962861/v1. Res Sq. 2024. PMID: 38464245 Free PMC article. Preprint.
Novel subtypes of severe COVID-19 respiratory failure based on biological heterogeneity: a secondary analysis of a randomized controlled trial.
Alipanah-Lechner N, Hurst-Hopf J, Delucchi K, Swigart L, Willmore A, LaCombe B, Dewar R, Lane HC, Lallemand P, Liu KD, Esserman L, Matthay MA, Calfee CS; I-SPY COVID Consortium. Alipanah-Lechner N, et al. Among authors: matthay ma. Crit Care. 2024 Feb 21;28(1):56. doi: 10.1186/s13054-024-04819-0. Crit Care. 2024. PMID: 38383504 Free PMC article. Clinical Trial.
Molecular Phenotypes of Acute Respiratory Distress Syndrome in the ROSE Trial Have Differential Outcomes and Gene Expression Patterns That Differ at Baseline and Longitudinally over Time.
Sinha P, Neyton L, Sarma A, Wu N, Jones C, Zhuo H, Liu KD, Sanchez Guerrero E, Ghale R, Love C, Mick E, Delucchi KL, Langelier CR, Thompson BT, Matthay MA, Calfee CS. Sinha P, et al. Among authors: matthay ma. Am J Respir Crit Care Med. 2024 Apr 1;209(7):816-828. doi: 10.1164/rccm.202308-1490OC. Am J Respir Crit Care Med. 2024. PMID: 38345571
The Plasma Lipidomic Landscape in Patients with Sepsis due to Community-acquired Pneumonia.
Chouchane O, Schuurman AR, Reijnders TDY, Peters-Sengers H, Butler JM, Uhel F, Schultz MJ, Bonten MJ, Cremer OL, Calfee CS, Matthay MA, Langley RJ, Alipanah-Lechner N, Kingsmore SF, Rogers A, van Weeghel M, Vaz FM, van der Poll T. Chouchane O, et al. Among authors: matthay ma. Am J Respir Crit Care Med. 2024 Apr 15;209(8):973-986. doi: 10.1164/rccm.202308-1321OC. Am J Respir Crit Care Med. 2024. PMID: 38240721
Host and Microbe Blood Metagenomics Reveals Key Pathways Characterizing Critical Illness Phenotypes.
Neyton LPA, Sinha P, Sarma A, Mick E, Kalantar K, Chen S, Wu N, Delucchi K, Zhuo H, Bos LDJ, Jauregui A, Gomez A, Hendrickson CM, Kangelaris KN, Leligdowicz A, Liu KD, Matthay MA, Langelier CR, Calfee CS. Neyton LPA, et al. Among authors: matthay ma. Am J Respir Crit Care Med. 2024 Apr 1;209(7):805-815. doi: 10.1164/rccm.202308-1328OC. Am J Respir Crit Care Med. 2024. PMID: 38190719
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study.
Ozonoff A, Jayavelu ND, Liu S, Melamed E, Milliren CE, Qi J, Geng LN, McComsey GA, Cairns CB, Baden LR, Schaenman J, Shaw AC, Samaha H, Seyfert-Margolis V, Krammer F, Rosen LB, Steen H, Syphurs C, Dandekar R, Shannon CP, Sekaly RP, Ehrlich LIR, Corry DB, Kheradmand F, Atkinson MA, Brakenridge SC, Higuita NIA, Metcalf JP, Hough CL, Messer WB, Pulendran B, Nadeau KC, Davis MM, Sesma AF, Simon V, van Bakel H, Kim-Schulze S, Hafler DA, Levy O, Kraft M, Bime C, Haddad EK, Calfee CS, Erle DJ, Langelier CR, Eckalbar W, Bosinger SE; IMPACC Network; Peters B, Kleinstein SH, Reed EF, Augustine AD, Diray-Arce J, Maecker HT, Altman MC, Montgomery RR, Becker PM, Rouphael N. Ozonoff A, et al. Nat Commun. 2024 Jan 3;15(1):216. doi: 10.1038/s41467-023-44090-5. Nat Commun. 2024. PMID: 38172101 Free PMC article.
