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Cellular and molecular mechanisms of immune dysregulation and autoimmunity.
Azizi G, Pouyani MR, Abolhassani H, Sharifi L, Dizaji MZ, Mohammadi J, Mirshafiey A, Aghamohammadi A. Azizi G, et al. Among authors: mirshafiey a. Cell Immunol. 2016 Dec;310:14-26. doi: 10.1016/j.cellimm.2016.08.012. Epub 2016 Aug 27. Cell Immunol. 2016. PMID: 27614846 Review.
Modification of Sexual Hormones in Rheumatoid Arthritis Patients by M2000 (β-D-mannuronic Acid) as a Novel NSAID with Immunosuppressive Property.
Jahanbakhshi M, Babaloo Z, Mortazavi-Jahromi SS, Shokri MM, Ahmadi H, Mirshafiey A. Jahanbakhshi M, et al. Among authors: mirshafiey a. Endocr Metab Immune Disord Drug Targets. 2018;18(5):530-536. doi: 10.2174/1871530318666180418111354. Endocr Metab Immune Disord Drug Targets. 2018. PMID: 29667557 Clinical Trial.
A phase I/II randomized, controlled, clinical trial for assessment of the efficacy and safety of β-D-mannuronic acid in rheumatoid arthritis patients.
Ahmadi H, Jamshidi AR, Gharibdoost F, Mahmoudi M, Rastkari N, Mostafaei S, Fattahi MJ, Vojdanian M, Cuzzocrea S, Rehm BHA, Matsuo H, Hosseini M, Aghazadeh Z, Mortazavi-Jahromi SS, Mirshafiey A. Ahmadi H, et al. Among authors: mirshafiey a. Inflammopharmacology. 2018 Jun;26(3):737-745. doi: 10.1007/s10787-018-0475-z. Epub 2018 Apr 25. Inflammopharmacology. 2018. PMID: 29696564 Clinical Trial.
Effect of β-D-Mannuronic Acid (M2000) on Oxidative Stress Enzymes' Gene Using Healthy Donor Peripheral Blood Mononuclear Cells for Evaluating the Anti-Aging Property.
Taeb M, Jafarzadeh A, Mortazavi-Jahromi SS, Zainodini N, Mirzaei MR, Jafarnezhad-Ansariha F, Aghazadeh Z, Mirshafiey A. Taeb M, et al. Among authors: mirshafiey a. Curr Drug Discov Technol. 2019;16(3):265-271. doi: 10.2174/1570163815666180515122834. Curr Drug Discov Technol. 2019. PMID: 29766814
Anti-diabetic effect of β-D-mannuronic acid (M2000) as a novel NSAID with immunosuppressive property on insulin production, blood glucose, and inflammatory markers in the experimental diabetes model.
Mortazavi-Jahromi SS, Alizadeh S, Javanbakht MH, Mirshafiey A. Mortazavi-Jahromi SS, et al. Among authors: mirshafiey a. Arch Physiol Biochem. 2019 Dec;125(5):435-440. doi: 10.1080/13813455.2018.1481094. Epub 2018 Jun 8. Arch Physiol Biochem. 2019. PMID: 29882437
International multicenter randomized, placebo-controlled phase III clinical trial of β-D-mannuronic acid in rheumatoid arthritis patients.
Rezaieyazdi Z, Farooqi A, Soleymani-Salehabadi H, Ahmadzadeh A, Aslani M, Omidian S, Sadoughi A, Vahidi Z, Khodashahi M, Zamurrad S, Mortazavi-Jahromi SS, Fallahzadeh H, Hosseini M, Aghazadeh Z, Ekhtiari P, Matsuo H, Rehm BHA, Cuzzocrea S, D'Aniello A, Mirshafiey A. Rezaieyazdi Z, et al. Among authors: mirshafiey a. Inflammopharmacology. 2019 Oct;27(5):911-921. doi: 10.1007/s10787-018-00557-2. Epub 2019 Jan 2. Inflammopharmacology. 2019. PMID: 30604197 Clinical Trial.
Immunopharmacological effect of β-d-mannuronic acid (M2000), as a new immunosuppressive drug, on gene expression of miR-155 and its target molecules (SOCS1, SHIP1) in a clinical trial on rheumatoid arthritis patients.
Mortazavi-Jahromi SS, Aslani M, Omidian S, Ahmadzadeh A, Rezaieyazdi Z, Mirshafiey A. Mortazavi-Jahromi SS, et al. Among authors: mirshafiey a. Drug Dev Res. 2020 May;81(3):295-304. doi: 10.1002/ddr.21619. Epub 2019 Nov 1. Drug Dev Res. 2020. PMID: 31675124 Clinical Trial.
The Situation of Chemokine Ligands and Receptors Gene Expression, Following the Oral Administration of Drug Mannuronic Acid in Rheumatoid Arthritis Patients.
Aslani M, Ahmadzadeh A, Rezaieyazdi Z, Mortazavi-Jahromi SS, Barati A, Hosseini M, Mirshafiey A. Aslani M, et al. Among authors: mirshafiey a. Recent Pat Inflamm Allergy Drug Discov. 2020;14(1):69-77. doi: 10.2174/1872213X13666191114111822. Recent Pat Inflamm Allergy Drug Discov. 2020. PMID: 31729947 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 31994101
Mannuronic Acid in Low-Risk and Intermediate-1-Risk Myelodysplastic Syndromes.