Elevated ferritin, mediated by IL-18 is associated with systemic inflammation and mortality in acute respiratory distress syndrome (ARDS).
Mehta P, Samanta RJ, Wick K, Coll RC, Mawhinney T, McAleavey PG, Boyle AJ, Conlon J, Shankar-Hari M, Rogers A, Calfee CS, Matthay MA, Summers C, Chambers RC, McAuley DF, O'Kane CM. Mehta P, et al. Among authors: matthay ma. Thorax. 2024 Feb 15;79(3):227-235. doi: 10.1136/thorax-2023-220292. Thorax. 2024. PMID: 38148147
The Translational Value of Rodent Models of Sepsis.
Matthay MA, Schmidt EP, Bastarache JA, Calfee CS, Frevert CW, Martin TR. Matthay MA, et al. Am J Respir Crit Care Med. 2024 Mar 1;209(5):488-490. doi: 10.1164/rccm.202308-1489VP. Am J Respir Crit Care Med. 2024. PMID: 38091521 Free PMC article. No abstract available.
Unraveling the enigma of genetics and phenotypes in ARDS.
Artigas A, Barbas CSV, Matthay MA. Artigas A, et al. Among authors: matthay ma. Intensive Care Med. 2024 Jan;50(1):125-127. doi: 10.1007/s00134-023-07277-4. Epub 2023 Dec 12. Intensive Care Med. 2024. PMID: 38085336 No abstract available.
In vivo protein turnover rates in varying oxygen tensions nominate MYBBP1A as a mediator of the hyperoxia response.
Chen X, Haribowo AG, Baik AH, Fossati A, Stevenson E, Chen YR, Reyes NS, Peng T, Matthay MA, Traglia M, Pico AR, Jarosz DF, Buchwalter A, Ghaemmaghami S, Swaney DL, Jain IH. Chen X, et al. Among authors: matthay ma. Sci Adv. 2023 Dec 8;9(49):eadj4884. doi: 10.1126/sciadv.adj4884. Epub 2023 Dec 8. Sci Adv. 2023. PMID: 38064566 Free PMC article.
Effect of Neutralizing Monoclonal Antibody Treatment on Early Trajectories of Virologic and Immunologic Biomarkers in Patients Hospitalized With COVID-19.
Jensen TO, Grandits GA, Jain MK, Murray TA, Grund B, Shaw-Saliba K, Matthay MA, Abassi M, Ardelt M, Baker JV, Chen P, Dewar RL, Goodman AL, Hatlen TJ, Highbarger HC, Holodniy M, Lallemand P, Laverdure S, Leshnower BG, Looney D, Moschopoulos CD, Mugerwa H, Murray DD, Mylonakis E, Nagy-Agren S, Rehman MT, Rupert A, Stevens RA, Turville S, Weintrob A, Wick K, Lundgren J, Ko ER; ACTIV-3/TICO Study Group. Jensen TO, et al. Among authors: matthay ma. J Infect Dis. 2024 Mar 14;229(3):671-679. doi: 10.1093/infdis/jiad446. J Infect Dis. 2024. PMID: 37948759 Free PMC article. Clinical Trial.
The antibiotic resistance reservoir of the lung microbiome expands with age.
Chu VT, Tsitsiklis A, Mick E, Ambroggio L, Kalantar KL, Glascock A, Osborne CM, Wagner BD, Matthay MA, DeRisi JL, Calfee CS, Mourani PM, Langelier CR. Chu VT, et al. Among authors: matthay ma. Res Sq [Preprint]. 2023 Sep 18:rs.3.rs-3283415. doi: 10.21203/rs.3.rs-3283415/v1. Res Sq. 2023. PMID: 37790384 Free PMC article. Updated. Preprint.
MicroRNA-1 protects the endothelium in acute lung injury.
Korde A, Haslip M, Pednekar P, Khan A, Chioccioli M, Mehta S, Lopez-Giraldez F, Bermejo S, Rojas M, Dela Cruz C, Matthay MA, Pober JS, Pierce RW, Takyar SS. Korde A, et al. Among authors: matthay ma. JCI Insight. 2023 Sep 22;8(18):e164816. doi: 10.1172/jci.insight.164816. JCI Insight. 2023. PMID: 37737266 Free PMC article.
Elevated Plasma Interleukin-18 Identifies High-Risk Acute Respiratory Distress Syndrome Patients not Distinguished by Prior Latent Class Analyses Using Traditional Inflammatory Cytokines: A Retrospective Analysis of Two Randomized Clinical Trials.
Moore AR, Pienkos SM, Sinha P, Guan J, O'Kane CM, Levitt JE, Wilson JG, Shankar-Hari M, Matthay MA, Calfee CS, Baron RM, McAuley DF, Rogers AJ. Moore AR, et al. Among authors: matthay ma. Crit Care Med. 2023 Dec 1;51(12):e269-e274. doi: 10.1097/CCM.0000000000006028. Epub 2023 Sep 11. Crit Care Med. 2023. PMID: 37695136
Identifying molecular phenotypes in sepsis: an analysis of two prospective observational cohorts and secondary analysis of two randomised controlled trials.
Sinha P, Kerchberger VE, Willmore A, Chambers J, Zhuo H, Abbott J, Jones C, Wickersham N, Wu N, Neyton L, Langelier CR, Mick E, He J, Jauregui A, Churpek MM, Gomez AD, Hendrickson CM, Kangelaris KN, Sarma A, Leligdowicz A, Delucchi KL, Liu KD, Russell JA, Matthay MA, Walley KR, Ware LB, Calfee CS. Sinha P, et al. Among authors: matthay ma. Lancet Respir Med. 2023 Nov;11(11):965-974. doi: 10.1016/S2213-2600(23)00237-0. Epub 2023 Aug 23. Lancet Respir Med. 2023. PMID: 37633303
A New Global Definition of Acute Respiratory Distress Syndrome.
Matthay MA, Arabi Y, Arroliga AC, Bernard G, Bersten AD, Brochard LJ, Calfee CS, Combes A, Daniel BM, Ferguson ND, Gong MN, Gotts JE, Herridge MS, Laffey JG, Liu KD, Machado FR, Martin TR, McAuley DF, Mercat A, Moss M, Mularski RA, Pesenti A, Qiu H, Ramakrishnan N, Ranieri VM, Riviello ED, Rubin E, Slutsky AS, Thompson BT, Twagirumugabe T, Ware LB, Wick KD. Matthay MA, et al. Am J Respir Crit Care Med. 2024 Jan 1;209(1):37-47. doi: 10.1164/rccm.202303-0558WS. Am J Respir Crit Care Med. 2024. PMID: 37487152 Free PMC article.
Clinical and biological heterogeneity of multisystem inflammatory syndrome in adults following SARS-CoV-2 infection: a case series.
Barth KE, Spottiswoode N, Hurabielle C, Subbaraj L; COMET Consortium; Calfee CS, Matthay MA, French S, Connolly A, Hewitt SM, Vannella KM, Barnett C, Langelier CR, Patterson S. Barth KE, et al. Among authors: matthay ma. Front Med (Lausanne). 2023 Jul 6;10:1187420. doi: 10.3389/fmed.2023.1187420. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37484839 Free PMC article.
Exposure to ambient air pollutants and acute respiratory distress syndrome risk in sepsis.
Reilly JP, Zhao Z, Shashaty MGS, Koyama T, Jones TK, Anderson BJ, Ittner CA, Dunn T, Miano TA, Oniyide O, Balmes JR, Matthay MA, Calfee CS, Christie JD, Meyer NJ, Ware LB. Reilly JP, et al. Among authors: matthay ma. Intensive Care Med. 2023 Aug;49(8):957-965. doi: 10.1007/s00134-023-07148-y. Epub 2023 Jul 20. Intensive Care Med. 2023. PMID: 37470831
Intravenous aviptadil and remdesivir for treatment of COVID-19-associated hypoxaemic respiratory failure in the USA (TESICO): a randomised, placebo-controlled trial.