Ghaderi A, Nodehi SRS, Bakhtiari T, Aslani M, Aghazadeh Z, Matsuo H, Rehm BHA, Cuzzocrea S, Mirshafiey A. Ghaderi A, et al. Among authors: mirshafiey a. J Clin Pharmacol. 2020 Jul;60(7):879-888. doi: 10.1002/jcph.1587. Epub 2020 Feb 16. J Clin Pharmacol. 2020. PMID: 32064621 Clinical Trial.
The role of β-d-mannuronic acid, as a new non-steroidal anti-inflammatory drug on expression of miR-146a, IRAK1, TRAF6, NF-κB and pro-inflammatory cytokines following a clinical trial in rheumatoid arthritis patients.
Mortazavi-Jahromi SS, Ahmadzadeh A, Rezaieyazdi Z, Aslani M, Omidian S, Mirshafiey A. Mortazavi-Jahromi SS, et al. Among authors: mirshafiey a. Immunopharmacol Immunotoxicol. 2020 Jun;42(3):228-236. doi: 10.1080/08923973.2020.1742734. Epub 2020 Mar 29. Immunopharmacol Immunotoxicol. 2020. PMID: 32223462 Clinical Trial.
Antioxidant therapy in multiple sclerosis.
Mirshafiey A, Mohsenzadegan M. Mirshafiey A, et al. Immunopharmacol Immunotoxicol. 2009;31(1):13-29. doi: 10.1080/08923970802331943. Immunopharmacol Immunotoxicol. 2009. PMID: 18763202 Review.
Autoantigens and autoantibodies in multiple sclerosis.
Mirshafiey A, Kianiaslani M. Mirshafiey A, et al. Iran J Allergy Asthma Immunol. 2013 Aug 28;12(4):292-303. Iran J Allergy Asthma Immunol. 2013. PMID: 23996705 Free article. Review.
EBV and vitamin D status in relapsing-remitting multiple sclerosis patients with a unique cytokine signature.
Nejati A, Shoja Z, Shahmahmoodi S, Tafakhori A, Mollaei-Kandelous Y, Rezaei F, Hamid KM, Mirshafiey A, Doosti R, Sahraian MA, Mahmoudi M, Shokri F, Emery V, Marashi SM. Nejati A, et al. Among authors: mirshafiey a. Med Microbiol Immunol. 2016 Apr;205(2):143-54. doi: 10.1007/s00430-015-0437-7. Epub 2015 Sep 13. Med Microbiol Immunol. 2016. PMID: 26365612
Autoimmunity in primary T-cell immunodeficiencies.
Azizi G, Ghanavatinejad A, Abolhassani H, Yazdani R, Rezaei N, Mirshafiey A, Aghamohammadi A. Azizi G, et al. Among authors: mirshafiey a. Expert Rev Clin Immunol. 2016 Sep;12(9):989-1006. doi: 10.1080/1744666X.2016.1177458. Epub 2016 Apr 28. Expert Rev Clin Immunol. 2016. PMID: 27063703 Review.
Autoimmunity in Primary Antibody Deficiencies.
Azizi G, Ahmadi M, Abolhassani H, Yazdani R, Mohammadi H, Mirshafiey A, Rezaei N, Aghamohammadi A. Azizi G, et al. Among authors: mirshafiey a. Int Arch Allergy Immunol. 2016;171(3-4):180-193. doi: 10.1159/000453263. Epub 2016 Dec 24. Int Arch Allergy Immunol. 2016. PMID: 28013299 Free article. Review.
Monogenic Auto-inflammatory Syndromes: A Review of the Literature.
Azizi G, Khadem Azarian S, Nazeri S, Mosayebian A, Ghiasy S, Sadri G, Mohebi A, Khan Nazer NH, Afraei S, Mirshafiey A. Azizi G, et al. Among authors: mirshafiey a. Iran J Allergy Asthma Immunol. 2016 Dec;15(6):430-444. Iran J Allergy Asthma Immunol. 2016. PMID: 28129677 Free article. Review.
Abnormality of regulatory T cells in common variable immunodeficiency.
Azizi G, Hafezi N, Mohammadi H, Yazdani R, Alinia T, Tavakol M, Aghamohammadi A, Mirshafiey A. Azizi G, et al. Among authors: mirshafiey a. Cell Immunol. 2017 May;315:11-17. doi: 10.1016/j.cellimm.2016.12.007. Epub 2016 Dec 29. Cell Immunol. 2017. PMID: 28284485 Review.
The potent suppressive effect of β-d-mannuronic acid (M2000) on molecular expression of the TLR/NF-kB Signaling Pathway in ankylosing spondylitis patients.
Roozbehkia M, Mahmoudi M, Aletaha S, Rezaei N, Fattahi MJ, Jafarnezhad-Ansariha F, Barati A, Mirshafiey A. Roozbehkia M, et al. Among authors: mirshafiey a. Int Immunopharmacol. 2017 Nov;52:191-196. doi: 10.1016/j.intimp.2017.08.018. Epub 2017 Sep 20. Int Immunopharmacol. 2017. PMID: 28938189 Clinical Trial.
Immunotherapeutic Effects of β-D Mannuronic Acid on IL-4, GATA3, IL-17 and RORC Gene Expression in the PBMC of Patients with Inflammatory Bowel Diseases.
Alhassan Mohammed H, Saboor-Yaraghi AA, Vahedi H, Panahi G, Hemmasi G, Yekaninejad MS, Mirshafiey A. Alhassan Mohammed H, et al. Among authors: mirshafiey a. Iran J Allergy Asthma Immunol. 2018 Aug 12;17(4):308-317. doi: 10.18502/ijaai.v17i4.90. Iran J Allergy Asthma Immunol. 2018. PMID: 30537794 Free article.
221 results