Brown SM, Barkauskas CE, Grund B, Sharma S, Phillips AN, Leither L, Peltan ID, Lanspa M, Gilstrap DL, Mourad A, Lane K, Beitler JR, Serra AL, Garcia I, Almasri E, Fayed M, Hubel K, Harris ES, Middleton EA, Barrios MAG, Mathews KS, Goel NN, Acquah S, Mosier J, Hypes C, Salvagio Campbell E, Khan A, Hough CL, Wilson JG, Levitt JE, Duggal A, Dugar S, Goodwin AJ, Terry C, Chen P, Torbati S, Iyer N, Sandkovsky US, Johnson NJ, Robinson BRH, Matthay MA, Aggarwal NR, Douglas IS, Casey JD, Hache-Marliere M, Georges Youssef J, Nkemdirim W, Leshnower B, Awan O, Pannu S, O'Mahony DS, Manian P, Awori Hayanga JW, Wortmann GW, Tomazini BM, Miller RF, Jensen JU, Murray DD, Bickell NA, Zatakia J, Burris S, Higgs ES, Natarajan V, Dewar RL, Schechner A, Kang N, Arenas-Pinto A, Hudson F, Ginde AA, Self WH, Rogers AJ, Oldmixon CF, Morin H, Sanchez A, Weintrob AC, Cavalcanti AB, Davis-Karim A, Engen N, Denning E, Taylor Thompson B, Gelijns AC, Kan V, Davey VJ, Lundgren JD, Babiker AG, Neaton JD, Lane HC; ACTIV-3b/Therapeutics for Severely Ill Inpatients with COVID-19 (TESICO) Study Group. Brown SM, et al. Among authors: matthay ma. Lancet Respir Med. 2023 Sep;11(9):791-803. doi: 10.1016/S2213-2600(23)00147-9. Epub 2023 Jun 19. Lancet Respir Med. 2023. PMID: 37348524 Clinical Trial.
ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies.
Grasselli G, Calfee CS, Camporota L, Poole D, Amato MBP, Antonelli M, Arabi YM, Baroncelli F, Beitler JR, Bellani G, Bellingan G, Blackwood B, Bos LDJ, Brochard L, Brodie D, Burns KEA, Combes A, D'Arrigo S, De Backer D, Demoule A, Einav S, Fan E, Ferguson ND, Frat JP, Gattinoni L, Guérin C, Herridge MS, Hodgson C, Hough CL, Jaber S, Juffermans NP, Karagiannidis C, Kesecioglu J, Kwizera A, Laffey JG, Mancebo J, Matthay MA, McAuley DF, Mercat A, Meyer NJ, Moss M, Munshi L, Myatra SN, Ng Gong M, Papazian L, Patel BK, Pellegrini M, Perner A, Pesenti A, Piquilloud L, Qiu H, Ranieri MV, Riviello E, Slutsky AS, Stapleton RD, Summers C, Thompson TB, Valente Barbas CS, Villar J, Ware LB, Weiss B, Zampieri FG, Azoulay E, Cecconi M; European Society of Intensive Care Medicine Taskforce on ARDS. Grasselli G, et al. Among authors: matthay ma. Intensive Care Med. 2023 Jul;49(7):727-759. doi: 10.1007/s00134-023-07050-7. Epub 2023 Jun 16. Intensive Care Med. 2023. PMID: 37326646 Free PMC article.
Early plasma angiopoietin-2 is prognostic for ARDS and mortality among critically ill patients with sepsis.
Rosenberger CM, Wick KD, Zhuo H, Wu N, Chen Y, Kapadia SB, Guimaraes A, Chang D, Choy DF, Chen H, Peck M, Sullivan KM, Ke S, Jauregui A, Leligdowicz A, Sinha P, Gomez AD, Kangelaris KN, Delucchi K, Liu KD, Calfee CS, Matthay MA, Hendrickson CM. Rosenberger CM, et al. Among authors: matthay ma. Crit Care. 2023 Jun 13;27(1):234. doi: 10.1186/s13054-023-04525-3. Crit Care. 2023. PMID: 37312169 Free PMC article.
Impaired alveolar macrophage 11β-hydroxysteroid dehydrogenase type 1 reductase activity contributes to increased pulmonary inflammation and mortality in sepsis-related ARDS.
Mahida RY, Lax S, Bassford CR, Scott A, Parekh D, Hardy RS, Naidu B, Matthay MA, Stewart PM, Cooper MC, Perkins GD, Thickett DR. Mahida RY, et al. Among authors: matthay ma. Front Immunol. 2023 Apr 27;14:1159831. doi: 10.3389/fimmu.2023.1159831. eCollection 2023. Front Immunol. 2023. PMID: 37180160 Free PMC article.
Association of SARS-CoV-2 nucleocapsid viral antigen and the receptor for advanced glycation end products with development of severe disease in patients presenting to the emergency department with COVID-19.
Matthay ZA, Fields AT, Wick KD, Jones C, Lane HC, Herrera K, Nuñez-Garcia B, Gennatas E, Hendrickson CM, Kornblith AE, Matthay MA, Kornblith LZ; COVID-19 Associated Coagulopathy Inflammation Thrombosis (Co-ACIT) Study Group. Matthay ZA, et al. Among authors: matthay ma. Front Immunol. 2023 Mar 21;14:1130821. doi: 10.3389/fimmu.2023.1130821. eCollection 2023. Front Immunol. 2023. PMID: 37026003 Free PMC article.
Effects of the circulating environment of COVID-19 on platelet and neutrophil behavior.
Fields AT, Andraska EA, Kaltenmeier C, Matthay ZA, Herrera K, Nuñez-Garcia B, Jones CM, Wick KD, Liu S, Luo JH, Yu YP, Matthay MA, Hendrickson CM, Bainton RJ, Barrett TJ, Berger JS, Neal MD, Kornblith LZ. Fields AT, et al. Among authors: matthay ma, matthay za. Front Immunol. 2023 Mar 14;14:1130288. doi: 10.3389/fimmu.2023.1130288. eCollection 2023. Front Immunol. 2023. PMID: 36999030 Free PMC article.
Aerosolized nicotine from e-cigarettes alters gene expression, increases lung protein permeability, and impairs viral clearance in murine influenza infection.
Maishan M, Sarma A, Chun LF, Caldera S, Fang X, Abbott J, Christenson SA, Langelier CR, Calfee CS, Gotts JE, Matthay MA. Maishan M, et al. Among authors: matthay ma. Front Immunol. 2023 Mar 14;14:1076772. doi: 10.3389/fimmu.2023.1076772. eCollection 2023. Front Immunol. 2023. PMID: 36999019 Free PMC article.
Heterogeneous Treatment Effects of Therapeutic-Dose Heparin in Patients Hospitalized for COVID-19.
Goligher EC, Lawler PR, Jensen TP, Talisa V, Berry LR, Lorenzi E, McVerry BJ, Chang CH, Leifer E, Bradbury C, Berger J, Hunt BJ, Castellucci LA, Kornblith LZ, Gordon AC, McArthur C, Webb S, Hochman J, Neal MD, Zarychanski R, Berry S, Angus DC; REMAP-CAP, ATTACC, and ACTIV-4a Investigators. Goligher EC, et al. JAMA. 2023 Apr 4;329(13):1066-1077. doi: 10.1001/jama.2023.3651. JAMA. 2023. PMID: 36942550 Free PMC article.
Assessment of Symptom, Disability, and Financial Trajectories in Patients Hospitalized for COVID-19 at 6 Months.
Admon AJ, Iwashyna TJ, Kamphuis LA, Gundel SJ, Sahetya SK, Peltan ID, Chang SY, Han JH, Vranas KC, Mayer KP, Hope AA, Jolley SE, Caldwell E, Monahan ML, Hauschildt K, Brown SM, Aggarwal NR, Thompson BT, Hough CL; National Heart, Lung, and Blood Institute PETAL Network. Admon AJ, et al. JAMA Netw Open. 2023 Feb 1;6(2):e2255795. doi: 10.1001/jamanetworkopen.2022.55795. JAMA Netw Open. 2023. PMID: 36787143 Free PMC article.
Are circulating endothelial cells the next target for transcriptome-level pathway analysis in ARDS?
Costa Monteiro AC, Matthay MA. Costa Monteiro AC, et al. Among authors: matthay ma. Am J Physiol Lung Cell Mol Physiol. 2023 Apr 1;324(4):L393-L399. doi: 10.1152/ajplung.00353.2022. Epub 2023 Feb 7. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 36749906 Free PMC article. Review.
Acute respiratory distress syndrome (ARDS) has had no mortality-improving pharmacological intervention despite 50 years of high-caliber research due to its heterogeneity (Huppert LA, Matthay MA, Ware LB. Semin Respir Crit Care Med 40: 31-39, 2019). ...Am J Respir Cr …
Acute respiratory distress syndrome (ARDS) has had no mortality-improving pharmacological intervention despite 50 years of high-caliber rese …
Mechanisms of impaired alveolar fluid clearance.
Taenaka H, Matthay MA. Taenaka H, et al. Among authors: matthay ma. Anat Rec (Hoboken). 2023 Jan 23:10.1002/ar.25166. doi: 10.1002/ar.25166. Online ahead of print. Anat Rec (Hoboken). 2023. PMID: 36688689 Free article.
Tight Glycemic Control, Inflammation, and the ICU: Evidence for Heterogeneous Treatment Effects in Two Randomized Controlled Trials.
Zinter MS, Markovic D, Asaro LA, Nadkarni VM, McQuillen PS, Sinha P, Matthay MA, Jeschke MG, Agus MSD, Sapru A; CAF-PINT Investigators of the PALISI Network. Zinter MS, et al. Among authors: matthay ma. Am J Respir Crit Care Med. 2023 Apr 1;207(7):945-949. doi: 10.1164/rccm.202210-1988LE. Am J Respir Crit Care Med. 2023. PMID: 36656551 Free PMC article. No abstract available.
Plasma metabolic profiling implicates dysregulated lipid metabolism and glycolytic shift in hyperinflammatory ARDS.
Alipanah-Lechner N, Neyton L, Mick E, Willmore A, Leligdowicz A, Contrepois K, Jauregui A, Zhuo H, Hendrickson C, Gomez A, Sinha P, Kangelaris KN, Liu KD, Matthay MA, Rogers AJ, Calfee CS. Alipanah-Lechner N, et al. Among authors: matthay ma. Am J Physiol Lung Cell Mol Physiol. 2023 Mar 1;324(3):L297-L306. doi: 10.1152/ajplung.00278.2022. Epub 2023 Jan 17. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 36648136 Free PMC article.
Association Between Shared Decision-Making During Family Meetings and Surrogates' Trust in Their ICU Physician.
Lincoln TE, Buddadhumaruk P, Arnold RM, Scheunemann LP, Ernecoff NC, Chang CH, Carson SS, Hough CL, Curtis JR, Anderson W, Steingrub J, Peterson MW, Lo B, Matthay MA, White DB. Lincoln TE, et al. Among authors: matthay ma. Chest. 2023 May;163(5):1214-1224. doi: 10.1016/j.chest.2022.10.028. Epub 2022 Nov 3. Chest. 2023. PMID: 36336000 Free PMC article.
Integrated host-microbe plasma metagenomics for sepsis diagnosis in a prospective cohort of critically ill adults.
Kalantar KL, Neyton L, Abdelghany M, Mick E, Jauregui A, Caldera S, Serpa PH, Ghale R, Albright J, Sarma A, Tsitsiklis A, Leligdowicz A, Christenson SA, Liu K, Kangelaris KN, Hendrickson C, Sinha P, Gomez A, Neff N, Pisco A, Doernberg SB, Derisi JL, Matthay MA, Calfee CS, Langelier CR. Kalantar KL, et al. Among authors: matthay ma. Nat Microbiol. 2022 Nov;7(11):1805-1816. doi: 10.1038/s41564-022-01237-2. Epub 2022 Oct 20. Nat Microbiol. 2022. PMID: 36266337 Free PMC article. Clinical Trial.
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